Explore Profitable Businesses for Sale in Collier County, FL
Discover the best Collier County businesses for sale in Southwest Florida’s booming market with DealStream. From established waterfront restaurants and retail shops in Naples and Marco Island to lucrative agricultural ventures in Immokalee, our curated listings feature pre-vetted, profitable opportunities backed by detailed financials. Whether you’re an investor seeking high-ROI assets or an entrepreneur ready to own your dream business, start your search today and unlock exclusive deals on Collier County’s top businesses for sale.
Showcased Deals
$600,000 Revenue – Naples, FL CPA Firm for Sale
*** THIS LISTING IS CURRENTLY SALE PENDING. *** Overview Broker represents this CPA firm located in Naples, FL. The owner is willing to continue working for the buyer for several years on a part-time basis to assist in client retention. The buyer of this firm must be a CPA. The Firm The firm...
Very Profitable Retail & Compounding Pharmacy
Legacy retail and non sterile compounding pharmacy in Prime West Coast Florida location. 15 years established in a beautiful, prestigious and affluent community in sunny South West Florida. The original and current pharmacist/ owner has built an outstanding name and recognition both in the community...
Men's Barber Shop & Spa Chain with 4 locations
Extremely Profitable Men’s Barber Shop & Spa Chain with Four Prime SW Florida Locations This successful chain operates four corporate-owned stores strategically located in top Southwest Florida markets. Offering a full range of services including haircuts, beard shaves, nail care, massages, waxing,...
All Matching Deals
Men's Barber Shop & Spa Chain with 4 locations
Extremely Profitable Men’s Barber Shop & Spa Chain with Four Prime SW Florida Locations This successful chain operates four corporate-owned stores strategically located in top Southwest Florida markets. Offering a full range of services including haircuts, beard shaves, nail care, massages, waxing,...
Solo General Practice with Insurance Contracts
Established solo general practice clinic located in Naples, Florida. The physician is seeking an immediate sale and is open to all reasonable offers. The clinic is credentialed with major insurance providers including Blue Cross Blue Shield, Medicare, Medicaid and UnitedHealthcare. It operates out...
Very Profitable Retail & Compounding Pharmacy
Legacy retail and non sterile compounding pharmacy in Prime West Coast Florida location. 15 years established in a beautiful, prestigious and affluent community in sunny South West Florida. The original and current pharmacist/ owner has built an outstanding name and recognition both in the community...
$600,000 Revenue – Naples, FL CPA Firm for Sale
*** THIS LISTING IS CURRENTLY SALE PENDING. *** Overview Broker represents this CPA firm located in Naples, FL. The owner is willing to continue working for the buyer for several years on a part-time basis to assist in client retention. The buyer of this firm must be a CPA. The Firm The firm...
$520k Rev Naples, FL - Accounting & Tax Firm
*** THIS LISTING IS CURRENTLY SALE PENDING. *** OVERVIEW Broker represents this Accounting & Tax practice located in Naples, FL. The seller is willing to provide transitional assistance to the buyer to help ensure client retention. THE PRACTICE The practice has significant monthly recurring...
Naples FL Full Service Landscape Company NET $1M
The owner has owned the company 40 years and is looking to retire. They do lawn service, landscape renovation, tree trimming and irrigation service. The business is fully staffed with approximately 37 employees. Most of their clientele is high-end residential. They also do commercial work. The Naples...
Premier SWFL Landscape & Lawn Care
The business offers a comprehensive suite of landscaping and property maintenance services, including landscape design and installation, lawn maintenance, and irrigation and sprinkler systems repair and maintenance throughout Collier and Lee Counties. The business features an experienced team of trained...
Scalable Post-Harvest Product Manufacturer/Distrib
An exceptional opportunity to acquire a turnkey leading post-harvest product manufacturer and distributor in a specialized niche with widespread international demand. Highlights: • Over 20% growth over the past two years • Rapid revenue growth from international channels • Strong brand reputation...
Medical Practice
This established integrative medical practice in Collier County, Florida has served a highly affluent and health-focused population for more than two decades. The business operates through a diversified cash-pay model supported by advanced diagnostics, wellness programs, and a significant base of specialized...
Health and Wellness Centre in Key Medical District
Uniquely combined traditional and holistic full scale wellness centre positioned for growth in very strong market Prime location - in Naples medical district Runs semi-absentee with trained staff in place Capacity to grow – ability to increase by at least 50% with added hours, days and practitioners E2...
Commercial Printing and Graphic Design Business
Long-established commercial printing and graphic design business serving Collier County since 1980. For many decades, the company has operated as a foundational print provider in Southwest Florida, producing high-quality print collateral, marketing materials, promotional items, and specialty finishing...
Mobile Pet Grooming Services - Home Based
An excellent opportunity to acquire a well-positioned mobile pet grooming business serving the affluent and pet-loving communities of Southwest Florida. This owner-operated business specializes in on-site grooming, offering a stress-free alternative to traditional grooming salons. With a flexible, low-overhead...
Premier Roofing Repair in Booming SW Florida
Description: Step into Florida’s high-demand roofing sector with a business built on many years of trust, safety, and exceptional craftsmanship. This business operates in a recession-resistant niche, delivering specialized roof repair services for residential properties across clay tile, architectural...
Door Contractor Business
Unique opportunity to buy a DOOR Contractor Business. This door Hardware Specialist does installations, repairs, sales, rekeying, lockouts for county officials, general contractors, property management companies, HOAs and commercial businesses, plus much more. Work includes commercial hollow metal doors...
Floor Covering Retail and Distribution Business
Long-established specialty flooring retailer with a strong brand reputation and consistent cash flow, positioned for continued growth in a high-income coastal market. The company has built an enviable reputation for quality craftsmanship, personalized service, and premium flooring products. With many...
Full-Service Auto Repair & Maintenance Shop
A highly rated, family-owned, full-service auto repair and maintenance shop in Naples, Florida, known for its honest, affordable, and dependable service, especially on older model vehicles. The shop has served the local for over 35 years and is a NAPA Auto Care Center (too much information?) and AAA...
Food Distributor
This is an Italian food broker business. The Seller is ready to pass the baton to a new owner. The Company was founded in 1987 importing olive oils, balsamic vinegar, pasta and tomatoes to supply chain restaurants through the foodservice trade. After years of tremendous growth in this market they quickly...
Established, Profitable, SBA PreApproved Clothing
Great opportunity to purchase a well-established business that is SBA pre-approved and situated in a fantastic location in Naples • Established 25+ year business that sells clothing & accessories • Consistent revenue generating business, over $900,000 a year in sales • Very healthy SDE 3-year average...
Aesthetics Dermatology Practice in SW Florida
For Sale: Opportunity to acquire a leading aesthetics dermatology practice located in Southwest Florida with a history of strong profitability, powerful brand recognition, and recurring patient base. Practice generated revenues of ~$3 million with a ~20% historical adjusted EBITDA margin. • A 30+ year-old...
Well Known Designer Consignment Shop Premium Local
Location, location, location! This shop is in the most premium spot to deliver great sales due to organic foot traffic and high volumes of seasonal tourism. The shop has over 700 consignees and loyal customers. Very well known and sought after for the great product line of like-new and authenticated...
Insulation Contractor
PRICE REDUCED! This company specializes in spray foam insulation and is located in Southwest Florida, one of the busiest and most exclusive housing markets in the United States. Clients include some of the largest General Contractors for both commercial and residential projects, along with individual...
Established Marine Construction Company
A well-established marine construction business based in Southwest Florida, specializing in high-quality seawalls, docks and boat lifts. Known for their clean job sites and personalized service, they’ve built a strong reputation for craftsmanship, timely project completion, and customer satisfaction....
Naples, Florida, Practice for Sale
26 year Chiropractic Wellness 'cash practice' collecting $179,917.00. Open 5 'half days' weekly. This is a beautiful 'remodeled' [high visibility] practice close to the beaches and popular sites. Upscale 'health conscience' community with expendable income. Current DC reluctantly retiring & moving closer...
New Price Window Treatment Business in SW Florida
Take the helm of one of Southwest Florida’s most respected design brands. With 7 years of consistent success, this turnkey business offers immediate profitability and prime positioning in Florida’s booming luxury home market. Location & Market Advantage Serves Naples, Marco Island, Estero, and...
Absentee Owner Hair Salon
Very successful franchise Established in 2018 Absentee owner and well-established location, with a solid customer base Perfect for E2 visa, Salon is in excellent location in a high-traffic areas (Publix shopping center) A franchise name you can trust, a business you can believe in. As an established...
Tips for Buying A Business In Collier County, FL
Conduct Thorough Local Market Research
Before making any purchase, investing time in understanding the unique characteristics of the Collier County market is essential. Research demographic trends, tourism patterns (especially in Naples and Marco Island), and any industries showing growth within the region. This foundational knowledge will help you pinpoint opportunities and avoid sectors that may be in decline locally. Pay attention to seasonal population shifts, as these can greatly influence sales and staffing needs throughout the year.
Review Legal and Regulatory Considerations
Collier County and the state of Florida both have specific licensing, zoning, and business regulations that buyers should thoroughly review. Engage with local advisors—including a real estate attorney and a CPA familiar with Florida businesses—to ensure the target company is compliant with all county and state codes. Don’t overlook permits, environmental restrictions (especially near coastal areas), and the transferability of any existing business licenses.
Evaluate the Existing Workforce and Relationships
Many businesses in Collier County rely heavily on skilled employees and long-standing relationships with suppliers and the local community. During due diligence, evaluate the stability, experience, and satisfaction of the current workforce. Also, investigate the reputation of the business among residents, tourists, and local vendors. Retaining key employees and strong business relationships can be the difference between a smooth transition and a challenging first year of ownership.
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