Discover Profitable Research Triangle Businesses for Sale Today

Searching for Research Triangle businesses for sale? Discover a curated selection of established businesses and high-growth startups for sale in Raleigh, Durham and Chapel Hill on DealStream. Browse detailed listings, compare financials, and connect directly with sellers to secure your ideal investment in North Carolina’s thriving tech and research hub—start exploring today!

All Matching Deals

CPA Firm Located North of Durham
Durham, NC

This CPA firm is dedicated to providing clients with the highest level of service, ensuring clients receive personalized attention tailored to their unique needs. The team, consisting of both licensed and non-licensed professionals, is equipped to handle all accounting needs under one roof. They...

$1,500,000
Details
Christian Full Service Ad Agency for Sale
Raleigh, NC

This Christian Full-Service Advertising Agency aims to help mission-driven organizations worldwide to connect with people who share similar values and interests. It has enabled Christian-led companies to communicate a vision given by God to the world for more than 24 years! The Company’s core services...

$1,850,000
Cash Flow: $590,000
Details
Raleigh, NC

Established over 23 years ago, this promotional products business has experienced plenty of success while based in the Raleigh/Durham Metro Area. With a deep-rooted commitment to quality and customer-service, they have been consistently delivering top-notch promotional items that perfectly blend functionality...

$150,000
Cash Flow: $63,000
Details
Hot Biz, Cool Tech: Laser Lipo & Cryo Center
Wake County, NC

Turnkey Body Transformation & Weight Loss Studio in Growing NC Suburb Located in the heart of one of North Carolina’s fastest-growing suburban communities, this boutique body contouring and weight loss center offers a unique mix of non-invasive treatments, nutritional coaching, and personalized client...

$399,000
Cash Flow: $142,135
Details
High Margin Environmental Testing Lab-SBA
Raleigh, NC

This niche certification lab provides opacity and particulate matter testing services, along with specialized test filters, to major industrial clients across the U.S. and internationally. Serving utilities, refineries, pulp and paper mills, and environmental consulting firms, the business plays a vital...

$649,000
Cash Flow: $267,018
Details
Car Accessories Dropship Website Business
Durham, NC

NEW Turnkey Shopify Startup Website Business. The website comes programmed with products and suppliers to drop ship the products for you. No programming skills or experience is required to profit from this highly lucrative industry.There is no inventory to carry and nothing to ship. You can own and...

$799
Details
Raleigh, NC

NEW Turnkey Startup Website Business. The website comes programmed with products and suppliers to drop ship the products for you. No programming skills or experience is required to profit from this highly lucrative industry.There is no inventory to carry and nothing to ship. You can own and operate...

$799
Details
Backpack Ecommerce Website 14k Profit in 5 Months
Raleigh, NC

Backpack niche Made $14,210 Profit 5 Months. Trending Niche. USA Supplier. Fully Automated Store, Free Hosting for 1 Year. Aftersale Support. No Experience required. Steady monthly revenue of $2,842. The store is designed for ease of use — no inventory management, no packaging, no shipping hassles....

$7,500
Cash Flow: $14,860
Details
Towing Company for Sale in North Carolina
Wake County, NC

LISTING ID # 37129 Discover a reputable towing company in Wake County, North Carolina, known for fast response times, professional drivers, and attentive customer service. This turnkey operation benefits from a great location with easy access to major corridors, a steady stream of repeat and referral...

$275,000
Cash Flow: $100,000
Details
Fuquay-Varina, NC

Landscape Hardscape & Drainage Company servicing Wake County, NC servicing residential and commercial properties. The business has a project manager in place who helps run the business and oversees the five (5) laborers, while the owner works full-time handling mostly customer service/admin and visiting...

$750,000
Cash Flow: $258,397
Details
Wake County, NC

This is an excellent opportunity to acquire a unique, multi-location Spa. Located in Wake County, this spa offers a unique and rejuvenating self-care experience for its clients. The spa caters to those interested in relaxation, a more youthful appearance and improved health. The original location opened...

$299,000
Cash Flow: $127,444
Details
Raleigh, NC

This is an excellent opportunity to acquire an established franchised fitness studio in a great Raleigh location. It is not often that you can step into a turn-key fitness business with a growing client base and avoid the startup cost and effort of a buildout. The 4000 square foot facility includes...

$125,000
Details
Durham County, NC

NC 2073 General practice located in the highly desirable area of Raleigh/Durham North Carolina. This practice is located in a 3000 sq. ft office with 4 equipped operatories and the ability to add 2 more. Gross collections $620,000. This is a great opportunity to own a dynamic growing practice in one...

On Request
Details
Pet Bed / Medical Drape Company with Dual Utility
Raleigh, NC

Great Investment Opportunity! Rare Dual Utility Patent For Sale New Innovative Pet Bed / Medical Drape Design Raleigh Durham, NC Area 2 Start Up Businesses with Dual Utility Patent Sale Includes: Dual Utility Patent, Trademarks, Logos, Domains, Websites and Manufacturer Referrals. New innovative...

$975,000
Details
Seller Financing / Software Construction Company
Raleigh, NC

Seller is also offering a option to lease try before you buy. Please read the attached document below fro more details. We are a different type of company and you are not buying a traditional business that’s sold based on the P&L (Profit & Loss) data. Instead, our business’s estimated price is...

$1,500,000
Details
New York-Style Pizzeria in Excellent Location
Durham County, NC

For over two decades, this turnkey, iconic pizzeria has earned its legendary reputation as one of the most authentic New York-style pizzerias in the Triangle. Under current management since 2003, it quickly became a pillar of the community — a go-to destination for locals, students, and families seeking...

$2,370,000
Cash Flow: $442,254
Details
Raleigh, NC

The world’s Ultra-Premium Coffee Brand with nearly 200 years of Legacy & Global Intellectual Property Portfolio This is an extraordinary opportunity to acquire one of the world’s most exclusive and historic coffee brands, with nearly two centuries of legacy and international recognition. This offering...

$15,000,000
Details
Triangle-Area Apartment Repair & Maintenance Biz
Wake County, NC

Established Triangle-Area Leader in Building Repair & Renovation Services Serving the rapidly growing Raleigh-Durham-Chapel Hill region for over 12 years, this highly profitable building solutions company specializes in renovation, restoration, maintenance, and emergency response services for multifamily...

$1,299,000
Cash Flow: $399,013
Details
High-Margin DME & Senior Mobility Provider
Wake County, NC

A highly reputable Durable Medical Equipment (DME) provider is available for acquisition in the expanding senior mobility market in North Carolina. The Company offers consultative sales, comprehensive rentals, and repair services for critical mobility equipment, including power chairs, lift recliners,...

$130,000
Cash Flow: $89,585
Details
Seller Financing/ Software Construction Company
Raleigh, NC

Seller is also offering a option to lease try before you buy. We are a different type of company and you are not buying a traditional business that’s sold based on the P&L (Profit & Loss) data. Instead, our business’s estimated price is based on the values of our products. We are selling our company...

$1,500,000
Details
Profitable Sod Farm Distrib. Bus. SBA Pre Approved
Wake County, NC

SBA Pre Approved Markets Served: Wake, Chatham, Durham, New Hanover, Brunswick Counties & All Of Eastern NC 2023 Numbers are on track to double 2022 Numbers Fantastic Business that has stood the test of time. No end in sight for growth in our markets. Needs new blood to continue to drive and...

$2,500,000
Cash Flow: $318,287
Details
European, Mediterranean, & Middle Eastern Market
Wake County, NC

LISTING ID # 36699 Take ownership of a profitable, well-established specialty grocery store located in a bustling area of North Carolina. This thriving business caters to the growing demand for European, Mediterranean, and Middle Eastern foods, featuring unique, hard-to-find items that attract a...

$346,000
Cash Flow: $128,528
Details
Cary, NC

LOCATION Company: Allstate City/State: Cary, NC County: Wake Zip Code: 27511 Location Available: Offices are located in a bank building with separate office suites and a state-of-the-art conference room with a kitchenette. Two workstations. Rent/Lease Terms: Monthly lease renews April 2026. Rent/Lease...

On Request
Details
Arnold & Bimbo Bread Route, Garner, NC
Raleigh, NC

Arnold & Bimbo Bread Route distributorship for sale in the Garner, North Carolina area for $170,000! Company financing with $29,000 down! Currently grossing $574,964 per year in sales and nets an estimated $88,348! Distributorship and “protected territory” are purchased through independent distributor...

$170,000
Cash Flow: $88,348
Details
Indulge in Prosperity with a Dessert Business
Wake County, NC

Sweet Opportunity: Own a Profitable Dessert Shop in a Growing Market! Indulge in Success—Turn Your Culinary Passion into a Thriving Business! This established dessert shop is a golden opportunity for visionary entrepreneurs ready to lead a beloved brand into its next delicious chapter. With a proven...

$250,000
Details

Tips for Buying A Business In Research Triangle

Understand the Local Market Dynamics

Before buying a business in the Research Triangle, it's essential to thoroughly research the area's unique economic and demographic landscape. The Research Triangle—encompassing Raleigh, Durham, and Chapel Hill—is renowned for its highly educated workforce, robust tech sector, and vibrant university communities. Investigate which industries are thriving, emerging trends, and what consumer demographics are shifting. Leverage local resources such as the Chamber of Commerce, business accelerators, and industry reports to ensure your decision aligns with growth opportunities unique to this region.

Conduct Comprehensive Due Diligence

Due diligence is critical when purchasing any business, but it's particularly important in a dynamic and competitive market like the Research Triangle. Carefully analyze the business’s financial statements, customer base, supplier relationships, and legal compliance. Don’t hesitate to enlist the help of local accountants, attorneys, and business brokers who are familiar with the area’s regulations and business norms. Verify the business’s reputation both online and within the community, as the region's tight-knit networks can significantly influence future success.

Plan for Talent and Community Engagement

One of the Research Triangle’s greatest assets is its rich talent pool stemming from world-class universities and research institutions. When acquiring a business, assess the current team and imagine how you can attract and retain top talent. Additionally, consider how your business can become an active part of the local ecosystem by participating in community initiatives or relevant industry groups. Engaging with the community not only strengthens your brand but also provides access to collaboration and partnership opportunities that are particularly abundant in this innovative region.