Des Moines, IA Businesses for Sale – Browse Opportunities Now

Find Des Moines businesses for sale on DealStream, the leading marketplace for Iowa business opportunities. Whether you’re ready to buy a turnkey café, a fast-growing service company, or a profitable retail shop in Des Moines, our curated listings cover every industry and budget. Instantly access in-depth financials, location insights, and seller disclosures to make a confident purchase decision. Browse businesses for sale in Des Moines, Iowa now and secure your next successful venture in the heart of the Hawkeye State.

All Matching Deals

Des Moines, IA

This well-established aesthetic medical practice has flourished under the current owner's leadership for two decades. Originally developed as an extension of a plastic surgery center, it has evolved into a standalone operation with a strong market presence and loyal patient base. The practice offers...

On Request
Details
Bakery with over 9 Million in Revenue
Des Moines, IA

The business employs 132 dedicated staff members across both locations. This team includes a Director of Operations who ensures consistency across all aspects of the business; Shift Leads responsible for managing teams during peak hours; Line Cooks, Cashiers, Bakery Associates, and food service...

$2,900,000
Cash Flow: $736,453
Details
Des Moines, IA

SBA Approved, National Brand, Weekly Repeat Service, Recurring Revenue If you are looking for a recession-resistant business built on repeat service that yields recurring revenue, this is it! By joining this national franchise, you’ll enjoy the freedom of being your own boss, benefit from unmatched...

$215,000
Cash Flow: $54,048
Details
Dog Kennel and Training Center for Sale
Des Moines, IA

Established for 20+ years, this business has been providing dog boarding, grooming and training services. Perfect opportunity for dog lovers. Business and real estate are for sale. Asking price business = $225,000 Asking price real estate = $575,000 Real estate is 2+ acres. Strong revenues,...

$800,000
Cash Flow: $73,000
Details

Tips for Buying A Business In Des Moines, IA

Understand the Local Market Dynamics

Before committing to a purchase, it’s crucial to familiarize yourself with the unique economic landscape of Des Moines. Research which industries are growing, such as finance, insurance, agribusiness, and technology, and identify seasonal trends that could impact revenues. Take time to analyze local competition, customer demographics, and regional regulations to ensure that the business you’re considering aligns with Des Moines' specific market opportunities and challenges.

Conduct Thorough Due Diligence

A successful acquisition depends on diligent research and careful evaluation of the business’s health. Request detailed financial statements, tax returns, and legal records going back at least three years. Examine inventory, review customer and supplier contracts, and check for liens or outstanding debts. Don’t hesitate to engage local professionals such as accountants, attorneys, or business brokers who are familiar with Iowa business practices to help you spot red flags and uncover hidden value.

Build Strong Community Relationships

Success in Des Moines, a city known for its tight-knit business network, often relies on reputation and connections. Introduce yourself to local business associations, attend Chamber of Commerce events, and connect with neighboring business owners. Building meaningful relationships within the community will not only support your transition and help retain existing customers and employees but can also open doors to fruitful partnerships, local vendors, and new business ideas tailored for the Des Moines market.

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Full Service Restaurant
West Des Moines, IA

Located in the heart of West Des Moines’ historic Valley Junction, Business is a beautiful blend of creativity, community, and culinary excellence. They’ve taken a 1916 brick building—originally a Ford dealership—and thoughtfully transformed it into one of the most unique and inviting dining spaces...

$825,000
Cash Flow: $415,394
Details
Burlington, Iowa, Practice for Sale
Burlington, IA

Well established practice collecting $88,321.00. Net cash flow [after add backs] $52,068.00. 65 new patients / 1,726 total visits. Excellent location - situated near the beautiful downtown riverfront. This is the perfect opportunity as an affordable 'entry level' turn-key practice or ideal 'satellite'...

On Request
Details
Thriving Wine & Beverage Industry Publication Biz
Humboldt, IA

Discover a unique and thriving opportunity in the wine and beverage industry with this established B2B publication business. This enterprise boasts two niche publications. These publications are offered in both print and digital formats, with physical prints released six times a year. The business...

$775,000
Cash Flow: $273,038
Details
Iowa

An esteemed medical staffing enterprise is available for purchase in the state of Iowa. This business presents a strong foundation for both profitability and growth, offering untapped potential that can be unlocked through strategic modernization and expansion efforts. By staying up-to-date with industry...

$75,000
Details
Solar Cathodic Protection Co For Sale
Texas

Reduced Asking Price due to Family Health issues. Price was $1MM but now $650,000 Cathodic Protection is Mandatory State Wide. Cathodic Protection is achieved by placing a light electrical charge on steel pipelines to prevent corrosion of pipelines transferring Oil , Gas or other materials and are...

On Request
Details