Massachusetts Medical Practices for Sale – Invest in Healthcare Businesses

Explore the most comprehensive listings of Massachusetts medical practices for sale on DealStream. Whether you’re seeking a turnkey primary care clinic in Boston, a specialty practice in Worcester, or a group healthcare business on the South Shore, our platform connects you with exclusive, fully vetted opportunities. With detailed financials, confidential buyer inquiries, and expert acquisition support, finding and purchasing the perfect medical practice for sale in Massachusetts has never been easier—start browsing today and take the first step toward owning your own healthcare business.

All Matching Deals

Massachusetts

Established in 2010 Based in Northern Massachusetts 32 Census 50% Medicare and 50% of Medicaid, Private Pay, VA & Private insurance Skilled Nursing only Passed the 36 Month Rule All of Office and Nurse Staff will Stay Total Revenue for 2024: $800K Great Opportunity for Growth! Covers:...

$450,000
Details
Premier Gastroenterology Practice – Massachusetts
Worcester, MA

New Price Adjustment: Motivated Seller! Now Only $700,000 | $350,000 Seller Financing Available Established in 1994, this leading gastroenterology practice serves central Massachusetts, offering specialized and comprehensive care for conditions including reflux, dysphagia, GI bleeding, liver and...

$700,000
Cash Flow: $944,248
Details
Norfolk County, MA

The medical practice for sale has been helping people for 26 years and has approximately 1,500 active patients. It specializes in Internal Medicine, Adolescent Medicine, and Family Medicine. The office has a great reputation, works with nearly all insurances, and comes with HUGE growth opportunities....

$399,000
Cash Flow: $332,141
Details
Massachusetts Primary Care Practice For Sale
Newburyport, MA

Busy Primary Care Practice for Sale – Newburyport Area Annual Revenue: $2M Owner Annual Compensation: $915k Asking price: $1.3M Established Massachusetts Primary Care Practice for sale located in charming Newburyport, Massachusetts, 35 miles northeast of Boston. Newburyport is an historic...

$1,300,000
Details
Multi-State Psychotherapy Practice - Relocatable
Massachusetts

Established multi-state psychotherapy practice delivering comprehensive mental health services with extra support to expats. The practice operates through both in-person and telehealth modalities, providing maximum flexibility for service delivery and ownership transition. SERVICE OFFERINGS The...

$1,300,000
Cash Flow: $404,474
Details
Optometry Practice for Sale – Massachusetts
Middlesex County, MA

MASSACHUSETTS OPTOMETRY PRACTICE FOR SALE – GREATER BOSTON, MA Finally, an affordable and successful optometry practice for sale in the Boston, Massachusetts area with the option to purchase real estate along with the practice. 2023 gross revenues at $670,000 with owner discretionary net income at...

$446,795
Cash Flow: $260,000
Details

Tips for Buying Medical Practices In Massachusetts

Understand Local Regulations and Licensing

Before considering the purchase of any medical practice in Massachusetts, thoroughly familiarize yourself with state-specific regulations, accreditation requirements, and healthcare laws. Massachusetts has its own legal framework for medical licenses, practice ownership limitations, and healthcare compliance. Carefully review Department of Public Health guidelines and confirm that the practice is operating according to all relevant laws. Involve a healthcare attorney early in the process to help you spot compliance issues or red flags that could derail your acquisition or lead to costly legal problems after the sale.

Conduct Comprehensive Due Diligence

Perform exceptionally detailed due diligence when evaluating the financial and operational health of a medical practice. Beyond standard financial statements, review patient records management, payer mix, insurance contracts, malpractice claim history, and electronic health records (EHR) system integration. It’s also wise to check patient retention rates, appointment backlogs, and staff turnover. Engage both a healthcare-savvy CPA and an experienced business broker who understands the Massachusetts market to help uncover any hidden liabilities or opportunities for growth.

Assess Reputation and Transition Planning

The goodwill and reputation of a medical practice in its local community are among its most valuable assets. Assess online reviews, referral relationships, and patient satisfaction metrics. Plan with the seller for a structured transition period to retain staff and patients post-sale, as continuity of care is critical in healthcare transactions. Make sure your transition strategy includes clear communication with both staff and patients to build trust and minimize disruption—this is especially important in tight-knit New England communities where word-of-mouth can make or break a practice’s ongoing success.