Discover Affordable Businesses for Sale in Irvine, California

Discover Irvine businesses for sale on DealStream—your premier destination for buying and selling established companies in Irvine, CA. Browse a diverse range of opportunities, from retail and tech ventures to hospitality and professional services, and connect directly with motivated sellers. Start your next entrepreneurial journey in Irvine’s thriving market today!

All Matching Deals

California High Complexity CLIA, CAP, Medicare, Me
Irvine, CA

Fully licensed high-complexity CLIA-certified clinical laboratory with CAP accreditation, Medicare, and Medi-Cal provider status. This turnkey operation offers a rare opportunity for immediate activation or relocation to the buyer’s preferred site. Price: $525,000. Established: 2025 Certifications:...

$525,000
Details
Specialized Medical Services, $160K Net, 10h/Week
Irvine, CA

Established: 1999 Annual Gross Revenue: ~$750,000 Annual Net Income: ~$160,000 Owner Time Commitment: Approximately 10 hours per week This is a highly specialized medical services company with long-standing contracts and a strong reputation across Southern California. The business provides patient...

$500,000
Cash Flow: $160,000
Details
Lab with Big Customer List, PCR, Genetic, Equipped
Irvine, CA

High complexity CLIA with certificate of Compliance, in good standing, with Medical Director, Equipment, and big customers database. Medicare is active, however offered for transfer only. Lab is not serving accounts currently, due move out of state (as a pure software company) – however very active...

$650,000
Details
Profitable Health & Skin care Brand
Irvine, CA

Established Health & Beauty Skincare Brand available for acquisition. Operating for over 4 years, this brand has a strong foundation and is positioned for significant growth. Highlights: Actively operating with distributor relationships in place. Generating consistent income with repeat orders. Proprietary...

$100,000
Details
Secured Document Management System w/Drag & Drop
Irvine, CA

Secured Document Management System w Drag & Drop Secured Document Management System (DMS) with Drag and Drop asset sales This well-established and well-connected company is a software development and provider of “Software As A Service” with highly sustainable software products in a Customer Relationship...

$195,000
Details
Cloud Erp Software With Source Code And Manual
Irvine, CA

Cloud Erp Software With Source Code And Manuals Business For Sale My ERP is a Secured and Robust ERP System Providing Best Practices, Multi-User Business Administration and Accounting Tools over a Secured Virtual Private Network with the ability for Strong Two-Factor Authentication that provides...

$525,000
Cash Flow: $1,300,000
Details
Irvine, CA

NEW Turnkey Shopify Startup Website Business. The website comes programmed with products and suppliers to drop ship the products for you. No programming skills or experience is required to profit from this highly lucrative industry.There is no inventory to carry and nothing to ship. You can own and...

$799
Details

Tips for Buying A Business In Irvine, CA

Understand the Local Market Dynamics

Before you start searching for the right business, it’s crucial to thoroughly research Irvine’s unique market environment. The city boasts a strong economy, a well-educated workforce, and a diverse population, which can make it an ideal location for both tech startups and service-oriented enterprises. Analyze sector trends, local competition, and consumer behavior to identify industries with growth potential. Being armed with this information will help you target businesses that are poised for success and better negotiate value.

Perform Comprehensive Due Diligence

Once you’ve identified a potential business to purchase, meticulous due diligence is essential. In Irvine’s competitive business landscape, it’s important to review financial statements, contracts, licenses, and customer lists thoroughly. Also, don’t overlook zoning regulations, local ordinances, and any Irvine-specific compliance requirements. This ensures you’re aware of any liabilities, operational challenges, or hidden risks before proceeding, which will ultimately protect your investment.

Leverage Professional and Community Resources

Take advantage of the wealth of resources available to business buyers in Irvine. Collaborate with local business brokers, accountants, and legal advisors who understand the intricacies of the Irvine market. Additionally, consider joining the Greater Irvine Chamber of Commerce or local business networking groups to build relationships and gain insight from established entrepreneurs. By connecting with experienced professionals and peers, you’ll gain access to off-market deals and expert guidance, greatly improving your chances of a successful acquisition.