Buy Medical Practices for Sale in the United States | DealStream

Explore Medical Practices for Sale in the United States on DealStream, the premier online marketplace for buying and selling healthcare businesses. Our comprehensive, expertly vetted listings feature physician-owned clinics, specialty offices, and multi-location facilities across every state—complete with detailed financials and direct seller contacts. Whether you’re a doctor seeking to buy a medical practice or an investor pursuing profitable healthcare opportunities, our powerful search tools and dedicated support simplify your acquisition journey. Start browsing now to find the perfect medical practice for sale and take the next step toward owning a thriving healthcare business.

All Matching Deals

Franchise Med Spa in Growing Area of Central FL
Winter Garden, FL

This state of the art med spa is a prime opportunity for anyone looking to move into the industry and likes the support of a professional franchise behind them. The business comes with all of the equipment to do regenerative medicine, skin rejuvenation, hair removal, and body contouring. This established...

$65,000
Details
Mental Health Counseling Practice $2.7M Revenue
United States

Experience extraordinary growth in the healthcare sector with a proven, scalable multi-location Midwestern mental health practice. This is a rare opportunity to acquire a thriving mental health organization that has successfully scaled to 4 strategic locations across a prime Midwest market. Combining...

$2,100,000
Cash Flow: $325,000
Details
PI Rehab & Ortho/Neuro Group – Absentee Owner
Tampa, FL

This listing is for an established personal injury–focused medical group in Boca Raton, Florida, consisting of: A rehab/therapy clinic providing chiropractic and physical medicine services to auto accident and slip-and-fall patients, and a complementary orthopedic & neurosurgery practice providing...

$1,800,000
Cash Flow: $607,468
Details
General Practice Medical Office w Active Contracts
Broward County, FL

Well-established General Practice medical office with active payer contracts in place with all major insurance carriers, including BCBS/Blue Cross Blue Shield of Florida, Cigna, Humana, UnitedHealthcare, and others. The practice is supported by an experienced team consisting of a full-time Medical...

$450,000
Cash Flow: $103,345
Details
Profitable and Growing Endocrinology Practice
Volusia County, FL

Profitable and Expanding Endocrinology Practice – North Central Florida Well-established and steadily growing endocrinology practice located in North Central Florida, with over 19 years of service to the community. The practice is currently staffed by a board-certified medical doctor who is expected...

$890,000
Cash Flow: $276,366
Details
Prescribed Pediatric Extended Care Facility
Miami, FL

Profitable Prescribed Pediatric Extended Care Facility (PPEC) with license to service 21 children located in Southwest Miami. Current census is 6 children. Payer source is 100% Medicaid. Services include 2 meals + Snacks, extended care in facility 6 days per week as well as transportation. Medical...

$675,000
Cash Flow: $236,800
Details
Solo General Practice with Insurance Contracts
Naples, FL

Established solo general practice clinic located in Naples, Florida. The physician is seeking an immediate sale and is open to all reasonable offers. The clinic is credentialed with major insurance providers including Blue Cross Blue Shield, Medicare, Medicaid and UnitedHealthcare. It operates out...

$120,000
Cash Flow: $118,996
Details
Professional Counseling and Healing Center
Broward County, FL

Established Counseling & Wellness Center – 25+ Years of Impact and Growth Potential This respected counseling, education, and holistic healing center has been serving individuals, couples, families, and children for over 25 years—both in-person and virtually. Known for its innovative, client-centered...

$250,000
Cash Flow: $104,869
Details
Lakeville, MN

Don't miss out on one of the fastest growing market segments by owning a highly desirable Game Day Men's Health franchise. The global men's health and wellness market is valued at $1.27 Trillion and is expected to grow to $2.59 Trillion by2029. Territories are mostly taken, and this available resale...

$55,000
Details
Sunnyvale, TX

Executive Summary Primary Care Clinic is a long‑established family medicine clinic located in the Dallas–Fort Worth metroplex. The practice has been serving the community for more than 42 years and has built a large and loyal patient panel of 3,367 patients (2017–2024). The clinic’s operations are...

On Request
Details
$940K Revenue –  Wellness & Therapy Clinic
Austin, TX

This clinic provides ketamine-assisted therapy alongside services like NAD+ and IV vitamin infusions, with a focus on ethical, client-centered care. Founded in 2018, it has built a strong reputation through individualized and group programs, integration support, and trusted community partnerships. With...

On Request
Details
Turnkey Aesthetics & Anti-Aging Practice
San Diego, CA

This thriving, physician-founded aesthetics and anti-aging practice operates on a unique, cash-only model that blends advanced aesthetic services with functional and preventive medicine. Since opening in 2018, the clinic has grown organically to generate over $2.2 million in annual revenue by 2022—without...

$990,000
Cash Flow: $408,260
Details
Aesthetic Dermatology Practice - Growth Potential
Boca Raton, FL

This is a rare opportunity to acquire a well-established, boutique aesthetic dermatology practice led by a highly respected physician in the heart of Palm Beach County. With over 35 years of experience, the current provider has built a loyal, long-term patient base and an outstanding reputation for...

$550,000
Cash Flow: $256,125
Details
Profitable Orthopedic & Osteopathic Practice
Boynton Beach, FL

This is a rare and trusted expansion opportunity to acquire a highly respected, profitable medical practice specializing in orthopedic and osteopathic care. The practice is anchored by a well-known physician with decades of loyal clientele and a consistent patient volume. Located in a prime, high-demand...

$1,600,000
Cash Flow: $352,010
Details
Established Behavioral Health Practice
Denver, CO

Established outpatient behavioral health provider with embedded court referral b This Colorado-based behavioral health provider offers outpatient and intensive outpatient services to a high-demand, court-referred population. Founded nearly 30 years ago, the business is built around compliance-first...

$1,518,062
Cash Flow: $191,228
Details
Profitable/High Margin Dry Eye & Glaucoma Optometry
Flower Mound, TX

Location: Flower Mound, TX Asking Price: $3.5 million (Business Only) Practice Snapshot • Established: 20 years • Specialty: Optometric dry eye and glaucoma treatment • Facility: 2,600 sq. ft., 3 exam rooms, in-house optical lab and boutique • Technology: $1.5MM+ in fully paid, state-of-the-art...

$3,500,000
Cash Flow: $500K - $1MM
Details
Established Multi-Location Psychiatric Practice
Volusia County, FL

This well-established psychiatric practice operates across three strategic locations, providing comprehensive mental health services to a loyal and growing patient base. Led by a board-certified psychiatrist, the practice offers a range of treatments and services, supported by a skilled team of professionals....

$3,700,000
Cash Flow: $1,258,351
Details
Established Ophthalmology Practice
Gulfport, MS

This well-established ophthalmology clinic has been serving the community for over four decades, offering comprehensive eye care, routine exams, glaucoma treatments, and an in-house optical shop. With a strong patient base of 25,000+, steady referral streams, and significant growth potential in cataract...

$775,000
Cash Flow: $344,447
Details
Profitable Independent MRI Imaging Center
Oakland County, MI

This MRI imaging center in Southeast Michigan has built a solid reputation for quality diagnostics, fast turnaround, and reliable service to physicians, clinics, and patients. The business operates from a clean, professional medical facility with updated equipment and experienced staff. With steady...

$999,000
Cash Flow: $282,772
Details
Established & Thriving Cardiology Practice
Curry County, NM

This well-established cardiology practice, operating for over 18 years, presents a rare acquisition opportunity in a high-demand medical market. The practice serves 4,000+ active patients, with a strong referral network. With a diverse payer mix, including commercial insurance, Medicaid, and self-pay...

$1,090,000
Cash Flow: $510,267
Details
Your Opportunity to Own a Thriving Ophthalmology
Kent County, MI

Established in 1998, this well-respected ophthalmology practice specializes in glaucoma and cataract treatments, serving a loyal patient base of over 3,000. With a strong referral network and an aging population driving demand, this practice presents significant growth potential. Operating with low...

$1,199,000
Cash Flow: $675,963
Details
Well-Established Diagnostic Imaging Business
Oakland County, MI

This well-established diagnostic ultrasound practice, licensed as an Independent Diagnostic Testing Facility (IDTF) since 2009, offers a strong foundation with consistent referral volume and a diversified payer mix. The practice performs approximately 160–190 imaging studies per month, operating across...

$169,000
Cash Flow: $90,847
Details
GYN-Only Women’s Health Practice
Shelby County, TN

This long-established, highly profitable women’s health clinic presents an outstanding opportunity for a strategic buyer, physician group, or private equity-backed platform. With over 17 years of trusted care in a high-income suburb of a major Southeastern metro, this GYN-only practice boasts a loyal...

$1,689,000
Cash Flow: $410,476
Details
Optometry Practice For Sale Grossing $900K
San Bernardino County, CA

Grossing $900K with doctor hours of 4 days a week (no Saturdays!) , this office has tremendous growth potential. Located in the Inland Empire just an hour from the Los Angeles and Orange County -- “ Nestled against the beautiful San Bernardino Mountains this practice offers an ideal business and residential...

On Request
Details
San Diego Optometry Practice Grossing almost $700K
San Diego County, CA

Great optometry practice with excellent net profit. Established over 40 years, this office boasts a strong adjusted net (before doctor wages) of almost $200,000 in 2022 on sales of $665,000. Revenue has been stable through the years. The office is 1,500 sq ft and includes 2 exam rooms, contact lens...

On Request
Details

Tips for Buying Medical Practices In US

Understand Regulatory & Compliance Requirements

When considering the purchase of a medical practice in the US, it is crucial to familiarize yourself with the numerous regulatory and compliance issues that govern healthcare businesses. Medical practices must adhere to strict federal, state, and local laws, including HIPAA regulations, fraud and abuse laws (such as Stark Law and Anti-Kickback Statute), and state licensing requirements. Before making an offer, consult with specialized healthcare attorneys and compliance experts to conduct due diligence and ensure the practice is fully compliant. Overlooking this step can lead to costly fines or even loss of operational licensure.

Evaluate Financial Performance & Growth Potential

Thoroughly analyze the financial statements of the medical practice, including revenue, expenses, outstanding liabilities, and receivables. Look for trends in patient volume, payer mix (private insurance, Medicare, Medicaid), and referral sources. It’s also important to determine whether the practice has opportunities for growth, such as expanding services, entering new markets, or adding providers. A detailed financial assessment with the help of accountants who understand medical practices will clarify the true value of the business and help you negotiate a fair purchase price.

Assess Transition and Patient Retention Risks

Purchasing a medical practice involves more than just acquiring assets; maintaining patient relationships and staff continuity is essential for long-term success. Plan for a well-structured transition period, ideally with the seller’s involvement, to reassure patients and staff during the change of ownership. Develop strategies to retain key employees and ensure smooth operational handover. Pay special attention to the potential for patient attrition and what contractual measures (such as non-compete or non-solicitation clauses) are in place to mitigate these risks. A careful transition plan will protect your investment and set the stage for future growth.