Businesses for Sale in Chester County, PA

Discover top Chester County businesses for sale in Pennsylvania on DealStream, the leading online marketplace for small and mid-sized business acquisitions. Our up-to-date, confidential listings span retail shops in West Chester, manufacturing firms near Coatesville, professional services and more—making it easy to find and secure your next profitable investment in Chester County, PA.

All Matching Deals

Chester County, Pennsylvania Practice for Sale
Chester County, PA

Total Gross Income: year-to-date in 2025 for tax book $484,204+ Net Profit: $232,418 with Owner add backs Purchase Price: $560,000 – Financing available to qualified applicants. Various programs available. Call for details. Year Established: 1990 Income Tax: Individuals: 488, Businesses: 34 Other:...

$560,000
Cash Flow: $232,418
Details
Established Smoke Shop in Prime Location
Chester County, PA

LISTING ID # 37010 This profitable and well-established smoke shop has been serving the Chester County community for over eight years. Located in a vibrant college town, the shop benefits from heavy foot traffic, consistent walk-in business, and a loyal customer base made up of students and residents....

$699,000
Cash Flow: $230,000
Details
Prime Location Smoke Shop Near Dispensary
Chester County, PA

LISTING ID # 37011 This well-situated smoke shop is a golden opportunity for the right buyer. Located in Chester County, PA, this shop sits just two doors down from a high-traffic dispensary and steps away from a busy liquor store and a thriving shopping center. The area is a magnet for foot traffic...

$309,000
Cash Flow: $103,000
Details
Prime Location Some Shop with Growth Potential
Chester County, PA

LISTING ID # 37012 This is an excellent opportunity to own a fully operational smoke shop located in a bustling shopping center in Chester County, PA. Surrounded by popular retailers and daily foot traffic, this smoke shop benefits from a steady stream of loyal customers and excellent visibility....

$289,000
Cash Flow: $95,500
Details
Three Chain Smoke Shops in Chester, PA
Chester County, PA

LISTING ID # 37013 Step into the thriving world of retail with this rare opportunity to acquire three uniquely branded, high-performing smoke shops located in Chester, Pennsylvania. These established chain locations are more than just retail stores – they are cultural cornerstones, each one bursting...

$1,267,000
Cash Flow: $428,550
Details
Profitable & Gorgeous Hair Salon
Chester County, PA

Exceptional, profitable hair salon positioned in the heart of West Chester. This established salon is known for its loyal, discerning clientele, sophisticated atmosphere, and consistent delivery of top-tier hair and beauty services. With a seasoned team already in place, this turnkey operation is perfectly...

$250,000
Cash Flow: $148,646
Details
Chester County, PA

#PA 2121 Acquire a thriving dental practice opportunity in Chester County, PA—perfect for a buyer seeking growth and stability. This thriving 6-operatory, 3,200 sq ft practice offers a well-equipped space available for lease or purchase alongside the practice. Supported by a full, experienced staff...

On Request
Details
Well-Established HVAC Company
Chester County, PA

Successful, well-established HVAC company that has serviced residential as well as commercial clients in its market for 25+ years with over 1,500 in their client database. The Company provides a full suite of heating and air conditioning services, including diagnostics, repair, replacement, ongoing...

$1,295,000
Cash Flow: $421,581
Details
Profitable Pizzeria-Chester County - Semi Absentee
Chester County, PA

Amazing opportunity to own a successful, well-established pizza restaurant in a booming area that is run semi-absentee! Owner works approximately ten hours in the business mainly handling admin work. It has a great staff that works as a team with low employee turnover. The restaurant is known for its...

$130,000
Cash Flow: $54,282
Details
Extermination Biz Net $191K-Seller Financing 80%
Exton, PA

Specialized Bed Bug Extermination Business – 80% Owner Financing Available Offered at $450,000 with generous owner financing (only 20% down) this bed bug-specific pest control company specializes in whole-house heat treatments, an effective, in-demand service with high margins and minimal competition....

$450,000
Cash Flow: $191,953
Details
Home Care Agency for Sale in PA
Chester County, PA

LISTING ID # 35152 Home based, public pay home care agency with all credentials and MCO contracts, now available. This business includes membership with American Veterans Care Connection, enabling Veterans and their surviving spouses to receive home-care and a variety of other supports and services....

$1,500,000
Cash Flow: $350,000
Details
24/7 Fitness Center-Owner Financing with 20% Down
Chester County, PA

Owner financing with only 20% down for the business! The real estate must be purchased with the business for $950,000 and the owner is also holding a note for 20 years at 6% interest with 20% down. Rare Opportunity: Profitable, 33-Year-Established 24-Hour Gym & Training Studio This is a unique...

$50,000
Cash Flow: $139,316
Details
A Beautiful 2,100 sq. ft. Pre-School Daycare
Chester County, PA

A Beautiful 2,100 sq. ft. Pre-School Daycare: Owner is retiring Expansion Potential: Opportunity to relocate the elementary program to a separate facility, unlocking capacity growth in the current preschool setup. Minimal outbound advertising and room to grow with full day curriculums. Currently...

$89,000
Cash Flow: $39,472
Details
An Indoor Playground for Kids and Parents: Chester
Chester County, PA

Rare opportunity to acquire a well-established childcare play center with a strong reputation for providing a safe, nurturing environment where children learn, play, and grow. This is a fantastic chance to step into a rewarding business with immediate revenue potential. An innovative space for parents...

$123,000
Cash Flow: $36,951
Details
Chiropractic Practice for Sale in Wilmington DE-PA
Kennett Square, PA

High-profit, thriving, and growing chiropractic practice for sale in the suburbs close to both Philadelphia and Wilmington, DE — located in Kennett Square, Pennsylvania! This business offers you a “best of both worlds” location where you are conveniently located with all the advantages of a small,...

On Request
Details
Strong and Special Cafe and Catering
Chester County, PA

LISTING ID # 34237 Long established, strong, Breakfast /Lunch & Catering business is now available for sale. This niche caterer is a very special little place. Serious and qualified buyers must see this beautiful business. A new owner might want to open earlier for breakfast and/or later for dinner...

$375,000
Cash Flow: $162,000
Details
West Chester, PA

Listing #8309 – West Chester, Pennsylvania – General dental practice available if the Philadelphia area suburb of West Chester. This office is in a high traffic location with ample opportunity for growth as it boasts a high patient to dentist ratio and high income per person in the surrounding area....

On Request
Details
Restaurant Liquor License for Sale in PA
Chester County, PA

LISTING ID # 32786 This listing is for an "R" Liquor License for Sale in the state of Pennsylvania. This listing pairs with listing 30356. To learn more, please contact the broker.

$500,000
Details
Landmark Deli and Restaurant with Liquor License
Chester County, PA

This well-known establishment is in a highly populated upscale neighborhood and has been a generational must go-to for decades. Known for its fun and friendly atmosphere, the operation is turn-key and fully staffed with loyal, long term and well-liked employees. The menu offers many delectable options...

$1,100,000
Cash Flow: $200,000
Details
Exton, PA

Angels on Guard Homecare - Non medical licensed homecare agency.

On Request
Details

Tips for Buying A Business In Chester County, PA

Understand the Local Market Dynamics

Before purchasing a business in Chester County, PA, it’s vital to thoroughly research the local economic landscape. This area boasts a diverse mix of industries, including healthcare, technology, manufacturing, and retail. Analyze local demographic trends, consumer spending habits, and regional growth patterns to ascertain which sectors are expanding. Also, connect with the Chester County Chamber of Business & Industry or similar local organizations to gain an insider’s perspective on both opportunities and challenges specific to the area.

Conduct Comprehensive Due Diligence

Never underestimate the importance of exhaustive due diligence when considering a business purchase. Beyond reviewing financial statements and tax returns, dig deeper into employee and customer contracts, supplier relationships, legal liabilities, and regulatory compliance. Pay attention to any zoning or licensing requirements that may apply uniquely within Chester County. Hiring local professionals—accountants, attorneys, and business brokers familiar with Chester County—will help surface any locality-specific risks or issues.

Assess Growth Potential and Community Fit

Investing in a business is not just about current profits; it’s about future growth. Evaluate the scalability of the business, its competitive position, and its reputation within the Chester County community. Consider how your skills and experience align with both the specific business and the preferences of the local market. Businesses that have strong ties to the community, such as those with loyal customer bases or involvement in local initiatives, often enjoy more sustained success in Chester County’s close-knit environment.