San Mateo County Businesses for Sale – Prime California Opportunities

Discover the most comprehensive selection of San Mateo County businesses for sale on DealStream. Whether you’re seeking a thriving restaurant in Redwood City, a tech startup in Foster City, or a retail store in Millbrae, our up-to-date listings connect buyers and sellers throughout Silicon Valley. Benefit from detailed financials, professional broker support and exclusive off-market opportunities. Start browsing now to find your ideal business for sale in San Mateo County and turn your entrepreneurial vision into reality.

All Matching Deals

Florist Business
San Mateo County, CA

Iconic Floral Retailer with Close to a Century of Excellent Service When it comes to excellence in flowers and plants for personal, corporate, or event purposes, this retail florist stands far above the rest. Located on the San Francisco Peninsula, they deliver to the whole Bay Area, especially San...

$2,200,000
Details
Towing and Repair Company
San Mateo County, CA

This extremely well-established towing and repair company offers a unique advantage with an automated customer acquisition system with exclusive AAA contract, ensuring a steady flow of business without heavy reliance on manual outreach. The company provides 24/7 towing services, auto repair, vehicle...

$720,000
Cash Flow: $233,000
Details
Glass Installation and Service
San Mateo County, CA

This well-established glass business has been serving residential and commercial customers since 1976. Specializing in window and frame replacements, custom glass, and repairs, it benefits from a loyal local customer base and steady inbound demand. The operation is lean and efficient, with low overhead...

$220,000
Cash Flow: $79,355
Details
Redwood City, CA

For Sale - Equipment Rental Business - Redwood City, CA. 94063 Providing Quality Rental Equipment to the Mid-Peninsula Since 1987. Redwood Rental is an Equipment Rental yard that has been serving contractors, for over 36 years. Full service Rental Yard caters to all types of customers, from homeowners,...

On Request
Details
Profitable Test Equipment Repair & Sales
Menlo Park, CA

This profitable and unique business offers upgrades, repairs, refurbishing and resale of critical semiconductor test equipment no longer supported by OEMs. With 32 years in Silicon Valley, the company has built strong relationships and goodwill with local suppliers and clients as well as overseas customers....

$675,000
Cash Flow: $246,495
Details
Turnkey Auto Body Paint Supply Business
San Mateo County, CA

This is a rare opportunity to acquire a profitable, turnkey automotive paint supply business located in San Mateo County. The business specializes in high-quality automotive paint products and supplies, offering expert color matching. Known for its outstanding customer service and strong relationships...

$649,000
Cash Flow: $221,350
Details
San Mateo County, CA

This profitable and unique business offers upgrades, repairs, refurbishing and resale of critical semiconductor test equipment no longer supported by OEMs. With 32 years in Silicon Valley, the company has built strong relationships and goodwill with local suppliers and clients as well as overseas customers....

$675,000
Cash Flow: $246,495
Details
Barre Studio Opportunity - Prime Location
Redwood City, CA

This boutique studio features over $90,000 invested in equipment and buildout, offering a modern, stylish environment with a strong, established brand identity. The business provides a mix of Barre, dance, yoga, and Zumba classes, including senior-friendly options, with flexible membership plans such...

$150,000
Details
Your Concept Your Opportunity
San Mateo County, CA

There, on the sun-drenched corner, stands 4,700 square feet of pure possibility—walls of glass from floor to ceiling, drinking in California light like a ’47 Cheval Blanc takes in candlelight. Every passerby on the street below becomes an unwitting extra in the opening scene of your legend. Inside,...

$750,000
Details
European Market with Liquor License in East Bay
San Mateo, CA

This European market and café is situated on a prominent thoroughfare in East Bay. The business offers pantry items, groceries, coffee, pastries, ice cream, milkshakes, and more. It features an assortment of unique imported goods from Europe, presented on metal racks to create an authentic shopping...

$200,000
Cash Flow: $8,201
Details
San Mateo, CA

Exceptional opportunity to own a boutique general dental or Orthodontic facility in one of the Bay Area’s most desirable and affluent communities. Located in the heart of San Mateo, this well-established office offers a unique blend of high-quality technology and equipment in an upscale environment...

$349,000
Details
San Mateo County, CA

Fully established and long-standing business serving the community as a one-stop shop for shipping, mailbox rentals, printing, and essential business services. Known for reliability and trust, this store has built a strong reputation with both individual and commercial clients who rely on its convenience...

$400,000
Cash Flow: $154,381
Details
Profitable Vacuum and Sewing Service Center
San Mateo County, CA

Well-established business serving the San Francisco Bay Area since 1978. Business specializes in the sales and service of vacuum cleaners and sewing machines, the center offers a wide selection of products, including new and refurbished vacuums, cleaning supplies, replacement parts, and sewing machines...

$175,000
Cash Flow: $68,864
Details
Redwood City (S.F. Bay Area), Practice for Sale
Redwood City, CA

13-year acupuncture office collecting $113,462.00. Ideal location. Plenty of room for continued growth. This beautiful community thrives on alternative approach to health & wellness and has the expendable income to maintain such a quality of life. Excellent insurance coverage for employees of some of...

On Request
Details
For Sale: Pediatric practice in Half Moon Bay, CA
Half Moon Bay, CA

For Sale: Pediatric practice in Half Moon Bay, CA. This is an established and known practice in the community with average collections of $450,000 a year. Half Moon Bay is a small city on the California coast, south of San Francisco and a short drive to San Mateo an upscale city on the peninsula. A...

$450,000
Details
Redwood City (S.F. Bay Area) Practice for Sale
Redwood City, CA

13-year acupuncture office collecting $113,462.00. Ideal location. Plenty of room for continued growth. This beautiful community thrives on alternative approach to health & wellness and has the expendable income to maintain such a quality of life. Excellent insurance coverage for employees of some of...

On Request
Details
Half Moon Bay-Integrative Family Health Practice
Half Moon Bay, CA

For Sale: Integrative Family Health Practice in Half Moon Bay, CA, 94019. This is an established, and known, practice in the community for 15 years, as a hub for those seeking Fertility Assistance, Prenatal, postpartum, parenting education and support. Averaging collections of $75,000./year. This...

$75,000
Details
Mediterranean Market, Deli, Bakery & Halal Food
San Mateo County, CA

A rare opportunity to acquire A HIGH-VOLUME Successful Gourmet Market located on a busy street in San Mateo County. It was established in 1992 and current owner has owned it since 2006. In 2011 it was relocated to a newly Built out Facility nearby. The build out included: New Floors, Plumbing, Electrical,...

$1,500,000
Cash Flow: $315,529
Details
Premier Kids’ Fitness & Party Center
San Mateo, CA

Step into a turnkey business with a proven track record and strong brand presence! A vibrant, family-friendly children’s fitness, play, and party center that blends fun and wellness in a clean, safari-themed environment. This is a fantastic opportunity for an entrepreneur or investor seeking a profitable,...

$1,100,000
Cash Flow: $272,792
Details
Optometry Practice for Sale – California
San Mateo County, CA

CALIFORNIA OPTOMETRY PRACTICE FOR SALE – SAN MATEO COUNTY, CA Your eyes are not deceiving you…this is an extremely rare opportunity to buy a successful optometry practice in the greater SF Bay Area, grossing $2M per year, with a purchase price less than $1M! Located in San Mateo County, one of the...

$963,791
Details

Tips for Buying A Business In San Mateo County, CA

Understand the Local Market Dynamics

San Mateo County, situated in the heart of Silicon Valley, features a dynamic and competitive business landscape. Before making any decisions, invest time in comprehensively researching the local market trends, key industries, and demographic changes. Many successful buyers tap into the county's thriving tech, healthcare, and service sectors. Pay attention to existing competition, barriers to entry, and regional economic drivers, as these can significantly impact your long-term growth prospects and valuation.

Conduct Thorough Due Diligence

Due diligence is crucial to a successful acquisition. Carefully review financial statements, tax returns, and legal documentation to verify the business’s performance and uncover any hidden liabilities. San Mateo County businesses may encounter strict local regulations and zoning laws, so confirm that the business is fully compliant with municipal codes and licensing requirements. Don’t hesitate to engage local professionals—accountants, attorneys, and business brokers—to help scrutinize details and prevent costly oversights.

Evaluate Location and Growth Potential

The location of your chosen business within San Mateo County can greatly influence its traffic, revenue, and scalability. Assess proximity to highways, major employers, and public transportation, factoring in high real estate costs typical of this region. Look for opportunities where you can bring additional value, such as underserved customer segments or expansion potential. Having a clear plan for growth tailored to the unique characteristics of San Mateo County will set you up for long-term success.