Find Profitable Small Businesses for Sale in San Antonio, TX

Discover the best small businesses for sale in San Antonio with DealStream’s comprehensive listings. Whether you’re looking to buy a family-owned restaurant in Alamo Heights, a tech startup downtown, or a home-based service in the North Side, our San Antonio small businesses for sale span every industry and investment level. Gain instant access to detailed financials, expert deal support, and exclusive off-market opportunities. Start your journey to business ownership in one of Texas’s fastest-growing cities—browse, compare, and secure your ideal small business in San Antonio today!

All Matching Deals

579 – 8 Quick Service Restaurants
San Antonio, TX

A diversified portfolio of eight quick-service restaurants, providing multiple revenue streams and reducing reliance on any single location. The business is part of a nationally recognized franchise with a proven business model, and a strong, loyal customer base built over 50 years. Significant growth...

$2,500,000
Cash Flow: $595,000
Details
San Antonio, TX

The company brings over four decades of expertise in providing health monitoring solutions and comprehensive service agreements to a wide range of industries across 48 states. Trusted by leading organizations, including Fortune 500 companies, municipalities, school districts, and independent businesses,...

$4,500,000
Cash Flow: $1,049,588
Details
Established Veterinary Hospital For-Sale
San Antonio, TX

This 40+ year practice and real estate generated over $2 million in gross revenue in 2024. The sale includes the veterinary business, the real estate in which the hospital resides, and an adjacent self-storage property, providing an additional and stable profit center. Seller financing available....

$4,579,000
Cash Flow: $948,000
Details
San Antonio, TX

PROFITABLE LOCKSMITH BUSINESS + PROPERTY - SBA PRE-QUALIFIED SBA PRE QUALIFIED Established in April 1976, this San Antonio-based locksmith business has grown into a well-respected and deeply rooted service provider in the region. Locally owned and operated, the company offers a comprehensive...

$1,575,000
Cash Flow: $358,056
Details

Tips for Buying A Business

Do Thorough Due Diligence

Before committing to any business purchase, conduct comprehensive due diligence. Scrutinize the financials, legal documents, client contracts, and any outstanding liabilities. Review at least three years of financial statements and tax returns. Interview the seller, staff, customers, and suppliers if possible. Engaging with an accountant and legal advisor during this phase will help uncover hidden issues and give you confidence in the business’s health and potential.

Understand the Business and Industry

Gain a solid understanding of the industry and how the particular business operates within it. Analyze market trends, competitors, and the business’s position in the local market. Consider what makes this business successful—whether it's branding, customer loyalty, location, or processes. Assess whether your own skills and experience align with what the business needs to thrive, and identify areas where you can add value or drive growth.

Structure a Win-Win Deal

Negotiating the right deal terms is crucial. Look beyond just the purchase price—consider payment terms, seller financing, transition support, non-compete agreements, and warranties. Ensure the terms protect your interests but also address the seller’s needs to create a collaborative handover. A well-structured deal with clear expectations reduces risk and makes for a smoother transition, increasing your likelihood of long-term success.

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San Antonio Psychiatry Practice For Sale
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Annual Gross Revenue: $2.4M Adjusted EBITDA: $515K Texas Psychiatry Practice for sale in San Antonio, Texas. Well-established, 14-year-old Psychiatry Practice for Sale provides traditional psychiatric therapies and leading-edge therapies including TMS (transcranial magnetic stimulation) along with...

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Established San Antonio Hookah Business for sale
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Hookah Lounge is a premier hookah lounge located in San Antonio, Texas. Established in 2018, this turn-key business offers a unique "Tulum chill styled" atmosphere and has built a loyal customer base over the years. Business Highlights: - Prime location with 1,492 SF leasehold and occupancy of 49 -...

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Turnkey, stylish, and highly profitable Mexican restaurant available for acquisition in a high-traffic center in North San Antonio. This standout dining destination offers a modern twist on authentic Mexican cuisine, combining bold flavors with contemporary culinary innovation in a vibrant, full-service...

$572,000
Cash Flow: $341,700
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Growing Franchise Home Care Agency
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Established in a Growing Market - Serves Bexar & Medina Counties This is a confidential offering for a nationally recognized, in-home care franchise operating in the rapidly growing senior care industry. This established agency has been serving the West San Antonio area for over 14 years, providing...

$96,000
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Award Winning Wellness & Recovery Studio
San Antonio, TX

Confidential opportunity to acquire a well-established, premium wellness and recovery studio in San Antonio, Texas. This business operates in an affluent, high-traffic retail corridor and has built an exceptional reputation for clinical-quality services, premium client experience, and strong results. The...

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CBD & Tobacco Shop for Sale
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Profitable running business with all the certifications and legal requirements fulfilled for selling CDB, tobacco shop products, and novelty items. This business has been properly conditioned for the items with exceptional and well-lit exhibition and is well located between an active area in San...

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San Antonio, TX

Take ownership of an innovative disaster restoration enterprise poised for continued success. Renowned for its wide array of services, including water and fire damage mitigation, mold remediation, contents restoration, and asbestos removal, this esteemed business stands out for its unwavering commitment...

$298,900
Cash Flow: $288,000
Details