Discover Profitable Houston Businesses for Sale Today

Explore Houston Businesses for Sale on DealStream – the premier marketplace for buying businesses in Houston, Texas. From thriving restaurants and retail shops to tech startups and industrial ventures, our curated Houston, TX business listings showcase diverse opportunities across the Bayou City. Instantly access detailed financials, connect directly with owners, and negotiate competitive deals tailored to your goals. Start your search today to find the perfect Houston business for sale and invest in Texas’s booming economy.

All Matching Deals

Houston, TX

Growing demand in the senior care sector fuels this residential home maintenance enterprise, offering everything from routine repairs and maid service to yard management and home modifications. The company’s unique subscription-based service model prioritizes dependable, scheduled care designed to meet...

$192,500
Cash Flow: $155,124
Details
Houston, TX

Unlock seamless entry into the world of cryptocurrency with a Czech Republic-based Virtual Asset Service Provider (VASP) license. The Czech Republic boasting minimal requirements for obtaining a crypto license, no need for local substance, and no share capital requirements. Why Choose Our Services? Turnkey...

On Request
Details
Enterprise Hospitality SaaS: Remote, Scalable
Houston, TX

A modern, enterprise-grade SaaS and hardware platform serving high-volume hospitality operators across stadiums, healthcare campuses, resorts, and large institutional facilities. This technology powers thousands of daily transactions in environments where speed, accuracy, and operational efficiency...

$2,150,000
Cash Flow: $113,121
Details
Houston, TX

This business generates the majority of its revenue from commercial contracts (60–70%), many of which are recurring or multi-year agreements with nationally recognized brands such as Starbucks, Panda Express, and Popeyes, as well as the largest property management company in the U.S. These relationships...

$279,500
Cash Flow: $236,650
Details
PCR/Tox/Chem Lab
Houston, TX

This 1,200 sq. ft. laboratory with CLIA certification and COLA accreditation is set up for PCR, Toxicology, and Chemistry testing. Includes an in-network Medicare contract, providing a strong starting point for payor relationships and reimbursement. PCR equipment is included in the sale, making this...

$180,000
Details
$195K Rev – Eco-Friendly Coatings Company
Houston, TX

This company provides eco-friendly, high-performance coating solutions for residential, commercial, and industrial applications. Its proprietary product is non-toxic, solvent-free, and made from sustainable materials like castor oil and recycled gypsum, offering superior durability compared to traditional...

On Request
Details
Houston, TX

The Company provides a leading suite of software and service solutions to support healthcare providers. Products and services included are Patient Assistance Program for Prescription Drugs Software (PAP), “onshore” based Medical Billing, Credentialing, Collections and Denial Management Services, Electronic...

On Request
Cash Flow: $468,000
Details
Houston, TX

The Company is a full-service interior design firm offering materials selection assistance for new construction, turnkey remodeling services for existing homes and home furnishings including art, lighting, furniture, and custom window treatments and bedding. It provides design services, including project...

On Request
Cash Flow: $322,400
Details
Houston, TX

The Company is pioneering advanced imaging technologies that integrate laser light and ultrasound to enable high-resolution, molecular-contrast visualization of the human body. Its proprietary systems are designed for a range of clinical applications, including cancer and vascular disease diagnostics,...

On Request
Cash Flow: $86,754
Details
Houston, TX

The Company, a majority-held subsidiary of a Manufacturing Entity, provides advanced wastewater treatment through evaporation technology, offering equipment design, fabrication, use, management, and leasing across the United States. Under an exclusive contract with a specialized environmental partner,...

On Request
Cash Flow: $19,028
Details
Houston, TX

The Company is a provider of advanced data integration and virtualization solutions, offering a platform that unifies information across disparate systems in real-time without requiring physical data movement. Its proprietary technology enables enterprises to access, manage, and integrate structured...

On Request
Cash Flow: $11,490
Details
Western Wear Retail Company w/Multiple Locations
Houston, TX

The Company is a well-established Western wear retail business with a multi-decade operating history and a strong brand reputation. It operates multiple high-traffic brick-and-mortar retail locations in culturally aligned markets and serves a loyal, multi-generational customer base consisting of ranching...

On Request
Cash Flow: $3,100,000
Details
Well-Established, High-Traffic Small Animal Clinic
Houston, TX

Confidential Practice Opportunity: Houston, TX Area Well-Established, High-Traffic Small Animal Clinic with Long-Term Client Loyalty If you’ve been waiting for the right ownership opportunity in the Houston area, this might be the one. For over 20 years, this full-service veterinary hospital has...

On Request
Details
Houston, TX Area Retail Pharmacy
Houston, TX

Are you ready to step into the thriving Texas pharmacy market? We present a rare and lucrative opportunity to acquire Texas retail pharmacy with State Board of Pharmacy licenses, complete with NPI, NABP, DEA, corporation ID numbers and ALL major third party contracts! — All essential for establishing...

$175,000
Details
Established & Profitable Vet Clinic-Houston
Houston, TX

Take advantage of this rare opportunity to acquire a well-established and profitable small animal clinic in the growing Houston area. With a trusted reputation, loyal clientele, and modern upgrades, this practice is an ideal investment for veterinarians or buyers seeking a strong business with long-term...

On Request
Details
Houston, TX

Full turnkey Forex solution with 1-2 week’s timeline. - Turnkey Forex Company - Legal address on Saint-Lucia - Corporate documents - Memorandum of Association includes service of - Commercial, Financial, Lending, Borrowing, Trade, Service Activities,Contract for Difference agreements (CFD’s),...

On Request
Details
Houston, TX

Legal consulting provides FULL turnkey solution in obtaining crypto license in El Salvador Bitcoin Service Provider (BSP) License includes: - Turnkey “S.A. de C.V." (Limited Liability Corporation) formation - Legal address with lease agreement - Tailored AML/KYC/CFT Policies - Preparation of...

On Request
Details
Houston, TX

*** THIS LISTING IS CURRENTLY SALE PENDING. *** OVERVIEW Broker represents this CPA practice located in NE Houston, TX. The seller is willing to provide transitional assistance to the buyer to help ensure client retention. THE PRACTICE This is a boutique practice that is made up entirely of...

On Request
Cash Flow: $226,100
Details
High-Complexity CLIA/Medicare License Laboratory
Houston, TX

CLIA/Medicare licensed laboratory for sale in Texas. This is great for those who want a quick start to run their lab.

$150,000
Details
Houston, TX

TXPD2Q - Opportunity to Establish a Medicaid Home Care Agency in the Houston, Texas Metroplex Company Overview Broker is pleased to exclusively offer a Medicaid Certified Home Care Agency for sale in Missouri City, Texas. The company provides nonskilled care and case management services to clients...

On Request
Details
Turnkey Restaurant Space – Prime Location
Houston, TX

An excellent opportunity to acquire a second-generation restaurant space in a prime Houston trade area. Recently closed, the location is being offered as an asset sale, providing a new operator with a cost-effective path to enter one of Houston’s most competitive dining markets. The space is already...

$50,000
Cash Flow: $30,000
Details
Houston, TX

Step into ownership of a highly profitable, well-established vegan restaurant located in one of Houston’s most vibrant and upscale areas. This modern plant-based eatery has earned a stellar reputation, a loyal following, and a steady stream of repeat customers. With stylish décor, a warm atmosphere,...

$290,000
Cash Flow: $111,122
Details
Profitable Fashion Jewelry Ecommerce Site
Houston, TX

Jewelry store with custom packaging and thank you card and also more than 17000 customers. More than 10k customers that tagged Us with review and unboxing. Site Age 5 years Monthly Profit USD $472 /mo Profit Margin 52% Contact for more details.

$18,000
Details
Vibrant Mexican Cuisine Business – Solid Cash Flow
Houston, TX

This established Mexican restaurant in Houston, Texas, offers a unique opportunity for potential buyers. Originally opened in January 2010 as a franchise, the business evolved in July 2018 when the owners rebranded to introduce a broader menu featuring traditional Mexican appetizers and a fresh image....

$320,000
Cash Flow: $192,602
Details
Houston, TX

This well-established and independent transportation and logistics company has been operating successfully for over 15 years and has developed strong long-standing relationships with over 40 freight brokers and various direct customers. It currently operates intrastate only, but has the capacity to...

$78,000
Details

Tips for Buying A Business In Houston, TX

Understand the Local Market Dynamics

Houston is a diverse and rapidly growing city with unique economic drivers, including energy, healthcare, and shipping. Before considering a purchase, invest time in thoroughly researching the local market trends and demand for the business sector you are targeting. Examine Houston-specific factors, such as neighborhood demographics, local competition, and regional economic forecasts. This understanding will help you identify opportunities and avoid industries that are declining or saturated in the area.

Conduct Thorough Due Diligence

Due diligence is critical to a successful acquisition. In Houston, pay special attention to factors such as lease agreements, zoning regulations, and city permits, as these can vary greatly from other locations. Scrutinize the business’s financial statements, customer base, and supplier contracts. Engage local accountants, attorneys, and industry experts to review documents and provide insights that are specific to the Houston market landscape. Comprehensive due diligence minimizes risks and ensures there are no costly surprises after closing.

Leverage Local Networks and Resources

Networking is especially important in Houston, where many deals are influenced by local relationships and reputation. Tap into business associations, local Chambers of Commerce, and Houston entrepreneurial groups to gain insider knowledge and referrals. Utilizing local professionals—such as business brokers, commercial real estate agents, and lenders familiar with the Houston marketplace—can provide you with access to off-market opportunities and invaluable guidance throughout the buying process. Building these relationships early will also support your long-term success as a new business owner in Houston.