Browse Businesses for Sale in San Antonio, Texas | DealStream

Discover your next opportunity in the heart of Texas with our comprehensive listings of San Antonio businesses for sale. Whether you’re seeking a turnkey restaurant, a thriving retail outlet, or an established service company, DealStream’s San Antonio business marketplace connects buyers and sellers nationwide. With detailed financials, verified listings and personalized support, finding the perfect San Antonio business for sale has never been easier. Start browsing today to turn your entrepreneurial dreams into reality—explore prime San Antonio TX business opportunities now!

All Matching Deals

San Antonio, TX

This opportunity features a modern kitchen surfaces studio that specializes exclusively in cabinets and countertops, delivering a smooth experience from design consult to installation coordination in a sector where clear communication and consistent quality create a durable edge over fragmented competitors...

$455,000
Cash Flow: $406,389
Details
Small Animal Vet Practice–Prime Dallas Location
San Antonio, TX

Take advantage of this unique opportunity to acquire a highly profitable, well-established small animal clinic in a thriving Dallas community. With a strong reputation, loyal clientele, and modern facilities, this practice is ideal for veterinarians or corporations looking for a successful investment. Practice...

On Request
Details
San Antonio, TX

Take ownership of an innovative disaster restoration enterprise poised for continued success. Renowned for its wide array of services, including water and fire damage mitigation, mold remediation, contents restoration, and asbestos removal, this esteemed business stands out for its unwavering commitment...

$298,900
Cash Flow: $288,000
Details
San Antonio Veterinary Opportunity
San Antonio, TX

Ready to own a thriving veterinary practice in the heart of San Antonio? This one-doctor practice is your ticket to success, with a loyal client base, dedicated long-term staff, unbeatable visibility on a major highway, and a track record of excellence, making over $765,990 in 2022. Practice Highlights: 2,800...

On Request
Details
Award Winning Wellness & Recovery Studio
San Antonio, TX

Confidential opportunity to acquire a well-established, premium wellness and recovery studio in San Antonio, Texas. This business operates in an affluent, high-traffic retail corridor and has built an exceptional reputation for clinical-quality services, premium client experience, and strong results. The...

$325,000
Cash Flow: $105,000
Details
San Antonio, TX

Seize the chance to own a thriving, turnkey hair salon with a solid track record and prime visibility in a high-traffic location. Established in 2011, this well-established business has cultivated a loyal and diverse clientele, known for its outstanding service, talented stylists, and warm, welcoming...

$75,000
Cash Flow: $53,448
Details
San Antonio, TX

An established health and wellness franchise in San Antonio that provides clinically informed bone‑strengthening services using short, high‑intensity osteogenic loading sessions. This turnkey operation includes a well‑appointed facility, specialized equipment, an established and recurring membership...

$700,000
Cash Flow: $173,701
Details
San Antonio, TX

NEW Turnkey Startup Website Business. The website comes programmed with products and suppliers to drop ship the products for you. No programming skills or experience is required to profit from this highly lucrative industry.There is no inventory to carry and nothing to ship. You can own and operate...

$799
Details
579 – 8 Quick Service Restaurants
San Antonio, TX

A diversified portfolio of eight quick-service restaurants, providing multiple revenue streams and reducing reliance on any single location. The business is part of a nationally recognized franchise with a proven business model, and a strong, loyal customer base built over 50 years. Significant growth...

$2,500,000
Cash Flow: $595,000
Details
Turnkey Italian Dining Experience
San Antonio, TX

Upscale yet comfortable atmosphere, ideal for both casual and special dining This established Italian restaurant is a cozy, family-owned gem in the San Antonio market, offering guests an authentic taste of Italy in an inviting, upscale atmosphere. Known for its freshly prepared house-made pastas...

$179,000
Cash Flow: $50,000
Details
Growing Franchise Home Care Agency
San Antonio, TX

Established in a Growing Market - Serves Bexar & Medina Counties This is a confidential offering for a nationally recognized, in-home care franchise operating in the rapidly growing senior care industry. This established agency has been serving the West San Antonio area for over 14 years, providing...

$96,000
Cash Flow: $31,600
Details
Highly Profitable Mexican Restaurant & Bar
San Antonio, TX

Turnkey, stylish, and highly profitable Mexican restaurant available for acquisition in a high-traffic center in North San Antonio. This standout dining destination offers a modern twist on authentic Mexican cuisine, combining bold flavors with contemporary culinary innovation in a vibrant, full-service...

$572,000
Cash Flow: $341,700
Details
Highly Profitable Full Service Restaurants
San Antonio, TX

Highly Profitable - Continued Growth - Wonderful Reputation Highly profitable restaurant. The first location was established 18 years ago, building their reputation and concept, they opened a second location in 2021. The restaurant has a 4.5 Google review with 20,000 followers on social media. Their...

$400,000
Cash Flow: $173,200
Details
Fast Growing Northwest San Antonio Mexican Grill
San Antonio, TX

This Mexican Grill is a well-established, fast-growing restaurant concept celebrated for its fresh, Baja-inspired Mexican cuisine and warm, welcoming atmosphere. Strategically located in a high-traffic area of San Antonio, this restaurant has developed a loyal customer base and strong community presence. The...

$156,000
Cash Flow: $43,400
Details
Campbell's Snacks Route, San Antonio, TX
San Antonio, TX

Pepperidge Farm Cookie and Snyder’s – Lance Chips Combo route for sale in the San Antonio, Texas area for $315,000. Financing available with an estimated $58,000! down. Currently grossing $525,876 in sales and nets $83,304. Distributorship and protected territory are purchased through seller and contracted...

$315,000
Cash Flow: $83,304
Details
San Antonio, TX

The company brings over four decades of expertise in providing health monitoring solutions and comprehensive service agreements to a wide range of industries across 48 states. Trusted by leading organizations, including Fortune 500 companies, municipalities, school districts, and independent businesses,...

$4,500,000
Cash Flow: $1,049,588
Details
Established Veterinary Hospital For-Sale
San Antonio, TX

This 40+ year practice and real estate generated over $2 million in gross revenue in 2024. The sale includes the veterinary business, the real estate in which the hospital resides, and an adjacent self-storage property, providing an additional and stable profit center. Seller financing available....

$4,579,000
Cash Flow: $948,000
Details
Stretch Zone Studio San Antonio, TX Turnkey
San Antonio, TX

Franchise Opportunity – Turnkey Studio in Prime San Antonio Location Business Description Rare opportunity to acquire an established Stretch Zone franchise studio located in San Antonio, Texas at the highly visible Bandera Pointe shopping center. This location is fully operational, staffed, and...

On Request
Details
Auto-Lab Master Franchise Territory Central Texas
San Antonio, TX

Seize a unique opportunity to acquire the Master Franchise Rights for Auto-Lab Complete Car Care Centers in the Northeast Texas region. Encompassing San Antonio, Austin, Corpus Christi up to Waco. Auto-Lab, established in 1989, has grown to over 30 locations across multiple states, including Florida,...

$100,000
Details
Established San Antonio Hookah Business for sale
San Antonio, TX

Hookah Lounge is a premier hookah lounge located in San Antonio, Texas. Established in 2018, this turn-key business offers a unique "Tulum chill styled" atmosphere and has built a loyal customer base over the years. Business Highlights: - Prime location with 1,492 SF leasehold and occupancy of 49 -...

$90,000
Details
CBD & Tobacco Shop for Sale
San Antonio, TX

Profitable running business with all the certifications and legal requirements fulfilled for selling CDB, tobacco shop products, and novelty items. This business has been properly conditioned for the items with exceptional and well-lit exhibition and is well located between an active area in San...

$122,000
Cash Flow: $125K - $175K
Details
San Antonio Psychiatry Practice For Sale
San Antonio, TX

Annual Gross Revenue: $2.4M Adjusted EBITDA: $515K Texas Psychiatry Practice for sale in San Antonio, Texas. Well-established, 14-year-old Psychiatry Practice for Sale provides traditional psychiatric therapies and leading-edge therapies including TMS (transcranial magnetic stimulation) along with...

On Request
Details
San Antonio, TX

Operating outdoor lighting company is now available. Current owner is relocating and business has been run on a part time basis. Website is generating leads, good customer list, has been involved with builders and parade of homes. Extremely reasonable price so the location can get back to where...

$50,000
Details
San Antonio, TX

Small Crown and Bridge dental laboratory for sale. Great potential for growth.

$85,000
Details
San Antonio, TX

PROFITABLE LOCKSMITH BUSINESS + PROPERTY - SBA PRE-QUALIFIED SBA PRE QUALIFIED Established in April 1976, this San Antonio-based locksmith business has grown into a well-respected and deeply rooted service provider in the region. Locally owned and operated, the company offers a comprehensive...

$1,575,000
Cash Flow: $358,056
Details

Tips for Buying A Business In San Antonio, TX

Understand the Local Market

San Antonio boasts a diverse and growing economy, driven by sectors such as tourism, healthcare, cybersecurity, and military. Before making any purchase, it's essential to conduct thorough research into the local business landscape and trends specific to your target industry. Take time to analyze customer demographics, competition, and consumer preferences in the city. Connecting with local business associations or the San Antonio Chamber of Commerce can provide valuable insights and networking opportunities that help you understand the environment in which your future business will operate.

Perform Comprehensive Due Diligence

One of the most critical components of buying a business is due diligence. This involves reviewing the business’s financial statements, tax returns, legal contracts, leases, customer contracts, and any outstanding liabilities. In San Antonio, pay particular attention to zoning laws and permitting requirements, as regulations can vary by neighborhood and industry. Hiring experienced professionals—such as accountants, attorneys, and commercial real estate agents familiar with the San Antonio area—can help ensure you catch any red flags and verify the true value of the business.

Plan for Smooth Transition and Local Integration

Successful business ownership doesn’t stop after the purchase. In San Antonio, relationships and reputation matter greatly, so plan for a smooth transition with employees, vendors, and customers. Work closely with the former owner during the handover period to maintain operational continuity and leverage their knowledge of the local customer base. Attend local networking events and embrace community involvement to build your reputation and strengthen your business’s integration into the San Antonio market. This community engagement will not only help retain existing customers but also attract new ones who favor supporting local businesses.