Discover Profitable Healthcare Businesses for Sale in Missouri

Explore Missouri health care businesses for sale on DealStream, featuring medical practices, urgent care centers, therapy clinics and more in Kansas City, St. Louis, Springfield and beyond. Our up-to-date listings offer detailed business profiles, competitive pricing and flexible financing options to help you invest confidently in Missouri’s booming healthcare market. Browse now to find your perfect opportunity and connect directly with sellers for a seamless deal.

All Matching Deals

Profitable Home Care Provider – Central Missouri
St Louis, MO

This Founder Operated home care company has built an award-winning reputation for compassion and professionalism. Essential services are centered around personal and companion care, enabling older adults/veterans to age in place with independence, dignity, and grace. The retiring Founders seek to...

$750,000
Cash Flow: $235,000
Details
Warrensburg MO Chiropractic Practice for Sale
Warrensburg, MO

Warrensburg clinic with strong new-patient flow, proven branding, and streamlined systems ensures a smooth transition and consistent income. Tenants provide steady rental revenue, while EHR, digital efficiency, and spacious treatment areas support continued growth. Transferable name, 200+ five-star...

On Request
Cash Flow: $133,000
Details
Missouri

MOMC1L - $1.2 Million Revenue Medicare Certified Home Health Agency in Southern Missouri Company Overview Broker is pleased to introduce a Medicare certified home health agency for sale in Southern Missouri. The company has been in business since 1996 and was created to fill a growing need for accessible,...

On Request
Details
Kansas City MO Chiropractic Practice for Sale
Kansas City, MO

Modern chiropractic clinic in Kansas City with strong new patient flow and proven marketing systems ensuring consistent income. Benefit from AR available for immediate cash flow and passive income from tenants or other providers. The clinic features digital X-ray, EHR, high-value equipment, and spacious...

On Request
Cash Flow: $19,000
Details
Saint Louis County, MO

Highly profitable medical practice with 2000+ patient list from two locations. Very positive reputation for past 20+ years. This is a leased location of 2,000 square feet with a Total monthly rent of $11,000. Lease ends month to month. Seller is active with 9 Independent contractors. Hours of operation...

$1,200,000
Cash Flow: $387,405
Details
23 Year Old Psychologist Practice With Real Estate
Missouri

Perfect business for an existing therapist or a therapist group. All the infrastructure is in place. There are currently 5 therapists in the group, and it would be easy to add more therapists and grow profit. Most of the work is done virtually but turn-key real estate is included for an additional $200k....

$125,000
Cash Flow: $46,898
Details
Missouri

The Company is a full-service rehabilitation management company employing licensed physical, occupational, and speech therapy professionals for skilled nursing facilities, assisted living facilities, and hospitals across Missouri. The Company is known and respected for its client-centric approach, high-quality...

On Request
Cash Flow: $505,000
Details
Chiropractic Practice for Springfield, MO Area
Nixa, MO

Established, Affordable chiropractic practice for sale in a growing suburb of Springfield, MO – Heart of the Ozarks and north of Branson! This well-established and profitable practice demonstrates consistent performance with three-year average collections of $319,000, featuring a favorable 75% cash...

On Request
Details
Saint Louis County, MO

The business is an established mobility solutions provider offering a comprehensive range of mobility equipment sales, rentals, repairs, and service with exclusive territory rights to 10 counties in the St. Louis Metropolitan Area. As part of a nationally recognized franchise network, the company specializes...

$170,000
Details
St Louis, MO

62 year successful 'generational' practice collecting $333,011.00. Net cash flow (after add backs) $210,688.00. 5,260 annual visits. Exceptionally equipped & staffed. Ideal location - close to Interstate 55 & minutes from Interstate 270 / 255 & 44 for easy access. All management systems in place. Current...

On Request
Details
Cassville, Missouri Practice for Sale
Cassville, MO

18 year 'part time' practice collecting $85,839.00. Net cash flow [after add backs] $61,851.00. Practice is open 1.5 days weekly. Super low overhead!! Cassville is a thriving community tucked in the Southwest corner of Missouri. Great schools - strong business environment - strong family values community...

On Request
Details
Trenton, MO, Practice for Sale
Trenton, MO

26-year practice collecting $174,571.00. 145 new patients – 3,361 total visits. Open 4-1/2 days weekly. Equipped and well staffed. All management systems in place, including EHR compliant. Ideal location. Easy access. Low stress – low overhead practice. Ideal as entry level primary or satellite location....

On Request
Details
Kansas City, MO

Medicaid agency Billing approximately 4,000 hours per month Licensed Statewide in MO Strong compliance, EVV compliant Most cases staffed by family members

$900,000
Cash Flow: $200,000
Details
St. Louis, MO, Practice for Sale
St Louis, MO

Established chiropractic and acupuncture family cash practice collecting $49,794.00. Low-low overhead. Great location – great visibility. Easy access. Ideal (low cost entry level) into “turn-key” practice. Plenty of room for growth. Next DC/L.Ac. can double/triple numbers with little effort! Current...

On Request
Details
Cape Girardeau, MO

Well established practice collecting $128,771.67. DC take home pay $59,231.86. No advertising – low overhead – low stress – enjoyable practice!! Staffed & equipped – total “turn-key” practice. Ideal opportunity as an entry level primary or satellite location. Will sacrifice for $39,500.00.

$39,500
Details
St Louis, MO

Broker is pleased to exclusively represent the “Company” in the sale of its business. Company is an organization dedicated to alleviating the financial burden of in-home care while ensuring the well-being of its clients. The company has established itself by providing high-quality in-home health services...

$3,200,000
Cash Flow: $708,363
Details
ST. Louis, MO, Practice for sale:
Missouri

Established chiropractic and acupuncture family cash practice collecting $49,794.00. Low-low overhead. Great location – great visibility. Easy access. Ideal (low cost entry level) into “turn-key” practice. Plenty of room for growth. Next DC/L.Ac. can double/triple numbers with little effort! Current...

$50,174
Details
Southeast, MO Practice for Sale:
Missouri

29 year enjoyable, low overhead practice collecting $158,254.00. 138 new patients / 2,972 total visits. Open 3 full / 2 half days weekly. Equipped and well staffed. Services include nutrition, acupuncture, physio-therapeutics, exercise and chiropractic. Plenty of room for an LMT & other services. This...

$115,096
Details
Farmington MO Chiropractic Practice For Sale
Missouri

This 20+year old diversified practice sees 20 new patients a month, 60-80 pv/wk and is contracted to do DOT physicals. The software is Chiro Touch Cloud Software. The building and equipment are in good condition with monthly rent only $740. Farmington is known as “The City of Tradition & Progress”...

On Request
Details
Kansas City (Suburbs), MO, Practice For Sale
Kansas City, MO

Well established family practice collecting $115,856.00. Dr. take home pay before taxes $63,000.00. Charming community – rich with history. Strong family - working (chiro-friendly) environment. Exceptionally equipped and staffed. High visibility – easy access. Strong patient base and name recognition....

$84,950
Details
Science-Backed Wellness Franchise | Recurring Membership Income - ~$300K Rev
St Louis, MO

This established health and wellness franchise offers a unique, science-backed model focused on bone and muscle health, located in a highly desirable and affluent community in the St. Louis metro area. The business leverages proprietary technology and complementary therapies that deliver measurable,...

$250,000
Details
Missouri

Dental laboratory with adjoining dental clinic for sale. Laboratory specializes in removable prosthesis catering to dentists locally and nationwide. Clinic is managed by the laboratory which owns the equipment and responsible for overhead. The dentist working at the clinic owns the practice and is willing...

On Request
Details
Compassionate Senior Services and Care Business
Saint Louis County, MO

Booming industry for elderly care clients. This business is a franchise opportunity as a stand-alone business or possibly an add-on to your already existing business. The current owner would be available to stay on but wants to step out of day-to-day business operations.

$148,500
Details
St. Charles County, MO Practice For Sale
Weldon Spring, MO

10 ~ year successful Regenerative Medicine practice collecting $1,024,161.00. 180 new patients / 3,000 total visits. Regenerative services include: Stem Cell / Bio Identical Hormones / Cosmetics [& more]. Beautiful facility - plenty of room for continued growth. Beautiful community! Current DO moving...

$700,502
Details
Kansas City, MO

KANSAS CITY, MO - “WHO ELSE WANTS TO PUT $31,000+ IN THEIR POCKET EVERY MONTH?” The practice is located in the exciting city of Kansas City known for its jazz, barbeque, arts, culture and professional sports teams! Visit one of the many theaters for a broadway-style show, or attend the Kansas City...

On Request
Details

Tips for Buying Health Care Businesses In Missouri

Understand Regulatory Compliance and Licensing

When considering the purchase of a health care business in Missouri, it's crucial to familiarize yourself with the state's regulatory environment. Health care is a highly regulated industry, and Missouri has specific licensing requirements for various types of facilities, such as home health agencies, nursing homes, and ambulatory surgical centers. Ensure the business you are acquiring has all the necessary licenses up to date, and verify that there are no pending compliance issues or violations. This due diligence can save you from inheriting costly legal problems or facing business disruptions.

Conduct Thorough Financial and Operational Due Diligence

Before finalizing your purchase, meticulously review the business’s financial statements, billing practices, and payer mix. Health care businesses often deal with complex reimbursement structures involving private insurance, Medicare, and Medicaid in Missouri. Ensure the business is not overly reliant on a single payer, which can be risky if reimbursement rates change. Also, examine labor costs, patient volume trends, and contracts with suppliers and service providers to identify potential red flags or opportunities for operational improvement post-acquisition.

Assess Reputation and Community Relationships

The reputation of a health care business is often one of its most valuable assets. Investigate the business’s standing among patients, referral sources, and within the broader medical community. Check online reviews, survey satisfaction scores, and any records of complaints or lawsuits. Strong ties with local physicians and hospitals can drive referrals and long-term sustainability, so consider how you will maintain or strengthen these relationships after taking over. A positive reputation and solid community network in Missouri’s tight-knit health care environment can significantly enhance your success as a new owner.