Middle-Market Businesses for Sale in the U.S.
Discover top middle-market businesses for sale in the United States on DealStream, the leading online marketplace for established companies. Browse hundreds of vetted listings—spanning manufacturing, services, tech and more—with detailed financials, proven cash flow and growth potential. Whether you’re an aspiring entrepreneur or seasoned investor, our intuitive search filters help you buy middle-market businesses that match your criteria. Start your acquisition journey today and unlock high-value opportunities!
Showcased Deals
Rolex & Jewelry Sales/Service Loaded w/ Inventory
This well-established, full-service jewelry store has been serving a loyal, multi-generational customer base for nearly four decades. The business has built an outstanding reputation for quality products, skilled craftsmanship, and honest, personalized service. It offers a comprehensive range of...
Luxury Concrete Design Construction Co.
Renowned, respected, 50-year Concrete Finishing business located in Scottsdale, Arizona. Founded in 1974, this company has built a high-quality long-standing reputation for concrete design and finishing, within the Golf Course and Resorts sector. The business has long-standing repeat clients, offering...
Highly Profitable Texas Pharmacy
High volume and very profitable pharmacy specializing in specific disease states. This pharmacy has been in business for over five years with continued growth. All major PBM contracts in place through PSAO. Fully staffed and easily operated by an absentee owner. Direct contracts with many pharma manufactures....
All Matching Deals
NE USA Based Part 135 Charter Business with Fleet
Full/Standard FAA Approval allowing for unlimited aircraft, pilots and aircraft types. This is a "turnkey" cash generating charter machine. Complete with company owned Pilatus PC12s and managed Pilatus PC12, totaling 4 aircraft managed. Comes complete with training program, pilot teams, DO/DM/CP...
Texas Specialty Pharmacy Operation - two locations
Well run pharmacies with a full staff (including pharmacists, technicians, and customer service reps) who would stay on post transaction. Pharmacies are currently absentee run, making this the perfect opportunity for a buyer looking to add a pharmacy to their portfolio. Seller is looking for a buyer...
Highly Profitable Texas Pharmacy
High volume and very profitable pharmacy specializing in specific disease states. This pharmacy has been in business for over five years with continued growth. All major PBM contracts in place through PSAO. Fully staffed and easily operated by an absentee owner. Direct contracts with many pharma manufactures....
Ohio Pharmacy
Very high-volume specialty pharmacy that has been in business for four years with continued growth. All major PBM contracts in place through PSAO. Fully staffed and easily operated by an absentee owner. Direct contracts with many pharma manufactures. Established Prior-Authorization P&P. Pharma voucher...
Illinois Specialty Pharmacy
Profitable specialty pharmacy with continued growth. Fully staffed and easily operated by an absentee owner. Direct contracts with many pharma manufacturers. All major PBM contracts in place through PSAO. Established Prior-Authorization P&P. Pharma voucher program contracts are also in place. Annual...
Travel & Mobile Accessories Brand / $40M+ in sales
This is a rare opportunity to acquire a profitable, IP-rich consumer lifestyle brand operating at the lucrative intersection of the $9.9T travel industry and the high-demand mobile accessory sector. With over $40 million in lifetime revenue, numerous patents for their product designs, and high-profile...
67 yr old Plumbing Co; $4.1M Rev, $1.3M Net
Highly Profitable, Long-Established Plumbing & Heating Contractor – Nassau/Suffolk, NY A rare opportunity to acquire a 67-year-old plumbing, heating, and remodeling contractor serving Nassau and Suffolk counties. This business operates from a strategically located 4,500 sq. ft. facility in Nassau...
Full-service Accounting/Tax preparation Business
Full-Service Accounting, Tax Preparation, and Insurance Business – Miami-Dade County This well-established firm offers comprehensive accounting, tax preparation, and property & casualty insurance services. The company provides a wide range of offerings, including: Personal and corporate tax return...
Profitable NY/NYC MBE-Certified Remediation Firm
Profitable NY/NYC MBE-Certified Environmental & Demolition Contractor – $10M+ Revenue, Strong Backlog, Blue-Chip Clients. Established New York–based environmental remediation and specialty contracting firm with over 13 years of proven performance, holding Minority Business Enterprise (MBE) certification...
Nationwide B2B Pharmacy Tech Marketplace
High-Margin, Nationwide B2B Pharmacy Tech Marketplace (Asset-Light, Rapid Growth). A fast-growing B2B online marketplace in the regulated healthcare space is now available for confidential acquisition. The platform connects licensed buyers and sellers nationwide, offering an easy-to-use, compliance-oriented...
Alaska Home Care Agency
Home Care agency Based in Alaska Providing Non Skilled Home Care Payer sources- LTC, Private Pay, VA
Luxury Concrete Design Construction Co.
Renowned, respected, 50-year Concrete Finishing business located in Scottsdale, Arizona. Founded in 1974, this company has built a high-quality long-standing reputation for concrete design and finishing, within the Golf Course and Resorts sector. The business has long-standing repeat clients, offering...
25 yr NY Waste Management, $11M rev, $1.25 EBITDA
Confidential sale of a Premier Independent, long‑established, NYC‑based roll‑off and carting company serving the NYC metro area. This asset‑heavy, platform provides dumpster, debris removal and recycling services to New York’s most prominent general contractors and key city agencies. The business is...
Tobacco Manufacturing Factory
Fully operating, Large 80,000 sq ft building with offices, factory production floor, warehouse, loading docks in the heart of NC tobacco country on approx 10 acres of land. Multiple high speed tobacco product lines capable of making and packing cigarettes, little cigars, cigarillos etc. appraised...
Fast Growing PK-6th with Real Estate
This innovative Preschool and Elementary was established in 2022 with the purchase of a 37,000 SF building on 1.5 acres. The building was completely renovated and has the capacity for up to 444 students. The campus features large, bright classrooms, an Indoor playground and a courtyard playground...
Profitable Montessori Schools with Real Estate
*This esteemed Montessori School has been catering to young students for more than 6 decades. *The sale includes real property with beautiful grounds in excess of 2.5 acres plus multiple buildings. *Three campuses (1 owned and 2 leased) that provide an ideal learning environment. *Enrollment of...
Profitable Montessori Schools with Real Estate
Prestigious Montessori educational facility with three campuses. Located on the east coast for over six decades, this institution has been synonymous with excellence in Montessori education. Situated in a prime location, this educational facility boasts state-of-the-art Montessori classrooms plus 2.5...
Midwest Construction Equipment Rental Business
This well-established equipment rental company has built a strong reputation over multiple generations as a trusted provider for both residential and commercial markets. Originally founded as a local retail operation, the business successfully transitioned into tool and equipment rentals, leading to...
Luxury Home Builder and Developer
Founded in 2001 with numerous awards, accolades, magazine articles, and news coverage, Luxury Home Builder and Developer is the one of the top luxury homebuilders in Scottsdale, successfully completing over 500 custom home and development projects, totaling over $1billion in value and counting. These...
Florida Retail Pharmacy
This pharmacy has strong community ties and is located in the prime location with quick access to all major local highways. Clean books, licenses and contracts. The pharmacy has an overwhelmingly positive reputation among physicians and patients alike. The pharmacy is equip with top of the line software...
Established Cutting-Edge Software, R&D, & Digital
Business is a cutting edge telecommunications, data science, and internet infrastructure lab that also provides technology staffing services and consultants. We have architects, developers, and analysts on 3 continents with clients and production operations in over 100 countries and 35 supported...
Major Internet Infrastructure Provider Partner Cap
The communications protocol that is the underpinning of the Internet was designed with two vital defects. 1. An unpreventable and inevitable bottleneck. 2. A whack-a-mole security defect. For this reason, fortune 1,000 companies have been driven to invest in more secure private networks (MPLS)....
Profitable, Vertically-Licensed NY Cannabis Co.
This is a confidential offering to acquire a premier, next-generation cannabis CPG and cultivation company already dominating the New York market. With over $6M in sales since April 2023 , placement in 85+ NY dispensaries , and a full suite of cultivation, processing, and distribution licenses, this...
Well-established Specialty Pharmacy For Sale
Founded in 2004, this pharmacy has built a strong reputation and a loyal customer base. With contracts with all major insurance carriers and a 340B license, this business offers a seamless transition for an experienced operator or investor looking to enter or expand within the specialty pharmacy sector. The...
Branded Hair Loss Ecommerce Treatment Products
The Company operates as a consumer retail business focused on providing hair concealment and haircare solutions through a combination of e-commerce and marketplace channels. It manages a lean in-house team primarily for fulfillment while outsourcing key marketing and digital functions to agencies. Manufacturing...
Tips for Buying A Middle-Market Business In US
Understand the Market and Prepare Thoroughly
Before making any moves, invest time in market research specific to your industry of interest and the broader economic climate. Middle-market businesses often have more complex structures, customer bases, and operational challenges compared to smaller firms. Familiarize yourself with recent trends, valuation multiples, and competitive dynamics. Assemble a team of experienced advisors—including a business broker, attorney, and accountant—who specialize in middle-market transactions. Being well-prepared gives you confidence during negotiations and helps you avoid potential pitfalls.
Conduct Rigorous Due Diligence
Due diligence is crucial to uncover the true health and risk profile of any target business. Go beyond surface-level financial evaluations by digging into tax records, employee contracts, supplier agreements, customer relationships, and any legal or regulatory issues. Review the company’s operations, analyzing its strengths, weaknesses, and reliance on key individuals. Ask for detailed explanations of any unusual transactions or inconsistencies. A meticulous due diligence process helps you validate the business’s value and flag any deal-breakers before you proceed.
Plan for Integration and Post-Sale Success
Buying a middle-market business isn’t just about closing the deal—it’s about what happens afterward. Start preparing your post-acquisition integration strategy early, focusing on retaining key employees, maintaining customer relationships, and ensuring business continuity. Develop a clear communication plan for internal and external stakeholders. Outline your growth and operational improvement initiatives. By planning your integration in advance, you maximize your chances of a smooth transition and long-term success with your new business.
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