California Medical Laboratories for Sale | Prime Business Listings
Buy a medical laboratory in California – explore exclusive listings of turnkey medical labs for sale across the Golden State. Whether you’re targeting a clinical diagnostics facility in Los Angeles, a biotech research center in the Bay Area, or a specialty testing lab in San Diego, our curated marketplace showcases modern equipment, established client bases, and transparent financials. Ideal for investors and entrepreneurs aiming to enter California’s booming healthcare sector, these acquisition opportunities deliver strong ROI and long-term growth potential. Browse now to find your perfect medical lab investment in California.
All Matching Deals
Clean High-Complexity CLIA+Medicare Shell for Sale
-Clean High-complexity CLIA with active Medicare for sale in Los Angeles County. -Shell is one year old, S-Corp, single owner. -Medicare has active bank account connection and was never billed (no audit risk). -Lab is located in Torrance, Los Angeles county, however we prefer the buyer to move the...
Clinical Laboratory, netting 1M/month
Broker is pleased to offer an extraordinary opportunity to all major investors in the laboratory industry. Seller owns and operates laboratories in California, and multiple other states are offering opportunities for sale, partnership, investment, mergers, or acquisitions (partial purchasing is also...
2M+ Net Full-Service Lab, Employees, Customers
Business Investment is pleased to present opportunity to acquire a profitable, full-service high-complexity clinical laboratory located on the border of Los Angeles and Orange Counties. With more than $2M in net income, this laboratory offers a stable customer base, transferable provider contracts,...
San Diego Clinical Lab, 2.4M Gross, 1M Net
Broker is pleased to present the opportunity to acquire a profitable, full-service high-complexity clinical laboratory located in San Diego, California. • Established: 2019 • Specialties: Pharmacogenomics (PGx), Molecular Diagnostics with MolDx Z Code (Mental Health, Pain Management, Cardiovascular),...
California High Complexity CLIA, CAP, Medicare, Me
Fully licensed high-complexity CLIA-certified clinical laboratory with CAP accreditation, Medicare, and Medi-Cal provider status. This turnkey operation offers a rare opportunity for immediate activation or relocation to the buyer’s preferred site. Price: $525,000. Established: 2025 Certifications:...
California High Complexity CLIA, Validated PCR Equ
High-complexity CLIA-certified clinical laboratory with new accreditation, valid 2 full years. This turnkey operation offers a rare opportunity for immediate activation or relocation to the buyer’s preferred site. Price: -$120,000 CLIA only, OR -$250,000 with location and validated PCR Equipment. Established:...
400K Net Absentee-Owner DME Business in California
Established 28 years, this fully licensed and accredited Durable Medical Equipment (DME) provider has built a long-standing reputation serving patients across California. The company supplies equipment designed to improve mobility, comfort, and quality of life, and has also developed proprietary, patented...
CLIA/CAP accredited, NGS PGS IVF testing
-Newly Accredited Oct 23, 2025 -Appeoved CAP Molecular Pathology checklists -Activities list approved for: NGS wet lab, NGS bioinformatics, DNA amplification and Extraction -Validated and approved to run NGS Preimplantation Genetic Test-Aneuploidy (PGT-A) -With options to add PGT-M, hereditary...
SoCal Lab, Medi-Medi, Staff, Equipment, Write-Off
Big, spectacular clinical laboratory, fully equipped for infectious diseases testing, chemistry, and toxicology, with active Medicare and Medi-Cal. Seller is motivated to any deal and note. Business can be purchased with very little down plus there is nearly 2M write off opportunity on corporate...
CLIA License High or Moderate Complexities
For sale is a California Laboratory CLIA license as an asset sale to lab professionals who need an activated CLIA license immediately. It comes with a state laboratory license and a medical director in good standing. There is no equipment or location to keep (unless negotiated extra). Asking for...
Lab with Big Customer List, PCR, Genetic, Equipped
High complexity CLIA with certificate of Compliance, in good standing, with Medical Director, Equipment, and big customers database. Medicare is active, however offered for transfer only. Lab is not serving accounts currently, due move out of state (as a pure software company) – however very active...
20M Growing Lab, Full Service, All In-Network
Broker is presenting a big, old, real full menu laboratory: all tests, all specialties, contracted with major insurances. Adding accounts and growing business daily. Tests nicely spread across all specialties, great reimbursements, where it counts. This is opportunity for investors with rolling...
30 yrs. lab, BC, BS, UHC, Health Net, Medi-Medi
Long-established laboratory with grandfathered in-network insurance contracts — including with major providers no longer extending such agreements to privately held labs. Location: Busy Medical Building in Los Angeles Valley | Gross Revenue: $1.2M/year | Net Profit: $300K/year Private PPO Contracts...
CA Laboratory with Medicare, Medi-Cal, Z-code
Broker is presenting an established clinical laboratory with California State Laboratory License, High-Complexity CLIA, Medicare and Medi-Cal, z-code, all necessary equipment. Laboratory is well equipped. Running currently UTI, all 4 Respiratory, GI, Wound and toxicology screenings. Equipment...
$20M+ Large Clinical Laboratory – Full Robotic
Broker is pleased to present a major clinical laboratory opportunity. Established in 2019, this laboratory operates as a fully automated, 24/7 facility with comprehensive insurance contracts and advanced infrastructure. • Robotic Automation: State-of-the-art equipment valued at over $25M, fully paid...
Laboratory with Medicare, 550K gross
Established clinical laboratory in Southern California, fully equipped for chemistry testing and operating for 2 years with an active Medicare contract. • Financials: Grossing ~$550,000 annually | Adjusted net available upon request • Facility: 1,400 SF | Lease $2,500/month (utilities included) |...
Over $8OK Cash Flow Part-Time Very Low Expenses
Still struggling to get your mobile phlebotomy business off the ground? Here’s the truth: Most phlebotomists fail to scale because they’re chasing patients one at a time, begging for referrals, and working endless hours… only to barely break even. What if you could skip the grind? I’m selling...
CLIA –Full Test Menu –Medicare Lab –Turnkey Ready
CLIA-Certified Medicare Lab – Turnkey, Profitable, Fully Operational Opportunity to acquire a fully licensed and operational CLIA-certified laboratory with active Medicare billing, strong infrastructure, and clean documentation. This lab is set up for immediate takeover and continued success. Highlights: • Medicare...
Fastest Labs Franchise Opportunity
Fastest Labs Franchise Opportunity – A Turnkey Investment Fastest Labs is a leading provider of drug, alcohol, and DNA testing services, specializing in fast, accurate, and reliable results for individuals and organizations. With a proven franchise model, Fastest Labs has become a trusted partner...
CLIA Laboratory with Medicare for Sale
CLIA Certification of Registration Licensed laboratory for sale that includes a BD Max (the most prominent machine for IVD moderate complexity FDA approved use) and a high complexity Quantstudio 12k FLEX. The laboratory comes with Medicare applied for and pending and is completely unbilled and ready...
CLIA with Compliance with Equipment for Toxicology
High complexity CLIA available for 100K. Optionally equipment for extra 90K (high quality and worth much more): -AB Siex Triple Quad 4500 -ExionLC controller -GENERATORRB PEAK SCIENTIFIC GENIUS 1024 -BACK UP BATTERY -Euroimmun EUROBLOTONE EVA 47664 -TUOHE MIX 200 -POWERGENE 9600 PLUS -ATILA...
California CLIA Waiver License
- clean california CLIA laboratory license - ready to relocate and start testing
Tips for Buying Medical Laboratories In California
Understand Regulatory Compliance
Buying a medical laboratory in California requires a thorough understanding of state and federal regulations. The laboratory must comply with the Clinical Laboratory Improvement Amendments (CLIA), California Department of Public Health (CDPH) licensing requirements, and potentially CAP accreditation if it serves certain markets. Buyers should conduct detailed due diligence to verify that all licenses, certifications, and permits are current and in good standing. Non-compliance can lead to hefty fines, operational delays, or even license suspension, so regulatory history and compliance records should be a top priority during the evaluation process.
Assess Operational Performance and Profitability
Take a close look at the laboratory’s financial statements and key performance indicators. Scrutinize revenue streams, billing practices, payer contracts (including insurance reimbursement rates), and patient volume trends. Check if the laboratory is diversified in its client base and test offerings, which reduces dependence on just a few clients or referral sources. Potential buyers should also analyze the lab’s operational efficiencies, technology infrastructure, and staffing model—these factors can significantly impact profitability, especially in California’s competitive lab services market.
Evaluate Reputation and Growth Potential
Reputation is critical in healthcare. Review online feedback, client testimonials, and any history of complaints or litigation. Relationships with referring physicians, hospitals, and other health providers are also key assets that drive ongoing revenue. Investigate the laboratory's standing in the community, then look for untapped market opportunities—such as expanding test menus, geographical reach, or new payer relationships. A laboratory with a strong reputation and obvious pathways for growth will provide the best long-term investment potential in the dynamic California medical market.
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