Middle Market Businesses for Sale in Tampa, FL

Discover Tampa, Florida’s premier middle market businesses for sale on DealStream. Our curated listings showcase established, revenue-generating companies—from hospitality and healthcare to manufacturing and professional services—ready for acquisition. With detailed financials, industry-specific filters and expert guidance, finding your ideal Tampa business opportunity has never been easier. Start browsing now to invest in Tampa’s dynamic middle market and take your entrepreneurial journey to the next level.

All Matching Deals

SBA Pre-Qualified Online Spanish Tutoring Platform
Tampa, FL

Broker presents an SBA Pre-Qualified, Enterprise-Level Online Education business built around Live Spanish Tutoring and one-on-one tutoring sessions delivered via a recurring revenue model. The company is growing nicely and only uses live tutors for their lessons, something that sets them far apart...

$6,000,000
Cash Flow: $1,351,085
Details
Hair Wellness & Personal Care eCommerce Brand
Tampa, FL

Broker presents a thriving DTC eCommerce brand with a firmly established position in the Hair Wellness and Personal Care industry. This innovative company has quickly become renowned for its premium topical hair care solutions designed to address hair thinning and loss. The unique formulation of its...

$11,900,000
Cash Flow: $2,499,401
Details
Paintings On Demand Production Company
Tampa, FL

Broker presents an acclaimed Paintings-On-Demand (POD) production company that has reimagined how Handmade Paintings are bought and sold. This hyperscaler offers handmade, made-to-order paintings that are crafted in real time (post-order) by professional artists and framed by top-tier partners—resulting...

$19,000,000
Cash Flow: $3,670,900
Details
Tech-Enabled Immigration Services Co | 360+ Client
Tampa, FL

Broker presents an AI-powered Global Immigration Support Platform, purpose-built to guide elite international talent through employment-based and extraordinary-ability visa pathways with clarity, structure, and speed. Founded in 2021, this business quickly evolved into a highly trusted resource for...

$12,000,000
Cash Flow: $3,220,702
Details
Digital Marketing Agency | Lead Generation
Tampa, FL

Broker presents a high-performing Marketing Agency with a fast-growing presence in the multi-billion-dollar U.S. Insurance Market. With over a decade of experience driving results for leading insurance providers, this agency has earned an outstanding reputation for delivering qualified leads and high-intent...

$7,500,000
Cash Flow: $1,655,835
Details
22-Year Pain Relief & Joint Health Supplements
Tampa, FL

Broker presents a powerhouse 22-year-old Natural Pain Relief and Nutritional Supplement Brand that has become a trusted leader for millions of consumers seeking lasting joint, arthritis, and inflammation relief. Built on proprietary, clinically supported enzyme formulations, this company has sold over...

$13,000,000
Cash Flow: $3,239,956
Details
SBA Pre-Qual eCom Brand / Printer Ink & Toner
Tampa, FL

Broker presents an SBA Pre-Qualified, well-established eCommerce Brand specializing in Premium Printer Consumables. For more than 18 years, this company has served retail customers across the United States with OEM and compatible ink and toner cartridges, imaging drums, and printer supplies. Their reputation...

$5,500,000
Cash Flow: $1,174,321
Details
SBA PreQual | Marketing & Lead Generation Agency
Tampa, FL

Broker presents an SBA Pre-Qualified Marketing & Lead Generation Agency for the Legal Vertical that has been in operation for over 17 Years. The agency has established a dominant position through its nationwide directory platform and subscription-based services. Founded in 2008, this business combines...

$5,500,000
Cash Flow: $1,011,542
Details
Manufacturer & Distributor | Patent Portfolio
Tampa, FL

Broker presents a long-established consumer products company that has spent 18 years building a powerful portfolio of patented innovations, licensed technologies, and retail relationships across multiple high-demand categories. Operating as both a manufacturer and omni-channel distributor, the business...

$10,000,000
Cash Flow: $2,003,795
Details
Amazon FBA eCom Brand / Travel Products
Tampa, FL

Broker presents a globally recognized Amazon FBA brand specializing in Travel-focused and lifestyle products. Launched in 2018, this business quickly scaled to become a leader in its category, achieving a #1 ranking in the food warmer category across all major Amazon marketplaces. This company specializes...

$6,000,000
Cash Flow: $1,322,601
Details
Educational Platform | Programming Vertical
Tampa, FL

Broker presents an exceptional Educational Platform (Ed-Tech) that specializes in delivering top-tier programming instruction, focused in the field of Python Programming—a high-level, general-purpose computer language known for its readability and simplicity, making it a popular choice for beginners...

$5,575,000
Cash Flow: $1,140,453
Details
Retail Security Tech Stack – Patented
Tampa, FL

Broker presents an exceptional investment opportunity for companies already serving the retail industry. Offering a patent-protected product set designed to combat the growing issue of shoplifting, this company delivers a solution that enhances security while maintaining a welcoming retail environment...

$10,000,000
Details
SaaS Marketing Automation Platform | $3.7M ARR
Tampa, FL

Broker presents a SaaS Business specializing in hyper-targeted lead generation and automated customer engagement solutions. With a proprietary blend of technology, data, and creative strategy, the company helps small to mid-sized businesses—particularly in insurance, home services, and finance—attract...

$6,000,000
Cash Flow: $804,144
Details
Hollywood Science Fiction Museum  / $7M in Assets
Tampa, FL

Broker presents a great opportunity for an ambitious investor to take advantage of an assets sale that contains scores of movie props and other memorabilia worth an estimated $7+ million. These items come from a recently defunct museum in California devoted to classic science fiction and horror movies....

$7,500,000
Details
Tampa, FL

Situated in the dynamic and fast-growing Central Florida region, this distinguished furniture retailer has solidified its reputation as a leading destination for high-quality, stylish home furnishings. With a customer base that spans beyond the state of Florida, the business offers an extensive selection...

$10,000,000
Cash Flow: $977,235
Details
Super Profitable Pet Business in Tampa
Tampa, FL

This franchised Pet Store is one of the top five in the county and has room to grow with new ownership. The current owner runs it from a different city. A local new owner should be able to increase the profitability fairly significantly.

$5,300,000
Cash Flow: $1,535,919
Details
Waterfront Restaurant with Docks and Real Estate
Tampa, FL

***Real Estate included and appraised $7m)*** A Boaters Paradise and a Pirates Dream – All in One Place! Saltwater access with incredible water views surrounding you... Ah, and let’s not forget the food and libations. If you can picture this in your head – you’re already here! So, let’s get...

$11,100,000
Cash Flow: $739,648
Details

Tips for Buying A Middle-Market Business In Tampa, FL

Understand the Local Market Dynamics

Before making any offers, it’s essential to gain a deep understanding of the Tampa business landscape. Tampa’s economy is driven by a mix of tourism, healthcare, finance, and technology, which directly influences business performance and growth opportunities. Conduct market research focused on local consumer trends, regional competitors, regulatory environment, and economic forecasts. This information will help you better evaluate target businesses and allow you to spot unique opportunities or potential red flags specific to the Tampa area.

Conduct Detailed Due Diligence

When targeting middle-market businesses, the stakes are higher given the investment size and operational complexity. Rigorous due diligence is critical—review at least three years of financial statements, scrutinize tax returns, audit customer and supplier contracts, and assess key employee retention risks. In Tampa, also look closely at real estate values and lease terms, since property costs and availability can significantly impact operating expenses. Engaging local legal and financial experts is a smart move to help reveal hidden liabilities and ensure compliance with state and municipal regulations.

Build Relationships with Local Advisors and Resources

Navigating a middle-market business acquisition in Tampa is much easier with a strong local support network. Engage reputable business brokers, attorneys, accountants, and bankers who specialize in the Tampa market and understand its distinct characteristics. Their insight and connections can identify off-market opportunities, expedite negotiations, and smooth out regulatory hurdles. Additionally, joining local business associations or the Tampa Bay Chamber of Commerce can help you quickly establish credibility and integrate into the business community, positioning you for long-term success.