Businesses for Sale in Jackson, MS – Profitable Opportunities Await

Discover a curated selection of businesses for sale in Jackson, Mississippi, on DealStream—your premier marketplace for Jackson, MS business opportunities. From established restaurants and retail shops to service-based enterprises and turnkey franchises, our listings feature vetted financials, clear performance data, and direct seller connections. Whether you’re a first-time buyer or a seasoned entrepreneur, explore Jackson business opportunities tailored to your investment goals. Start browsing Jackson, MS businesses for sale today and take the first step toward acquiring a profitable Mississippi venture!

All Matching Deals

Non-Surgical Regenerative Pain Treatment Centers
Jackson, MS

Non-surgical regenerative clinics that provides medicine treatments for chronic pain caused by arthritis, injuries, or day-to-day, repetitive activities by treating damaged joints, muscles, tendons, ligaments, cartilage and connective tissue. Innovative treatments, which include Class IV deep tissue...

$600,000
Cash Flow: $748,374
Details
Premiere Pediatric Cardiology Practice For Sale
Jackson, MS

Pediatric Cardiology Practice Posed for Growth The founding physician established this practice to provide expert care in pediatric cardiology and has led it through significant growth over the past twelve years. The practice is built on core values: prioritizing patient care, ensuring needs are...

$650,000
Cash Flow: $300,142
Details
Liquor Store & Gas Station w/ Property in Jackson
Jackson, MS

Liquor Store Net Sales are $170,000 per month! Buyer can take advantage of the upcoming Holiday season sales! Gas station Inside sales are averaging $52,000 per month! Sales are increasing rapidly! ATM commission is $400 per month! Seller has recently taken full control of the gas station....

$2,799,000
Details
Jackson, MS

This established childcare business has been providing exceptional care for over 22 years. Specializing in infants, toddlers, preschoolers, and after-school care, it has built a reputation for offering a safe, nurturing, and educational environment. With a loyal client base and a strong community presence,...

$465,000
Cash Flow: $109,083
Details
No Jobber Contract /  Gas Station in Jackson, MS
Jackson, MS

No Jobber Contract! American Owned Shutdown Gas Stations with Property in Jackson, MS! Preapproved for ExxonMobil brand! Located off a major highway exit! Near schools like Jackson State University with over 4,700 students, Mississippi College, Strayer University with over 400 students, and...

$599,000
Details

Tips for Buying A Business In Jackson, MS

Do Your Homework on the Local Market

Before making any offers, thoroughly research the Jackson, MS business landscape. Understand core economic drivers in the city—including healthcare, manufacturing, and logistics. Look for businesses that not only fit your skillset but also have strong demand in the area. Analyze local competitors, customer demographics, and potential for growth within different neighborhoods. Speak with local business owners and visit the area to get an authentic feel for both opportunities and challenges.

Evaluate Financials and Perform Due Diligence

Carefully scrutinize the financial records of any business you're considering purchasing. Request at least three years of profit and loss statements, tax returns, and cash flow reports. Pay special attention to recurring revenue streams, accurate representation of expenses, and any liabilities or hidden debts. In Jackson, where the business atmosphere can be highly relationship-driven, talk with major customers and suppliers as part of your due diligence process. A strong paper trail and transparent owner will make your transition smoother.

Plan for Ongoing Support and Local Connections

Success in Jackson, MS is often about relationships. Negotiate for a transition period where the seller remains available for questions and support. Join local business groups, such as the Jackson Chamber of Commerce, to build connections and credibility. Leverage local professionals—CPAs, attorneys, and real estate agents—who understand the nuances of business in Jackson. Building a reliable network will help you navigate challenges and identify new opportunities after your purchase.