South Carolina Hospitality Businesses for Sale: Inns, B&Bs & More

Discover a curated selection of South Carolina hospitality businesses for sale on DealStream. From beachfront resorts in Myrtle Beach and historic bed & breakfasts in Charleston to bustling restaurants and boutique hotels in Greenville, our platform connects you with prime investment opportunities across the Palmetto State. Browse detailed listings, compare asking prices, and secure the perfect hospitality venture to capitalize on South Carolina’s booming tourism market. Start your search today and take the first step toward owning a premier hotel, inn or restaurant in South Carolina.

All Matching Deals

NC Adult Strip Topless BUS+RE
South Carolina

Topless with Alcohol Pics and Financials upon signed NDA Has Private Couch and VIP Rooms 5500 sf Newly Renovated: New Chairs, Tables, HVAC, FF&E Limited Competition MSA>500,000 Real Estate from new MAI Appraisal: $1.2M Business Valued: $750K >70 Parking Spaces

$1,900,000
Details
Very Profitable SC Adult Urban Club Bus+RE
South Carolina

5000 SF Adult Urban Club Full Kitchen Full Liquor High Traffic Corner: I-20 and Broad River Road Only Urban Adult Club in Columbia, Only 1 other Adult Club in the Columbia area This building was a restaurant before. INC/EXP upon signed and verified NDA Owner will consider Owner Financing...

$1,500,000
Details
Profitable Oklahoma Topless Adult Club With RE
South Carolina

PROFITABLE TURNKEY TOPLESS OKLAHOMA CLUB WITH ALCOHOL BUSINESS AND REAL ESTATE (3 Acres) MIAMI, OKLAHOMA Imagine owning Miami, Oklahoma's premier adult entertainment venue - a turnkey operation that's been thriving for 19 years. You'll step into a profitable business with an established customer...

$800,000
Details
3 Yr Authentic Italian & Pizza $800K Sales
Greenville County, SC

3 Yr Authentic Italian & Pizza $800K Sales & Strong Profit. Are you ready to sink your teeth into a delicious opportunity? Look no further than this well-established Italian Restaurant located in Upstate South Carolina. With over 30 years of excellence in the industry and more than 3 years at the...

$450,000
Details
Sports Bar & Restaurant for Sale in South Carolina
Horry County, SC

LISTING ID # 36364 Location. Location. Location. Fantastic opportunity to acquire this award-winning restaurant/sports bar that is located in the very heart of Horry County, South Carolina. Nearby main thoroughfare adjacent to hotels and amusement parks. Wide variety menu and over 20 craft beers...

$749,000
Cash Flow: $350,000
Details
Popular Family Diner for Sale – Prime Real Estate
York County, SC

Step into ownership of a well-known, family-friendly diner. This popular establishment has earned a strong reputation for hearty breakfasts, classic comfort food, and generous portions served with Southern hospitality. With a loyal customer base, prime setup, and consistent foot traffic, this business...

$1,975,000
Details
Price Drop /  Established Pizza Place
York, SC

Popular Turn-Key Pizzeria in a very desirable Rock Hill location. A local neighborhood favorite and loved by schools, churches, and daycares. The menu includes all styles of crust pizzas, calzones, a variety of sandwiches, subs, fresh salads, and desserts as well as soft drinks. The restaurant offers...

$450,000
Details
Well Established Gourmet Dessert Vendor
Greenville County, SC

If you are looking for a proven, highly flexible business with exceptional growth potential, this is an excellent opportunity to be your own boss! Operating successfully for 11 years, the owners have perfected a seamless, low-overhead model that allows them to take 3-4 months off each year for international...

$399,000
Cash Flow: $129,539
Details
Established Seafood Restaurant for Sale – Turnkey
Richland County, SC

This well-loved seafood restaurant has been serving its community for years, offering a loyal customer base and a strong local reputation. Known for generous portions, affordable prices, and Southern-style seafood favorites, it’s a go-to spot for comfort food and casual dining. The interior features...

$300,000
Cash Flow: $128,881
Details
Neighborhood Italian Deli for Sale in SC
Horry County, SC

LISTING ID # 34329 One of a kind Italian deli. Located in a town that is currently the fastest growing town in the US. Many people moving from the North love what the deli has to offer and they expect to have numerous years of growth ahead of them. A must-see business and those looking for more info...

$525,000
Cash Flow: $200,000
Details
Tennessee Ice Cream Business For Sale
Charleston, SC

Popular event business with corporate clients Have you been dreaming of owning your an ice cream truck or shop? This is a great business opportunity to invest in a turnkey business that sells "Italian Ice & Gelato" in a growing market place. The Chattanooga region is the leading tourist market...

$80,000
Details
Japanese Restaurant with Bar for Sale
Lexington County, SC

LISTING ID # 36502 Available now is a profitable Japanese restaurant with a full bar, situated in a prime location near various commercial establishments. The building, which is 5,725 sq. ft., is also available for sale separately by the owner for an additional $1.8 million. It includes a license...

$270,000
Cash Flow: $120,000
Details
Fully Built-Out Restaurant Space in Five Points
Columbia, SC

Fully built-out restaurant space in the heart of Five Points, not currently operating. This modern build-out includes a stylish dining room, craft-cocktail bar setup, and complete kitchen—ideal for a quick relaunch. Exceptional Five Points visibility and walkability support both lunch and late-night...

$99,000
Details
Turnkey Wedding & Event Venue with Real Estate
South Carolina

Located in Upstate South Carolina, this well-established, scenic event venue offers a turnkey opportunity for a buyer seeking a reputable business with real estate. The property includes multiple structures, well-maintained grounds, and a strong mix of amenities to support a variety of wedding styles,...

$985,000
Cash Flow: $102,000
Details
Established Bar and Grill in Horry County, SC
Horry County, SC

LISTING ID # 31308 Looking for a well-known restaurant and rustic bar with killer cocktails and some of the very best seafood in the area? Look no further than our establishment! Our happy hour, lunch, and dinner menus draw in golfers, beach goers, business people, and locals alike, and our cool,...

$420,000
Cash Flow: $85,000
Details
Italian Restaurant for Sale in Greenville County
Greenville County, SC

LISTING ID # 28617 Here is the perfect, thriving restaurant in Greenville County to purchase.The restaurant has an excellent business model. They serve excellent Italian cuisine for dinner. The owner specializes in authentic Italian cuisine. They also have antipasta, seafood, veal and more. The restaurant...

$229,000
Cash Flow: $110,000
Details
Luxury Wedding & Event Venue- Profitable, Turnkey & Expanding
Myrtle Beach, SC

Exceptional opportunity to own a premier event venue located near one of the fastest-growing destination markets in the Southeast. This luxury wedding and event business is fully operational, highly profitable, and poised for massive growth. With over 40 acres of pristine land, modern infrastructure,...

$4,560,000
Cash Flow: $700,000
Details
Mobile Ice Cream Business For Sale in Charleston,
Charleston, SC

This is mobile business opportunity selling authentic Italian Ice & Gelato in 1 of top coastal cities in the country. Charleston is a great region to work and live with several beach towns. Food trucks are in high demand today. Your retail competitors must wait for customers to come to them. We take...

$120,000
Details
Unique High Traffic Dining Concept
Greenville, SC

PRICED TO SELL; One of Greenville's most unique food venues with a huge customer base that continues to grow. Seller has other business investment opportunities that needs his full attention. The business is comprised of two different concept limited service restaurants in close proximity, with a...

$160,000
Cash Flow: $107,714
Details
Bar and Restaurant for Sale in Horry County
Horry County, SC

LISTING ID # 31966 Established bar/ Restaurant in the Horry County Area for sale. This restaurant / Bar Specializes in authentic Mediterranean dishes, burgers, and hand made pizzas. The bar has an extensive craft beer selection, and a creative bar cocktails menu that will satisfy any pallet. Has...

$1,200,000
Cash Flow: $450,000
Details
North Myrtle Beach, SC

Non smoking bar in nice neighborhood Asking 299000 Rent 3200 3000 sq foot space and full kitchen Doing average 489000per year Absentee owner

On Request
Details
Turnkey SteakHouse Opportunity: $900K Revenue
Newberry County, SC

Are you ready to sink your teeth into a delicious opportunity? Look no further than this exceptional Steak Restaurant business for sale in sunny South Carolina! With a prime location in a bustling strip mall on a main road, this restaurant has been sizzling for three successful years and shows no signs...

$499,000
Cash Flow: $172,647
Details

Tips for Buying Hospitality Businesses In South Carolina

Understand Local Regulations and Licensing

South Carolina has specific regulations for hospitality businesses, especially those serving alcohol or providing accommodations. Before proceeding with a purchase, familiarize yourself with local zoning laws, business licensing requirements, food safety standards, and liquor licensing processes. Cities and counties often have different rules, so ensure that your intended business location aligns with your operational plans. Consulting with a local attorney or regulatory expert can help you avoid costly compliance issues post-acquisition.

The hospitality sector in South Carolina is heavily influenced by tourism, with hotspots like Charleston, Myrtle Beach, and Hilton Head Island attracting significant seasonal traffic. When assessing opportunities, analyze local tourism statistics, proximity to attractions, and overall market demand throughout the year. A prime location will generally command a higher purchase price but can deliver a stronger, more consistent return on investment. Don’t overlook off-the-beaten-path opportunities if they show steady local demand or unique positioning.

Review Financials and Reputation Thoroughly

Carefully examine the target business’s financial statements, tax returns, and booking records for at least the past three years. Pay special attention to occupancy rates, average revenue per guest, and seasonal variability. In the hospitality industry, online reviews and reputation can directly impact profitability—be sure to assess ratings on platforms like TripAdvisor, Google, and Yelp. Negative trends or unresolved customer complaints may point to operational issues that you'll have to address if you move forward with the purchase.