Pharmacies & Drug Stores for Sale: Find Your Perfect Investment

Explore a curated selection of pharmacy businesses and drug stores for sale on DealStream. Whether you’re looking to buy an independent pharmacy, invest in a retail drug store franchise, or expand your healthcare portfolio, our easy-to-use marketplace connects you with vetted sellers nationwide. Start your search today to find the perfect pharmacy business opportunity.

All Matching Deals

Georgia Pharmacy Opportunity
Georgia

This pharmacy is fully staffed and carries clean licenses and contracts are clean and in good standing. Seller is considered to be absentee and they are ready to hand over the business to a buyer who will continue to carry on of the business and service the community as they step out of pharmacy ownership...

$795,000
Cash Flow: $427,798
Details
Texas Specialty Pharmacy Operation - two locations
Texas

Well run pharmacies with a full staff (including pharmacists, technicians, and customer service reps) who would stay on post transaction. Pharmacies are currently absentee run, making this the perfect opportunity for a buyer looking to add a pharmacy to their portfolio. Seller is looking for a buyer...

$5,850,000
Cash Flow: $2,372,429
Details
Highly Profitable Texas Pharmacy
Texas

High volume and very profitable pharmacy specializing in specific disease states. This pharmacy has been in business for over five years with continued growth. All major PBM contracts in place through PSAO. Fully staffed and easily operated by an absentee owner. Direct contracts with many pharma manufactures....

$12,950,000
Cash Flow: $4,892,969
Details
Texas Pharmacy
Texas

This pharmacy is fully staffed and easily operated by an absentee owner. Direct contracts with many pharma manufactures. Established Prior-Authorization P&P. Pharma voucher program contracts in place. Annual Sales $12,656,546.00 Gross Profit $1,239,635.60 EBITDA $559,528.00 Annual Rx Count 29081 Asking...

$1,680,000
Cash Flow: $559,528
Details
Ohio Pharmacy
Ohio

Very high-volume specialty pharmacy that has been in business for four years with continued growth. All major PBM contracts in place through PSAO. Fully staffed and easily operated by an absentee owner. Direct contracts with many pharma manufactures. Established Prior-Authorization P&P. Pharma voucher...

$5,690,000
Cash Flow: $1,726,793
Details
Illinois Specialty Pharmacy
Illinois

Profitable specialty pharmacy with continued growth. Fully staffed and easily operated by an absentee owner. Direct contracts with many pharma manufacturers. All major PBM contracts in place through PSAO. Established Prior-Authorization P&P. Pharma voucher program contracts are also in place. Annual...

$8,500,000
Cash Flow: $2,319,244
Details
Two Pharmacies in Ohio
Ohio

Two profitable independent pharmacies. Current ownership is looking to retire but will be willing to assist during transition to ensure smooth transfer of ownership. Pharmacies are fully staffed and have a loyal customers in the communities that they serve. Opportunity is preapproved with a pharmacy...

$1,525,000
Cash Flow: $537,326
Details
Minnesota Community Retail Pharmacy
Minnesota

Well run retail community pharmacy. Currently services a local patients as well as hospice centers and assisted living facilities. Fully trained and efficient staff with clean contracts and licenses. Sellers are looking to retire and are ready to hand over the business to a buyer who knows the industry...

$725,000
Cash Flow: $200,000
Details
Texas Retail Pharmacy
Texas

Great opportunity to acquire a long standing pharmacy with clean licenses and contracts. The pharmacy must be moved as the lease cannot be renewed. Licenses, contracts, FF&E and files are included. The inventory value will be taken on the day of transfer but is currently estimated to be 60k. Annual...

$150,000
Cash Flow: $46,272
Details
Texas Pharmacy in DFW area
Dallas, TX

Great opportunity to purchase clean licenses, DEA Registration with clean contracts. Long standing pharmacy within the DFW vicinity. Pharmacy is well known in the community and has a great reputation. Sellers are looking to retire. Annual Sales $1,132,533.67 Gross Profit $309,515.42 EBITDA $26,649.00 Annual...

$200,000
Cash Flow: $26,649
Details
Twin Cities Community Pharmacy
Minnesota

Twin Cities area Pharmacy is fully staffed with well-trained employees. All major PBM contracts are in place and contracted directly whenever possible. This pharmacy has a loyal customer base. Pharmacy is available for either stock or asset transaction. Licenses and contracts are all in good standing. Owner...

$675,000
Cash Flow: $301,511
Details
Well-Positioned Retail Pharmacy
Sebastian, FL

This well-positioned retail pharmacy is located in a busy strip center with excellent visibility and traffic, surrounded by medical offices, clinics, and a hospital. The site has been carefully designed for dispensing efficiency, with most of the space dedicated to pharmacy operations and a manageable...

$175,000
Details
Well-Established Retail Community Pharmacy
Palm Beach, FL

Well-Established Retail Community Pharmacy. Original owner with 11 years of steady relationships in the community. Located in high-end shopping center in central Palm Beach. Multiple Streams of revenue including Compounding, front end sales and legacy community relationships. Full compounding lab. Current...

$1,099,000
Cash Flow: $423,662
Details
Extremely Profitable Legacy Retail Pharmacy
Molino, FL

Extremely profitable legacy retail pharmacy available as the long-time owner and pharmacist prepares for retirement. This turnkey operation is fully staffed, with an experienced pharmacist and support team already in place, ensuring seamless continuity for a new owner. The business has a loyal patient...

$1,650,000
Cash Flow: $410,224
Details
Miami, FL

This well-established retail and long-term care pharmacy represents a premier opportunity in Miami-Dade County's healthcare sector. With over 18 years of continuous operation, the business has achieved recognition as a market leader in assisted living facility (ALF) and long-term care servicing throughout...

$1,400,000
Cash Flow: $389,661
Details
Community Retail Pharmacy For Sale
Clearwater, FL

Fully licensed community retail pharmacy for sale, offering all major PBM contracts, a convenient drive-through, non-sterile compounding room, and two private consulting rooms. This turnkey operation comes with a profitable homeopathic e-commerce website, established sales, and dedicated homeopathic...

$350,000
Details
Florida Pharmacy
Florida

Profitable pharmacy with further growth potential. The pharmacy is well run and fully staffed. Seller believes that all staff (including the PIC) would stay on post transaction and would be happy to work for the Buyer. Pharmacy is currently operated by an absentee owner. Clean licenses and contracts...

$3,300,000
Cash Flow: $1,043,044
Details
Florida Retail Pharmacy
Florida

This pharmacy has strong community ties and is located in the prime location with quick access to all major local highways. Clean books, licenses and contracts. The pharmacy has an overwhelmingly positive reputation among physicians and patients alike. The pharmacy is equip with top of the line software...

$14,900,000
Cash Flow: $3,975,495
Details
Nevada Retail Pharmacy
Nevada

This pharmacy in southern Nevada has had the pleasure of serving the community for over 3 years. Pharmacy fills all scripts but has a specialty in neurology. Owner is looking to retire from pharmacy ownership and is looking for a buyer with pharmacy background to take over the pharmacy and carry on...

$395,000
Cash Flow: $126,939
Details
Pennsylvania

Busy and profitable retail pharmacy in Central Pennsylvania. This pharmacy has been in business for over 20 years and has annual sales of $7.5 Million and fills over 107,000 prescriptions per year. There is approximately $350,000 in prescription inventory and $25,000 in front end inventory. LTC is...

$1,000,000
Details
Established Florida Pharmacy W/ Excellent Growth
Bradenton, FL

Community pharmacy filling 1,000+ scripts per week with 3,900+ active patients. Strong Medicare and commercial mix, 80% generic, automation in place, and experienced staff. Clean compliance record, affordable rent ($3K/mo.) in a 2,500 sq ft facility, and non-sterile compounding with statewide shipping....

$730,000
Cash Flow: $316,000
Details
Pharmacy with All Insurance Companies and Licenses
Orlando, FL

Established Retail Pharmacy. Original Owner / Operator Pharmacist (RPh). No pending audits with third parties or DEA (Full 2-5). Has all direct Insurance Contracts: CVS/Caremark, Express Scripts, Humana, Optum, Prime Therapeutics. Medicare & Florida Medicaid Provider Numbers. PSAO is AlignRx. Software...

$250,000
Details
Well-established Specialty Pharmacy For Sale
Florida

Founded in 2004, this pharmacy has built a strong reputation and a loyal customer base. With contracts with all major insurance carriers and a 340B license, this business offers a seamless transition for an experienced operator or investor looking to enter or expand within the specialty pharmacy sector. The...

$14,999,999
Cash Flow: $2,500,000
Details
Specialty Pharmacy. Turnkey Operation. Niche Focus
Miami-Dade County, FL

Closed Door Specialty Pharmacy specializing in servicing hospice patients at home and in assisted living facilities throughout Miami-Dade and Broward Counties. Prescriptions are received electronically, processed in real time through special third party insurance, and delivered daily by three contracted...

$375,000
Cash Flow: $137,279
Details
Very Profitable Retail & Compounding Pharmacy
Collier County, FL

Legacy retail and non sterile compounding pharmacy in Prime West Coast Florida location. 15 years established in a beautiful, prestigious and affluent community in sunny South West Florida. The original and current pharmacist/ owner has built an outstanding name and recognition both in the community...

$950,000
Cash Flow: $233,800
Details

Tips for Buying Pharmacies and Drug Stores

Understand Regulatory Compliance

Pharmacies and drug stores are among the most regulated types of businesses. Before buying, thoroughly research federal, state, and local regulations governing pharmacy operations, medication dispensing, controlled substance management, and insurance billing. Ensure the business has a clean compliance record, as violations can result in fines or license suspension. Working closely with specialized attorneys and consultants will help you scrutinize the store’s compliance history and uncover any past or potential legal issues.

Assess Prescription Volume and Payer Mix

The financial health of a pharmacy hinges on its prescription volume and payer mix—the proportion of revenue from cash, private insurance, Medicare, and Medicaid prescriptions. Request historical prescription data and analyze trends to ensure stable or growing sales. Evaluate the diversity of the customer base and identify any heavy reliance on a small set of physicians, facilities, or major insurance payers, as shifts could significantly impact revenue.

Review Industry Relationships and Competitive Positioning

Success in the pharmacy sector often depends on relationships with physicians, hospitals, long-term care facilities, and pharmaceutical wholesalers. Assess the business’s standing with these partners, as well as its reputation in the local community. Additionally, evaluate the competitive landscape—proximity to chain pharmacies, mail-order competition, and any local market saturation. Understanding how the pharmacy differentiates itself, for instance through personalized service, specialty compounding, or niche health products, will help determine if it has a sustainable competitive advantage.