Businesses for Sale in Saint Charles County, Missouri

Discover top Saint Charles County businesses for sale in Missouri on DealStream, the premier online marketplace for buying established companies. From thriving restaurants and retail shops in O’Fallon and St. Peters to service-oriented ventures in Wentzville and Lake St. Louis, our current listings include detailed financials, real estate options, and seller insights. Whether you’re a first-time buyer or a seasoned investor, our user-friendly platform guides you to profitable opportunities tailored to your goals. Browse our Saint Charles County business listings today to buy a local enterprise and unlock prime investment potential.

All Matching Deals

Saint Charles, MO

Own a profitable, well-known cleaning franchise backed by one of the most trusted names in the industry. Chem-Dry is a global leader in carpet and upholstery cleaning services. This franchise operates in a recession-resistant industry where cleaning services remain in constant demand. Ownership is flexible,...

$90,000
Cash Flow: $32,980
Details
Absentee Ownership Possible - Day Care
Saint Charles County, MO

Absentee Ownership Possible. Our mission is to provide high-quality child care services that promote child development and growth. We strive to create a safe, nurturing, and stimulating environment where children can learn and explore. We offer a variety of programs to meet the individual needs and...

$475,000
Cash Flow: $219,020
Details
Catering Company
Saint Charles, MO

An outstanding opportunity to acquire a thriving, full service catering company with a proven track record of success and profitability. With 16 years of success, this turnkey business is a recognized leader in the corporate catering space, serving a loyal portfolio of corporate clients for executive...

$695,000
Cash Flow: $232,556
Details
Coffee Shop
Saint Charles County, MO

Great little coffee shops that has good reviews and room for growth/expansion, seller says. Also says this coffee shop sits in a niche market area without a lot of competition. Business has walk up, drive through and delivery business. This is a leased location of 1,639 square feet with a Total monthly...

$97,500
Cash Flow: $63,074
Details
Tree Service With Real Estate Investment
Wentzville, MO

This outdoor service business specializes in doing work for several real estate investment trust (REIT) customers. Business is very good and limited by finding qualified workers. The company does no advertising. Seller willing to accept $400k down and finance the remainder. In addition to tree work,...

$829,000
Cash Flow: $336,000
Details
Absentee-owned Profitable Kick Boxing Gym
Saint Charles, MO

Absentee-owned kick boxing gym franchise for sale in St. Peters Missouri! Only kick boxing gym in the area open 24x7, 365 days a year. Gym offers trainer-led, self-guided and virtual experiences. Current owner only spends 2-3 hours a week monitoring business. Gym is fully staffed and was refurbished...

$200,000
Cash Flow: $74,263
Details
Steakhouse With Old World Charm and Real Estate
Saint Charles, MO

Steakhouse that has been in the same location for 75 years! Owners are ready to retire. Recently updated the bar area with a new floor. Large walk-in refrigerator is in place to allow you to stock up as needed. Experienced employees are in place. Great chance to purchase a restaurant for less than it...

$50,000
Cash Flow: $29,500
Details
O'Fallon, MO

This well-established heavy-duty towing and recovery business has built a strong reputation for reliability, rapid response, and professional service. Serving a wide territory, the company specializes in vehicle recovery, accident response and transport. The company sets itself apart by offering long...

$225,000
Cash Flow: $114,142
Details
Saint Charles County, MO

Well-established, growing childcare center with strong community reputation and consistent annual growth. Prime location with ample parking, expansive grounds, and a facility designed specifically for early education. Significant upside potential through student population expansion or program reconfiguration....

$145,000
Details
Saint Charles County, MO

“Profitable 20+ Year Sales & Service Business – Prime Location! Long-established sales and service business with loyal B2B and B2C customers. Excellent reputation, high-traffic location, and decades of proven success. Positioned for expansion with a retiring owner ready to transition. Turnkey opportunity...

$750,000
Cash Flow: $294,945
Details
Saint Charles County, MO

Own a well-established restaurant located in one of the most desirable areas in St. Charles County. This successful, fully staffed restaurant is beautifully maintained and well-positioned for continued growth. In addition to the business, the real estate is also available, providing a rare opportunity...

$350,000
Cash Flow: $119,129
Details
Local Hotspot Bar & Grill – Music and More
Saint Charles, MO

This is a rare opportunity to acquire a well-established, fully operational bar and grill located in a high-traffic area with loyal local clientele. The business has a strong reputation for its food, drinks, and welcoming atmosphere. Situated in a prime location with high visibility, easy access, and...

$95,000
Details
Beyond the Bacon: Breakfast Restaurant For Sale
Saint Charles, MO

This is an opportunity for a well-established and highly rated breakfast and brunch restaurant with a full-service bar. Located in a bustling area with strong visibility on a high traffic road, the restaurant has become a local favorite known for its creative breakfast menu, fresh ingredients, and welcoming...

$169,000
Details
Historic Bar and Restaurant with Real Estate
Saint Charles County, MO

This full-service American-style restaurant, bar, and catering business has been a beloved dining destination for nearly 30 years, earning the loyalty of generations of guests. Nestled in one of the fastest-growing cities in the U.S., the location is unmatched—surrounded by charm, character, and steady...

$949,000
Details
St. Charles County Restaurant - Real Estate
Saint Charles County, MO

Exciting news! A historic restaurant with prime real estate in a high foot traffic location is now available! There's not a lot of real estate available and now is your chance to own a place. Bring your own concept! Fully renovated dining areas and significant upgrades in the kitchen are must sees....

$1,700,000
Details
Catering and Special Events
Saint Charles County, MO

This is your opportunity to own a state-of-the art facility and take over a Caterer's Dream! The real estate is included in this deal. Corporate business, weddings and so much more. The seller states that they turn away more than 40% business annually because they are ready to retire and move onto something...

$1,450,000
Cash Flow: $228,971
Details
Neighborhood Bar and Grill - Long Established
Saint Charles County, MO

This is an excellent opportunity for a new owner to take over this long-standing neighborhood bar & grill. Conveniently located in a shopping plaza by a major highway and roads. This is truly turn-key with new equipment included in sale. St. Charles County has a high population of 86,000 you are guaranteed...

$99,000
Details
St. Charles County Restaurant - Very Profitable
Saint Charles County, MO

High Quality restaurant in Saint Charles County making very good money that is being mostly absentee run. This restaurant and bar enjoy great sales along with a location right of the highway with a large parking lot. This is an opportunity to make excellent money from day one with a very large high...

$390,000
Cash Flow: $181,000
Details
Self Serve and Automated Car Wash with Real Estate
Saint Charles County, MO

This self-service car wash, established in 1988, offers a lucrative opportunity for a hands-on owner or investor. Situated in a high-traffic area with excellent visibility, the car wash provides consistent revenue and has a loyal customer base. Key Features: Prime Location: Located on a busy street,...

$925,000
Details
Saint Charles County, MO

Retail Vitamin & Sports Supplement/Nutrition Store for Sale. Price Dropped Recently! Great opportunity for anyone that is passionate about health & wellness and is currently active in this lifestyle. This is a 100% turnkey operation that is fully stocked, low overhead, and located in a high traffic...

$40,000
Details
O'Fallon, MO

Perfect opportunity for a Drywall Professional looking to become an owner-operator and experience unlimited income potential, flexible hours, in a project-based environment. Customers pay for most services check or credit card the day of completion. This Semi-Absentee owner PatchMaster franchisee holds...

$99,999
Details
City of Saint Peters, MO

Established $1.5 million ECP agency in dynamic and growing St. Peters, MO, just outside of St. Louis. Agency consists of a preferred auto and homeowner customer base with excellent opportunity for growth in cross sales, as well as life/financial services. This agency sale creates a wonderful opportunity...

$249,000
Details
Augusta, MO

Investment Opportunity! A traditional distillery, R&D, and brand creation facility focused on Whiskey (a brand-new legal category of spirits), with the additional ability to distill and import any spirit in the heart of the Missouri Wine Country and the Ozark Highlands. This distillery currently has...

$100,000
Details
Busy Pizza Restaurant - Dine in and Carry Out
Saint Charles County, MO

This restaurant has been in business for several years and took over a pizza place that had been there for 17 years. The previous owners thrived in this place for a long time but moved onto retirement. The current owner has a lot going on and needs to step away from this business. The original phone...

$75,000
Details
St. Charles County, MO Practice For Sale
Weldon Spring, MO

10 ~ year successful Regenerative Medicine practice collecting $1,024,161.00. 180 new patients / 3,000 total visits. Regenerative services include: Stem Cell / Bio Identical Hormones / Cosmetics [& more]. Beautiful facility - plenty of room for continued growth. Beautiful community! Current DO moving...

$700,502
Details

Tips for Buying A Business In Saint Charles County, MO

Understand the Local Market Dynamics

Before making any purchase, it’s crucial to conduct thorough research on the local market in Saint Charles County. Investigate which industries are thriving in the area and whether there are any oversaturated markets to avoid. Consider factors like population growth, local consumer behavior, and economic forecasts unique to Saint Charles County. Engaging with local business groups or the Chamber of Commerce can help you gain valuable insights and connect you with trusted professionals.

Conduct Detailed Due Diligence

Once you find a potential business, prioritize a comprehensive due diligence process. Review all financial records, tax returns, customer contracts, and legal documents related to the business. Pay special attention to any local licenses or city and county regulations specific to Saint Charles County that might impact your ability to operate the business legally and efficiently. Hiring local accountants and legal advisors can help ensure there are no hidden liabilities that could jeopardize your investment.

Plan for a Smooth Transition

After the purchase is completed, a smooth transition is essential for retaining customers and employees. Develop a detailed transition plan that includes communication with staff, training sessions, and maintaining good relationships with existing suppliers and customers in Saint Charles County. Whenever possible, involve the previous owner in the handover process for a set period to minimize disruptions and preserve business continuity for the local community you’ll be serving.