Columbus, Ohio Businesses For Sale on DealStream

Discover the best Columbus, Ohio businesses for sale on DealStream. Our extensive Ohio business listings feature turnkey operations—from thriving restaurants and retail shops to service-oriented ventures—designed to suit every entrepreneurial goal. Each Columbus business for sale includes detailed financials, industry insights, and direct seller contacts, making it easy to buy a business in Columbus with confidence. Start browsing our up-to-date marketplace today to find your perfect Columbus business opportunity and take the next step toward ownership!

All Matching Deals

Columbus, OH

Statewide Ohio Home Care Platform For Sale — $5,000,000 FIRM Confidential multi-metro Ohio home care platform with 14-county footprint. NDA required for detailed info.

On Request
Details
Columbus, OH

Ohio Medicare number for Home health. License sale only. No Patients or employees.

On Request
Details
Reduced /  Staffing Agency - Columbus, OH
Columbus, OH

Reduced Pricing! Established staffing and recruiting agency in Columbus, OH. The office provides an opportunity to acquire a turn-key business and continue to grow on an excellent book of business. Fully furnished with a trained staff and training provided for the new owner. This existing agency...

$50,000
Details
Columbus, OH

NEW Turnkey Startup Website Business. The website comes programmed with products and suppliers to drop ship the products for you. No programming skills or experience is required to profit from this highly lucrative industry.There is no inventory to carry and nothing to ship. You can own and operate...

$799
Details
Lucrative Metal Recycling & Salvage Yard
Columbus, OH

Asking Price: $8,000,000 | Location: Columbus, OH | Established: 22 Years Overview: Rare opportunity to acquire a profitable, fully licensed 6-acre metal recycling and salvage operation in Columbus, Ohio. With machinery capable of processing 22 cars per hour and a strong supply network of 12 regular...

$8,000,000
Cash Flow: $480K - $575K
Details
Columbus Walk-In Family Practice - 30+ Years
Columbus, OH

Exceptional opportunity to acquire a well-established walk-in family medicine practice serving the Columbus, Ohio metropolitan area for over 30 years. This unique practice operates on a proven "advanced access" model with no scheduled appointments, attracting 3-5 new patients daily through its convenient,...

$910,000
Details
Retail Pharmacy for Sale in Columbus, OH
Columbus, OH

An exceptional opportunity awaits in Columbus, Ohio! This established retail pharmacy, founded with care and dedication, is now seeking a motivated buyer to carry on its legacy. The current owner, ready to focus on raising a family, is looking for someone passionate about pharmacy ownership and committed...

On Request
Details
Virtual Restaurant / Ghost Kitchen W/ Highly-Rated
Columbus, OH

This listing is for a "virtual restaurant", also known as a ghost or cloud kitchen, is a food service business that serves customers exclusively by delivery and pick-up food based on phone and online ordering. The Seller has made the necessary investments in time, resources and marketing to developed...

On Request
Details
Columbus, OH

Back On The Market 12-03-2018 And Price Redued By 1 Million $10,000,000 14 Clean Properties - No Tenants - No Fuel Contract Package Deal OH. 14 Gas Stations 7 Branded 7 Unbranded No Fuel Contract Attached Cash Flow over $1 Million For Sale. Here is another Good Package of 14 gas station one owner...

$10,000,000
Cash Flow: $1,000,000
Details
Columbus, OH Practice for Sale
Columbus, OH

22 year 'successful' practice collecting $295,891.00. Net cash flow (after add backs) $204,182.00. 3,756 total visits. Open 3.5 days weekly. Columbus was named the 'fastest growing city' in the US (2024). Multibillion-dollar investments from companies like Intel & Honda (and many more)!! Great place...

$270,749
Details
Midwest Industrial Supply Company For Sale
Columbus, OH

Founded in 2007 and located in the Midwest, this company is a leading supplier of structural steel, fencing, structural steel pipe, API pipe, API valves and API fittings. They are dedicated to providing outstanding products and services to industries such as structural steel assemblies, Departments...

$4,750,000
Cash Flow: $1,035,651
Details
Mission's Tortilla Route, Columbus, OH
Columbus, OH

Mission’s Tortilla Route for sale in the Columbus, Ohio region for $86,200! Currently generating $373,527 in yearly sales and nets $68,048. Distributorship and territory are purchased through seller and contracted through Mission Foods. Mission Foods currently distributes its well-known brand of tortillas,...

$86,200
Cash Flow: $68,045
Details
Home Health Agency Medicare & Medicaid-Certified- Central Ohio
Columbus, OH

Once a multi-million-dollar agency, Business has discontinued operations following the owner’s retirement. However, with active Medicare and Medicaid certifications, established systems, and comprehensive compliance procedures still in place, the agency can be quickly reactivated and resume operations....

$250,000
Details
Dumpster Rental Company – Central OH (Fully Automated Ordering System)
Columbus, OH

This profitable and growing roll-off dumpster rental company has become a leader in the Columbus and Central Ohio market by combining exceptional customer service with a technology-driven platform that streamlines the rental process. It is the only dumpster rental provider in Central Ohio offering...

$1,000,000
Cash Flow: $166,000
Details
Medical Spa for Sale – Price Reduced -Prime Polaris Corridor, Columbus, OH
Columbus, OH

This Med Spa in the heart of the Polaris Shopping Corridor, Columbus, OH, offers an incredible opportunity to step into a thriving, high-end business. Opened just last year, the facility is brand-new, featuring state-of-the-art equipment and a modern, luxurious design. Located in a prime Class A retail...

$100,000
Details
Flooring, Kitchen & Bath Remodeler
Columbus, OH

This fully established, family owned and operated flooring and remodeling company has been a staple and respected vendor in the area for decades. The owners work full-time in the business covering finance, operations, sales and marketing. By maximizing referral and customer satisfaction to grow sales...

$3,200,000
Cash Flow: $688,289
Details
Auto Body & Repair Shop
Columbus, OH

This is a HIGHLY PROFITABLE full-service auto body and repair shop with two locations - one location does the body work accounting for 50% of sales and the other location does the repair work accounting for 40% of sales. The remaining 10% of sales are used car sales done from the repair shop location....

$2,900,000
Cash Flow: $800,000
Details
Growing Commercial Cleaning Company
Columbus, OH

100%+ growth in sales expected in 2025 over 2024 due to new contract awards! The company had $220K in SDE for 2024. Established for nearly 10 years, this ISSA Green-Compliant Business-to-Business (B2B) commercial cleaning company has a high reputation in the community and established relationships...

$800,000
Cash Flow: $220,000
Details

Tips for Buying A Business In Columbus, OH

Understand the Local Market Dynamics

Before purchasing a business in Columbus, it's essential to thoroughly research the local market. Columbus is known for its diverse economy, fueled by sectors like education, healthcare, tech, and retail. Spend time analyzing market trends, understanding population growth, and identifying neighborhoods that align with your business goals. Use resources like Columbus Chamber of Commerce and local business journals to stay informed. Knowing the unique aspects of Central Ohio’s business climate will help you identify opportunities and avoid potential pitfalls.

Conduct Comprehensive Due Diligence

A successful business acquisition depends on the quality of your due diligence. In Columbus, this means digging into the company’s financial records, customer base, supplier relationships, and licenses or permits specific to Ohio and the city. Don’t hesitate to enlist the help of local accountants or attorneys who are familiar with Ohio regulations to audit the business and alert you to red flags. Pay special attention to trends in revenue and profit, any legal or zoning issues, and existing employment contracts to minimize surprises post-purchase.

Leverage Local Networks and Resources

Building relationships in the Columbus business community can provide a huge advantage. Attend networking events, join business associations, and connect with other entrepreneurs to get firsthand advice and referrals. The city has numerous resources—such as Rev1 Ventures, Small Business Development Centers, and Ohio State University’s business programs—that offer guidance, mentorship, and growth support. Leveraging these connections early will help you access insider knowledge, gain credibility, and ensure a smoother transition once you take over the business.