Buy Chicago Businesses for Sale – Top Illinois Opportunities
Discover top Chicago businesses for sale on DealStream, your leading destination for business opportunities in Illinois’ dynamic Second City. Whether you’re eyeing restaurants for sale in Chicago’s Loop, boutique retail shops in Lincoln Park, or service-based businesses across the city, our comprehensive listings feature detailed financials, seller financing options, and expert guidance. Find the perfect business for sale in Chicago to match your investment goals and benefit from our easy-to-navigate marketplace. Start browsing now to buy a business in Chicago and capitalize on the city’s thriving entrepreneurial landscape.
Showcased Deals
Clinical Stage Oncology for Early Cancer Detection
The Company is a clinical-stage oncology company with a platform that combines biospectral impedance and AI/ML for point-of-care cancer detection. The lead product delivers rapid, in-procedure assessment of surgical margins—identifying the presence and location of cancer within minutes. Initial commercialization...
Established Commercial Screen Printing Business
This well-established screen printing company was founded by industry professionals who recognized the growing demand for high-quality printing services. With a focus on communication, reliability, honesty, and competitive service, it has earned a strong reputation for excellence. The company has successfully...
Chicago Modern-American, Southern Inspired Cuisine
This Company provides a vibrant environment with live music, a modern American southern-inspired menu, and professional bar offerings that all continue to evolve. With a dedicated customer base and nestled in a busy part of town, this Restaurant has become a staple of the community. Business location...
All Matching Deals
Established Commercial Screen Printing Business
This well-established screen printing company was founded by industry professionals who recognized the growing demand for high-quality printing services. With a focus on communication, reliability, honesty, and competitive service, it has earned a strong reputation for excellence. The company has successfully...
Patented Athletic Vision Training Brand for Sale
An innovative sports performance company is seeking a strategic acquirer for its patented vision training technology. The flagship product is a proven, field-tested solution trusted by athletes across baseball, softball, golf, and other sports to enhance focus, depth perception, and reaction time. Operating...
Clinical Stage Oncology for Early Cancer Detection
The Company is a clinical-stage oncology company with a platform that combines biospectral impedance and AI/ML for point-of-care cancer detection. The lead product delivers rapid, in-procedure assessment of surgical margins—identifying the presence and location of cancer within minutes. Initial commercialization...
Chicago Modern-American, Southern Inspired Cuisine
This Company provides a vibrant environment with live music, a modern American southern-inspired menu, and professional bar offerings that all continue to evolve. With a dedicated customer base and nestled in a busy part of town, this Restaurant has become a staple of the community. Business location...
Chicagoland HVAC Services Company for Sale
The Company is a locally operated provider of heating, ventilation, and air conditioning services in the Chicagoland area. It specializes in the installation, maintenance, and repair of various systems, including furnaces, boilers, air conditioners, and ductless mini splits, for both residential and...
Profitable Home Lighting Ecommerce Site
Dropshipping home lighting brand with $134K revenue, $36K profit, 27% margins, and $113 AOV. Viral-ready, turnkey setup with strong growth potential Site Age 1 year Monthly Revenue USD $12,271 AVG Monthly Profit USD $3,340 /mo Profit Margin 27% Annual Revenue USD $134,981 Annual Profit USD...
Well Established Staffing & Recruiting Agency - IL
Established and profitable staffing agency in Chicago, IL. Excellent opportunity to acquire a successful agency and build on a nice book of business. Full training and ongoing support are provided for the new owner. This existing agency offers a turn-key opportunity with multiple streams of income...
Gorgeous Chicago IL Chiropractic Practice for Sale
Gorgeous Chicago chiropractic clinic with creative financing available for the down payment. Proven branding and streamlined systems support a smooth transition, while low-stress operations and EHR keep management simple. Part-time hours offer opportunities for growth + increased income. Enjoy Chicago’s...
Established Home Health Agency in Illinois
Imagine stepping into a well-established home health care business that's been serving Illinois communities since 2006. You'll find yourself owning a turnkey operation with everything already in place - three valuable licenses including Home Health, Caregiver, and Private Duty Nursing that took years...
Largest Outpatient Diagnostic Imaging Center, IL
A rare opportunity to acquire a fully licensed, multi-modality diagnostic imaging center with a long-standing reputation and proven revenue history. Located in the prestigious suburb of Oak Brook, IL, this center has been serving the Chicago healthcare market since 1985, with no adverse actions and...
$1M (Revenue) Regenerative Medicine Hub in Chicago
Broker is pleased to present Project Revival (the “Company”), a pioneering regenerative medicine hub with a proven track record in cutting-edge therapies and patient-focused care. Founded in 2018, the Company has grown into a premier destination for regenerative medicine in its market, offering a...
High Complexity Lab Licenses - Covid19
Unique Offering - COVID Asset Sale Description Immediate Sale! Great Opportunity! A High Complexity Lab Licensure is extremely time consuming and difficult to receive. This Lab License and Director allows a lab to perform a wide range of complicated medical tests: including: Covid-19 samples,...
Turnkey & Profiting: Property Damage & Restoration
This Pittsburgh property damage and restoration business is profitable and fully turn-key. The sale price includes a fully equipped van and other equipment assets and inventory. This is a high cash flow proven and recession-proof “business2business” and “business2consumer” company. The New Orleans...
Downtown Chicago CPA Practice
This well-established CPA firm offers a balanced mix of client services, generating consistent revenue and long-term client relationships. The practice provides an excellent opportunity for a buyer seeking to expand with an established book of business and strong service offerings. The owner is flexible...
Well-Established Turnkey Nail Salon
Opportunity to acquire the assets of a well-established nail salon located in Cook County. The sale includes all physical assets within the salon, offering a prime opportunity to a new owner to take over the current lease. With its prime location, this business is ready for an owner that can take...
Chicago Illinois Practice for Sale
CHICAGO, ILLINOIS - $170,000. Prime opportunity to own a well-established family chiropractic practice in the heart of Chicago. Highly visible with public transportation right at the doorstep. On-site parking available for patients. EHR w/ChiroTouch. Low rent and low overhead keep operations cost-effective....
IT Managed Services Company
We are offering for sale a full-service IT managed service company focused on small and medium-sized businesses with 10 to 100 users. The owner would like to remain with the company, managing the team and continuing to contribute as an engineer. Acquisition Highlights: *85% Recurring Revenue *Owner...
Accounting Firm with 95% Repeat Clients
This firm, founded over 20 years ago, is situated in the northwest suburbs of Chicago and specializes in tax returns. It has established a solid reputation in the community, which is reflected in its diverse client base that includes both individual and business clients. Offering a variety of...
Established Internal Medicine Practice in Chicago
For Sale: Established Internal Medicine Practice – Northwest Suburbs of Chicago Exceptional opportunity to acquire thriving internal medicine practice with deep roots in the local community and significant growth potential. This well-known and respected practice consistently generates average annual...
Commercial Snow Removal Business – 45 Years
This full-service commercial and industrial snow removal company has been a trusted name in the northwest suburbs of Cook County since 1980. Family-owned and passed from one generation to the next, the business has earned a strong reputation for reliability and quality, with many client relationships...
Franchise Home Care Agency with VA and 10 year
Long-standing in home senior care franchise for sale with over 25 current clients, over $650k in annual billing & 350+ weekly billing hours. 38+ Employees (W2s) on the caregiver roster with 27 current, active on payroll. This agency is Veterans Administration accredited as part of their Veteran’s Choice...
Fishing Bait Route, Suburban Chicago, IL to WI
Fishing Live Bait Route For Sale in the Suburban Chicago, Illinois to Wisconsin areas for $255,000! Currently grossing $250,912 and nets $82,909 per year! This business provides wholesale bait products to 335 major convenience stores and gas stations and also ships product to other parts of the country....
Gas Station For sale - Chicago
Location: South Side Chicago Price: $1.2 Million (All Cash) Property purchase option available Business Highlights: • Inside sales over $120,000 per month • Fuel sales: 20,000 gallons per month • Large store with room for expansion • Located in a high-traffic, active neighborhood • Staffed...
Southwest Chicago (Suburb), IL Practice For Sale
10-year acupuncture & oriental medicine practice collecting $226,637.00. Dr take home pay before taxes $108,302.00. 212 new patients - 4,015 total visits. Well equipped - exceptionally staffed. High visibility/high traffic/easy access. Thriving community. Small town feel with easy access to all the...
Chicago Suburb Practice for Sale
5-year acupuncture practice collecting $263,581.00. 171 new clients. 2,914 total visits. Well equipped and staffed. Plenty of room to add additional massage and/or chiropractic and physical therapy. Ideal location. High visibility – easy access. Pix available.
Tips for Buying A Business In Chicago, IL
Understand the Local Market Dynamics
Chicago’s business environment is diverse and competitive, ranging across sectors like hospitality, technology, logistics, and manufacturing. Before committing to a purchase, thoroughly research industry trends, customer demographics, and the competitive landscape specific to Chicago. Investigate how local regulations, taxes, and labor costs might affect your operations. Understanding these local nuances will give you a solid foundation for making a sound investment decision.
Conduct Comprehensive Due Diligence
An essential step in buying a business in Chicago is performing rigorous due diligence. This includes reviewing financial statements, legal contracts, employee agreements, lease terms, and any pending litigation. It’s wise to engage experienced advisors, such as accountants and attorneys familiar with Illinois business law, to ensure there are no hidden liabilities. Make sure to verify that the financial health and reputation of the company align with what has been represented by the seller.
Leverage Chicago’s Local Business Resources
Take advantage of local resources available to business buyers in Chicago. Organizations like the Small Business Development Center (SBDC) and local chapters of the Chamber of Commerce can provide valuable networking opportunities, market insights, and mentorship. These resources not only help you navigate the buying process but also enable you to become part of Chicago’s robust business community, increasing your chances of long-term success.
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