Discover Pharmacies & Drugstores for Sale Across the USA
Discover an extensive selection of pharmacies and drug stores for sale across the United States on DealStream, the leading online marketplace for pharmacy businesses. Browse pharmacy businesses for sale—from independent drug stores and compounding pharmacies to franchise outlets and high-traffic retail locations—each listing complete with detailed financials, asking prices, and growth projections. Whether you’re looking to buy a turnkey pharmacy with loyal clientele or expand your healthcare portfolio, our curated listings make it easy to find profitable, investment-ready opportunities. Start browsing now to seize your ideal pharmacy acquisition and capitalize on the booming U.S. healthcare market.
Showcased Deals
Established North TX Pharmacy - Price Reduction
Price Reduced! - Established Profitable Texas Pharmacy with Real Estate Location: Between 30 and 60 minute drive northwest of of Fort Worth Sales: $2,800,000 Volume: 48,000 scripts (190/day) Gross Profit: $580,000 Seller's Discretionary Earnings (SDE): $369,000 Inventory: $200,000 Real Estate:...
Well-Positioned Retail Pharmacy
This well-positioned retail pharmacy is located in a busy strip center with excellent visibility and traffic, surrounded by medical offices, clinics, and a hospital. The site has been carefully designed for dispensing efficiency, with most of the space dedicated to pharmacy operations and a manageable...
Texas Retail Pharmacy
Great opportunity to acquire a long standing pharmacy with clean licenses and contracts. The pharmacy must be moved as the lease cannot be renewed. Licenses, contracts, FF&E and files are included. The inventory value will be taken on the day of transfer but is currently estimated to be 60k. Annual...
All Matching Deals
Texas Specialty Pharmacy Operation - two locations
Well run pharmacies with a full staff (including pharmacists, technicians, and customer service reps) who would stay on post transaction. Pharmacies are currently absentee run, making this the perfect opportunity for a buyer looking to add a pharmacy to their portfolio. Seller is looking for a buyer...
Highly Profitable Texas Pharmacy
High volume and very profitable pharmacy specializing in specific disease states. This pharmacy has been in business for over five years with continued growth. All major PBM contracts in place through PSAO. Fully staffed and easily operated by an absentee owner. Direct contracts with many pharma manufactures....
Texas Pharmacy
This pharmacy is fully staffed and easily operated by an absentee owner. Direct contracts with many pharma manufactures. Established Prior-Authorization P&P. Pharma voucher program contracts in place. Annual Sales $12,656,546.00 Gross Profit $1,239,635.60 EBITDA $559,528.00 Annual Rx Count 29081 Asking...
Ohio Pharmacy
Very high-volume specialty pharmacy that has been in business for four years with continued growth. All major PBM contracts in place through PSAO. Fully staffed and easily operated by an absentee owner. Direct contracts with many pharma manufactures. Established Prior-Authorization P&P. Pharma voucher...
Illinois Specialty Pharmacy
Profitable specialty pharmacy with continued growth. Fully staffed and easily operated by an absentee owner. Direct contracts with many pharma manufacturers. All major PBM contracts in place through PSAO. Established Prior-Authorization P&P. Pharma voucher program contracts are also in place. Annual...
Two Pharmacies in Ohio
Two profitable independent pharmacies. Current ownership is looking to retire but will be willing to assist during transition to ensure smooth transfer of ownership. Pharmacies are fully staffed and have a loyal customers in the communities that they serve. Opportunity is preapproved with a pharmacy...
Minnesota Community Retail Pharmacy
Well run retail community pharmacy. Currently services a local patients as well as hospice centers and assisted living facilities. Fully trained and efficient staff with clean contracts and licenses. Sellers are looking to retire and are ready to hand over the business to a buyer who knows the industry...
Texas Retail Pharmacy
Great opportunity to acquire a long standing pharmacy with clean licenses and contracts. The pharmacy must be moved as the lease cannot be renewed. Licenses, contracts, FF&E and files are included. The inventory value will be taken on the day of transfer but is currently estimated to be 60k. Annual...
Texas Pharmacy in DFW area
Great opportunity to purchase clean licenses, DEA Registration with clean contracts. Long standing pharmacy within the DFW vicinity. Pharmacy is well known in the community and has a great reputation. Sellers are looking to retire. Annual Sales $1,132,533.67 Gross Profit $309,515.42 EBITDA $26,649.00 Annual...
Twin Cities Community Pharmacy
Twin Cities area Pharmacy is fully staffed with well-trained employees. All major PBM contracts are in place and contracted directly whenever possible. This pharmacy has a loyal customer base. Pharmacy is available for either stock or asset transaction. Licenses and contracts are all in good standing. Owner...
Well-Positioned Retail Pharmacy
This well-positioned retail pharmacy is located in a busy strip center with excellent visibility and traffic, surrounded by medical offices, clinics, and a hospital. The site has been carefully designed for dispensing efficiency, with most of the space dedicated to pharmacy operations and a manageable...
Well-Established Retail Community Pharmacy
Well-Established Retail Community Pharmacy. Original owner with 11 years of steady relationships in the community. Located in high-end shopping center in central Palm Beach. Multiple Streams of revenue including Compounding, front end sales and legacy community relationships. Full compounding lab. Current...
Extremely Profitable Legacy Retail Pharmacy
Extremely profitable legacy retail pharmacy available as the long-time owner and pharmacist prepares for retirement. This turnkey operation is fully staffed, with an experienced pharmacist and support team already in place, ensuring seamless continuity for a new owner. The business has a loyal patient...
Very High Volume Retail / Closed Door Pharmacy
This well-established retail and long-term care pharmacy represents a premier opportunity in Miami-Dade County's healthcare sector. With over 18 years of continuous operation, the business has achieved recognition as a market leader in assisted living facility (ALF) and long-term care servicing throughout...
Community Retail Pharmacy For Sale
Fully licensed community retail pharmacy for sale, offering all major PBM contracts, a convenient drive-through, non-sterile compounding room, and two private consulting rooms. This turnkey operation comes with a profitable homeopathic e-commerce website, established sales, and dedicated homeopathic...
Florida Pharmacy
Profitable pharmacy with further growth potential. The pharmacy is well run and fully staffed. Seller believes that all staff (including the PIC) would stay on post transaction and would be happy to work for the Buyer. Pharmacy is currently operated by an absentee owner. Clean licenses and contracts...
Florida Retail Pharmacy
This pharmacy has strong community ties and is located in the prime location with quick access to all major local highways. Clean books, licenses and contracts. The pharmacy has an overwhelmingly positive reputation among physicians and patients alike. The pharmacy is equip with top of the line software...
Nevada Retail Pharmacy
This pharmacy in southern Nevada has had the pleasure of serving the community for over 3 years. Pharmacy fills all scripts but has a specialty in neurology. Owner is looking to retire from pharmacy ownership and is looking for a buyer with pharmacy background to take over the pharmacy and carry on...
Pharmacy in Pennsylvania
Busy and profitable retail pharmacy in Central Pennsylvania. This pharmacy has been in business for over 20 years and has annual sales of $7.5 Million and fills over 107,000 prescriptions per year. There is approximately $350,000 in prescription inventory and $25,000 in front end inventory. LTC is...
Established Florida Pharmacy W/ Excellent Growth
Community pharmacy filling 1,000+ scripts per week with 3,900+ active patients. Strong Medicare and commercial mix, 80% generic, automation in place, and experienced staff. Clean compliance record, affordable rent ($3K/mo.) in a 2,500 sq ft facility, and non-sterile compounding with statewide shipping....
Pharmacy with All Insurance Companies and Licenses
Established Retail Pharmacy. Original Owner / Operator Pharmacist (RPh). No pending audits with third parties or DEA (Full 2-5). Has all direct Insurance Contracts: CVS/Caremark, Express Scripts, Humana, Optum, Prime Therapeutics. Medicare & Florida Medicaid Provider Numbers. PSAO is AlignRx. Software...
Well-established Specialty Pharmacy For Sale
Founded in 2004, this pharmacy has built a strong reputation and a loyal customer base. With contracts with all major insurance carriers and a 340B license, this business offers a seamless transition for an experienced operator or investor looking to enter or expand within the specialty pharmacy sector. The...
Specialty Pharmacy. Turnkey Operation. Niche Focus
Closed Door Specialty Pharmacy specializing in servicing hospice patients at home and in assisted living facilities throughout Miami-Dade and Broward Counties. Prescriptions are received electronically, processed in real time through special third party insurance, and delivered daily by three contracted...
Very Profitable Retail & Compounding Pharmacy
Legacy retail and non sterile compounding pharmacy in Prime West Coast Florida location. 15 years established in a beautiful, prestigious and affluent community in sunny South West Florida. The original and current pharmacist/ owner has built an outstanding name and recognition both in the community...
Turnkey Retail Pharmacy. Insurance Contracts.
Great opportunity to purchase a Turnkey retail Health Mart pharmacy with CVS / Caremark and Express Scripts insurance contracts in place. Located in a busy shopping plaza that is anchored by a well-known Supermarket plus many other service and related businesses that drive traffic to the center. Professional...
Tips for Buying Pharmacies and Drug Stores In US
Understand Regulatory and Licensing Requirements
Before proceeding with the purchase of a pharmacy or drug store, it is crucial to thoroughly understand and comply with all federal, state, and local regulations. Pharmacies are heavily regulated by agencies such as the DEA, FDA, and state Boards of Pharmacy. Ensure that the business holds current licenses, is in good standing, and there are clear procedures for transferring these licenses. Consulting with a legal expert who specializes in pharmacy law will help you navigate compliance, avoid costly fines, and ensure a smooth transition.
Evaluate Contracts and Third-Party Relationships
Pharmacies often rely heavily on third-party relationships, including pharmacy benefit managers (PBMs), insurance providers, and suppliers. Review all existing contracts for reimbursement rates, terms, and potential red flags such as pending disputes or unfavorable clauses. Confirm that key contracts, especially with PBMs, are transferable and understand how the sale may impact reimbursements or relationships. This due diligence will help maintain consistent revenue streams and avoid post-sale surprises.
Assess Location, Demographics, and Competition
The success of a pharmacy or drug store often hinges on its location and the demographics it serves. Analyze the foot traffic, proximity to hospitals or clinics, and customer base, as well as local population trends and health needs. Consider the density and quality of competing pharmacies in the area. Additionally, evaluate the store’s reputation and its niche—such as compounding, specialty medications, or DME (durable medical equipment). Understanding these dynamics will help you ensure the long-term profitability and sustainability of the business.
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