Medical Practices for Sale in Illinois – Browse Top Listings
Looking to buy a medical practice in Illinois? DealStream’s comprehensive marketplace features exclusive medical practices for sale across Chicago, Springfield, Peoria and beyond—perfect for physicians, investors and healthcare entrepreneurs. From family medicine and dental clinics to specialized care centers, our up-to-date listings make it easy to find the right acquisition at the right price. Start your search today and connect directly with verified sellers on DealStream, the leading M&A platform for healthcare practice transactions.
All Matching Deals
Turnkey Podiatry Practice – Established 20+ Years
Highly reputable podiatry and foot & ankle surgical practice located in DuPage County, Illinois, with over 20 years of consistent service to the community. This turnkey clinic offers a full range of podiatric care and maintains strong referral relationships within a major regional hospital network. The...
Independent Optical Retail & Practice - High Margins
Opportunity to acquire a well-established, independent optical retail and optometry practice with over 20 years of operating history and a loyal, insurance-driven patient base in a desirable Chicago-area suburb. The business combines premium eyewear retail, on-site optometry services, and an in-house...
Turn-Key Healthcare Clinic Available in Western IL
Established over twenty years ago, this multi-disciplinary healthcare practice delivers a unique, team-based approach to patient care. For over two decades, board-certified medical and chiropractic providers have worked together under one roof to support complete recovery and wellness, eliminating the...
Premier Fertility & Acupuncture Clinic - 20+ Year
A highly reputable acupuncture and Traditional Chinese Medicine clinic with over 20 years of established brand presence in the western Chicago suburbs. The practice specializes in fertility support, women’s health, pain management, and holistic wellness, and is known for its root-cause approach and...
Well Established Orthopedic Practice
Well established and nicely managed orthopedic practice operating in the same location for over 30 years. Located in an easily accessible Chicago suburb, this practice treats various orthopedic conditions such as sprains, strains, fractures, and chronic conditions like arthritis and bursitis. 19...
Largest Outpatient Diagnostic Imaging Center, IL
A rare opportunity to acquire a fully licensed, multi-modality diagnostic imaging center with a long-standing reputation and proven revenue history. Located in the prestigious suburb of Oak Brook, IL, this center has been serving the Chicago healthcare market since 1985, with no adverse actions and...
Physical Therapy Franchise Location in Naperville,
Seize the opportunity to own a burgeoning franchise physical therapy business situated in a high-demand suburban locale. This opportunity includes three different locations that are turnkey ready. The businesses are positioned for growth and success, boasting prime locations that attracts a steady stream...
Physical Therapy Franchise Location in Plainfield
Seize the opportunity to own a burgeoning franchise physical therapy business situated in a high-demand suburban locale. This opportunity includes three different locations that are turnkey ready. The businesses are positioned for growth and success, boasting prime locations that attracts a steady stream...
Concierge Internal Medicine Practice in Illinois
For Sale: Established Concierge Internal Medicine Practice – Vernon Hills, IL A thriving concierge practice with a strong emphasis on internal medicine is available for acquisition in Vernon Hills, Illinois. The practice operates under a membership-based model, with the concierge fee covering access...
Premier OB/GYN & Med Spa Practice – Chicago Suburb
Established in 2005, this award-winning OB/GYN and Med Spa practice offers a rare opportunity to acquire a highly regarded women’s health business with a 20-year track record in the northwest suburbs of Chicago. The practice provides comprehensive OB/GYN care across all stages of a woman’s life — including...
Established Primary & Immediate Care Clinic
Opportunity to acquire a physician-owned medical practice providing comprehensive primary and immediate care services to patients of all ages. Founded in 2018 by a board-certified family medicine doctor with over 15 years of clinical experience, the clinic has built a strong local reputation for compassionate...
Thriving Longevity Medical Center in Lake County
This is a rare opportunity to acquire a rapidly growing, state-of-the-art medical practice in Lake County, IL. Founded in 2022, the business has already achieved an impressive annual revenue of $1.6 million, reflecting strong demand, efficient operations, and a loyal patient base. The practice offers...
Established Internal Medicine Practice in Chicago
For Sale: Established Internal Medicine Practice – Northwest Suburbs of Chicago Exceptional opportunity to acquire thriving internal medicine practice with deep roots in the local community and significant growth potential. This well-known and respected practice consistently generates average annual...
Established Medical Practice, High Profit Margin
Well-established primary and preventive health care practice serving 4,000 patients within a 50-mile radius. This practice serves area communities with a personalized approach to family medicine for all stages of life, from infants to seniors. They offer comprehensive primary care services for the...
Special Medic Clinic Based in IL/IN Border
Established in mid-2022, as an offshoot of a 15-year-old PE-backed chain of medical centers, this specialized vascular clinic is focused on niche procedures and is experiencing significant growth. The clinic is owned and operated by a renowned cardiac surgeon who will stay on after transition and is...
Mental Health Clinics in Chicago Metro
The Owner is looking for a strategic partner to buy up to 100% of the company to handle the business and grow it, while the current Owner treats patients. This mental health company serves both third-party and private-pay patients and is located in the Chicago metro area. Founded in 2021, the company...
Established Neuro Feedback Clinic
Established neuro feedback clinic available for sale and transition due to a desire to retire. This clinic is very well respected in the Chicagoland area so much in fact we do not advertise or take insurance. We work with patients from all over the US and abroad , in office , in school, and remotely....
Established Dermatology Practice with Loyal Follow
Well-established dermatology practice located just outside of Chicago. The practice generates $658K in revenue and benefits from a strong reputation, established patient base, and a prime location in a desirable community. This is an excellent opportunity for a dermatologist or investor seeking a...
Behavioral Services - Autism Management Clinic
Conveniently situated in the south suburbs of Chicago, this clinic specializes in Autism Management through evidence-based Applied Behavior Analysis (ABA) therapy by providing individualized, high-quality care that empowers individuals with autism and supports their families every step of the way. The...
Optometry Practice for Sale – Chicago Area
ILLINOIS OPTOMETRY PRACTICE FOR SALE – KANE COUNTY, IL Check out this optometry to buy a private optometry practice for sale in Illinois. Located in a fast-growing area and one of the highest rated areas to live and work in Illinois and the US. This optometry business generated $970,000 in 2024 gross...
Profitable Physical Therapy Business
Well-established and highly profitable physical therapy practice with a loyal client base and strong referral network. Recognized for delivering high quality care and excellent patient outcomes. Annual revenue is $480k+ with SDE $212k. This opportunity is perfect for a licensed physical therapist, or...
Tips for Buying Medical Practices In Illinois
Understand Licensing and Regulatory Compliance
When buying a medical practice in Illinois, it is critical to thoroughly understand state licensing requirements and healthcare regulations. Medical practices are subject to oversight from the Illinois Department of Financial and Professional Regulation (IDFPR) and must comply with both state and federal healthcare laws, such as HIPAA and OSHA. Be sure to verify that the practice’s physicians and professionals possess the necessary, active licenses and certifications. Additionally, review the practice’s history concerning compliance infractions or lawsuits to avoid inheriting legal issues.
Evaluate Financial Health and Reimbursement Structures
Carefully analyze the practice’s financial records for at least the past three years. Focus on revenue streams, payer mix (private insurance, Medicare/Medicaid, self-pay), outstanding receivables, and operational expenses. Pay particular attention to how reimbursement rates may change in Illinois, especially as government and private insurers periodically revise their payment schedules. Consider seeking help from a healthcare CPA who understands practice valuations in Illinois to ensure you’re making a sound investment.
Assess Transition Plans and Patient Retention
A smooth transition is essential to retain patients and staff after acquisition. Evaluate the seller’s willingness to stay involved during a handover period, and gauge the loyalty of both employees and the patient base. In Illinois, patient relationships are vital for ongoing profitability—work with the seller to craft an effective transition plan that includes patient notifications and introductions. This will help preserve goodwill and reduce the risk of patient attrition during ownership change.
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