Find Profitable Businesses for Sale in the Southeast US
Discover the largest selection of Southeast States businesses for sale on DealStream—your premier marketplace for buying and selling companies in Alabama, Florida, Georgia, North Carolina, South Carolina, Tennessee, Virginia and beyond. From turnkey restaurants and thriving retail outlets to professional services and high-growth franchises, our up-to-date listings showcase detailed financials, earnings history and seller support. Whether you’re a first-time buyer or a seasoned investor, our streamlined platform makes it easy to find the perfect business for sale in the Southeast. Start browsing top opportunities today and take the first step toward owning a profitable Southern enterprise.
Showcased Deals
Turnkey Well Built Molecular Lab in MS
Turnkey well-built molecular laboratory in Novitas (Mississippi). This CLIA Certified 3300 sq ft laboratory is currently built out for molecular testing utilizing the Biofire Film Array Torch System, QuantStudio 5k, and the KingFisher Flex for extraction. In addition to the key pieces of instrumentation,...
Professional Counseling and Healing Center
Established Counseling & Wellness Center – 25+ Years of Impact and Growth Potential This respected counseling, education, and holistic healing center has been serving individuals, couples, families, and children for over 25 years—both in-person and virtually. Known for its innovative, client-centered...
Profitable Car Lot in West Palm Beach - For Sale
Located in beautiful West Palm Beach, Florida, this car lot business presents an exceptional opportunity for ownership. Established for 4 years and under current ownership for 3 years, the business features a spacious lot that can accommodate 55+ cars, with an included office building on the premises....
All Matching Deals
Profitable Landscape Surface Solutions Enterprise
This company specializes in synthetic grass installation and maintenance for a wide range of clients. The steady demand fueled by environmental trends and water conservation needs supports reliable revenue streams. Efficient operations and diverse service offerings make this business appealing for those...
SFL Hurricane Shutter Window and Door Company
South Florida's Leading Hurricane Shutter Window, and Door Company since 1996. Residential, Commercial, High-Rise Specialists. Custom Manufacturing is done in house. Recurring high end clients in Hallandale, Broward, Miami-Dade County. All products and installations meet and surpass building guidelines....
Automated Vacation Rental Management Business
This is a turnkey, tech-driven vacation rental management company offering a fully automated, ready-to-scale business model. Operating through proprietary software, it provides end-to-end short-term rental solutions including guest booking, dynamic pricing, cleaning coordination, and maintenance oversight....
Highly Regarded Tree Service
Established and highly regarded full-service tree, pressure cleaning, and stump grinding company offering a turnkey opportunity in Palm Beach County. The business serves a strong mix of residential and commercial clients and provides tree removal, trimming, storm cleanup, ongoing maintenance, pressure...
Growing Luxury Portable Restroom Rental
This portable restroom rental business provides upgraded restroom trailers for weddings, private events, community gatherings, and professional functions. The units deliver a clean, comfortable experience that stands above standard portable toilets, giving event hosts and planners an easy way to create...
45-YR Automotive Finance Business-Recurring Income
This well-established automotive finance company generates approximately $2,600,000 in accounts receivable and has a long, proven operating history. The finance business has been in operation since 1990, supporting a car dealership that has operated successfully since 1980, creating deep-rooted industry...
Buy a High-Retention Allstate Agency
Opportunity Knocks: Acquire a highly productive, established Allstate Agency strategically located in the booming Raleigh/Durham metropolitan area (Chatham County). This turnkey opportunity offers immediate scale, proven performance, and exceptional stability. At the heart of this success story lies...
Fully Staffed $10mm Allstate Agency
Imagine walking into your own thriving Allstate Insurance agency in Metro Atlanta – one that's already generating nearly $10 million in premium and showing no signs of slowing down. This isn't just another business opportunity; it's your chance to step into a well-oiled machine that's been carefully...
Prime Opportunity To Own A Tenured Allstate Agency
A rare opportunity to acquire a highly profitable, tenured Allstate agency in a prime North Central Florida location. This agency distinguishes itself through exceptional portfolio health, boasting super-strong retention and low loss ratios across all major product lines. As an "Elite" designated agency,...
Franchise Med Spa in Growing Area of Central FL
This state of the art med spa is a prime opportunity for anyone looking to move into the industry and likes the support of a professional franchise behind them. The business comes with all of the equipment to do regenerative medicine, skin rejuvenation, hair removal, and body contouring. This established...
Industrial Building on 2.9 Acres
Positioned on nearly three acres, this 5,418± SF light industrial building offers a rare opportunity to acquire a flexible, functional facility with expansion potential in a low-density, business-friendly setting. Zoned for light manufacturing, the property has a proven operating history—having housed...
Thriving Pilates Strength Studio
This thriving Pilates strength studio brings a bold, athletic twist to traditional Pilates, delivering sweat‑driven, precision‑focused workouts for clients who want real results without high‑impact strain. The studio blends classical core principles with contemporary interval‑style programming to create...
Newly Built PCR Lab For Sale
Fully CLIA Licensed / Credentialed and molecular diagnostics laboratory in the Non-MolDX mac, North Florida area. This turnkey facility is built for high-throughput PCR testing with a complete workflow setup, ready for immediate operation. Owners are seeking $190k for an outright acquisition of all...
PCR Lab, High-Complex CLIA with New PTAN
Fully CLIA Licensed / Credentialed and molecular diagnostics laboratory in the Non-MolDX mac, North Florida area. This turnkey facility is built for high-throughput PCR testing with a complete workflow setup, ready for immediate operation. Owners are seeking $210k for an outright acquisition of all...
Premier Marine Engineering & Mechanics Business
Price Reduced! This well-established marine mechanics and engineering company has proudly served South Florida’s boating community for over 16 years. Renowned for its precision, quality, and reliability, the business has earned a strong reputation and a loyal customer base, with steady project flow...
Speech, Occupational and Physical Therapy Practice
Established Speech Therapy, Occupational Therapy, and Physical Therapy practice located in Broward County. The payor mix consists of approximately 15% private pay, 65% Medicaid, and 20% other insurance. The practice is credentialed with Medicaid and associated managed care Medicaid programs of Broward...
Executive Search Firm- Food Sciences
This national executive search firm specializes exclusively in the placement of Food Science executives, serving clients across the food, beverage, and ingredient industries. Although the owner has officially closed active operations, the firm retains extensive client and candidate databases, as...
Italian Restaurant and Bakery Food Distributor
Italian restaurant and bakery food distributor serves South Florida’s finest establishments from West Palm Beach to Miami, representing 30 premium Italian brands. With more than 55 active and loyal customers, the business has built a strong reputation for delivering authentic, high-quality products...
Fast-Casual Jamaican & Caribbean Restaurant
Established fast-casual Jamaican & Caribbean restaurant in Broward County. Founded in 2017 and operating from the same location since inception, the business has a loyal customer base and strong brand recognition. Located in a 2,280 SF modern, upscale space within a high-traffic Publix-anchored plaza....
Premium Portable Restroom Trailer Provider
This portable restroom trailer provider delivers premium restroom units for outdoor weddings, festivals, private celebrations, corporate gatherings and construction projects where clients want a cleaner, more comfortable experience than standard porta potties. The business focuses on upscale trailers...
High Margin Event Restroom Trailer Company
This event focused restroom trailer company provides upscale mobile restroom units to weddings, parties, corporate functions and outdoor gatherings, filling a specialized need for clean and comfortable facilities at venues without permanent restrooms. The business generates revenue through short term...
High‑Margin Food Service Exhaust Care Operation
This food service exhaust care operation specializes in keeping commercial kitchens clean, compliant and safe through recurring hood, duct and related equipment cleaning services. Customers include restaurants, grocery stores, institutional cafeterias, hotels, schools and care facilities that must maintain...
Scalable Synthetic Turf Solutions Provider
This business specializes in transforming outdoor spaces with high-quality synthetic turf that addresses modern landscaping needs. The focus on eco-conscious and water-efficient landscaping drives steady demand, with a service mix balancing substantial installation projects and consistent maintenance...
Turnkey South Beach Bar W 5AM License
Prime South Beach Location with 5AM License Rare chance to acquire a well-known neighborhood bar in the heart of South Beach, Miami Beach. This is a fully built-out, operating nightlife venue with loyal local clientele and consistent tourist traffic. Features include a full liquor license (4COP-5AM...
Travel & Mobile Accessories Brand / $40M+ in sales
This is a rare opportunity to acquire a profitable, IP-rich consumer lifestyle brand operating at the lucrative intersection of the $9.9T travel industry and the high-demand mobile accessory sector. With over $40 million in lifetime revenue, numerous patents for their product designs, and high-profile...
Tips for Buying A Business In Southeast States
Conduct Thorough Local Market Research
Before committing to a purchase, it’s essential to understand the unique business climate of the Southeast States. Research economic trends, customer demographics, and regional growth industries such as tourism, agriculture, and logistics. Pay attention to both state and local regulations, as these can vary and impact profitability. Engaging with local chambers of commerce and economic development agencies can also provide insight into future growth and support for business owners in the region.
Evaluate Location and Community Fit
The Southeast is known for its tight-knit communities and regional pride, so success often depends on how well your business fits with local culture and values. Assess the business’s reputation and client base, and be prepared to build relationships with suppliers, customers, and local leaders. Consider factors such as workforce availability, competition, and seasonality, especially in areas heavily dependent on tourism or agriculture.
Hire Professional Advisors Familiar With The Area
It’s wise to assemble a team of advisors—such as accountants, attorneys, and business brokers—with direct experience in the Southeast market. Local professionals can help you navigate state-specific regulations, tax incentives, and common contractual practices. Their regional expertise can help you identify risks you might otherwise overlook, ultimately smoothing your transition to ownership and setting you up for long-term success.
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