Southern California Businesses for Sale: Buy & Invest Today
Looking for Southern California businesses for sale? DealStream’s comprehensive marketplace features hundreds of prime opportunities across Los Angeles, Orange County and San Diego—from established restaurants and retail shops to high-growth tech ventures. With detailed listings, insider insights and direct seller connections, finding and financing your next acquisition has never been easier. Browse now to discover the perfect Southern California business for sale and take the first step toward profitable ownership today.
Showcased Deals
Patented Nerve Monitoring Medical Device
The Company is in search of an opportunity to sell to an organization that has the ability to acquire and to continue to fully commercialize its unique and patented nerve saving device for prostate surgery. The Company’s device has received two FDA 510K Class II clearances and has four US Patents. The...
Relocatable San Diego Hospice
ACHC-accredited hospice agency licensed in California and approved to operate within San Diego County GSA*. The business is organized as a California C-Corporation and holds an active hospice license valid through October 11, 2027*. This opportunity offers a compliant platform for a qualified buyer...
World-Class Restoration & Sales Of Luxury Cars
**NOTE TO BUYERS: Buyers need to have at least $2.5 M available. There is no financing available. This is a lifestyle business. Established in 1989, the business is a premier restoration, sales, consignment, and service facility specializing in rare and investment-grade classic automobiles, with...
All Matching Deals
Relocatable San Diego Hospice
ACHC-accredited hospice agency licensed in California and approved to operate within San Diego County GSA*. The business is organized as a California C-Corporation and holds an active hospice license valid through October 11, 2027*. This opportunity offers a compliant platform for a qualified buyer...
San Diego Medicare Home Health for Sale
This opportunity represents the acquisition of a well-established Medicare-certified home health agency operating in San Diego County, California. The business is structured as a California Subchapter S-Corporation and has been in continuous operation since 2017, serving the local medical community...
Efficient Commercial Kitchen Operations Support
This service delivers repairs and maintenance for commercial kitchen equipment, helping varied clients remain compliant and operationally sound. Services cover gasket replacements, cutting-board fixes, and door hardware adjustments. The company operates remotely with the help of a custom tech platform...
Oceanside Hospice For Sale
This is a rare opportunity to acquire a clean, accredited hospice agency licensed in California and based in Southern California. The business operates under a California C-Corporation and is currently on a month-to-month lease at just $545/month, with approximately 800 sq. ft. of office space. The...
Home Health Business - Established, Turnkey
This is a distinguished and long-standing home health agency, is now available for acquisition. Established in December 2003, this California C-Corporation has earned recognition from the California Department of Public Health (CDPH) and National Government Services (NGS). Accredited by The Joint Commission...
Ventura County Home Health
This agency presents a rare opportunity for an experienced operator to acquire a compliant, active, and Joint Commission-accredited home health agency located in Ventura County, California. Established as a California C-Corporation, this agency has built a solid compliance track record with no liens,...
Home Health with +/-30 Census in El Monte
This is a rare opportunity to acquire a Joint Commission-accredited home health agency located in El Monte, CA. The agency is operating under a clean California S-Corporation with no CAPs, no billing issues, and fully up-to-date taxes. It has an active census of +/- 30 Medicare patients and is not subject...
Turnkey Hospice with Active Census – Act Fast
A prime opportunity to acquire an accredited and fully operational hospice agency in Los Angeles, California. This business is structured as a California Subchapter S-Corporation and holds re-accreditation as of October 31, 2023, with state licensing valid until December 9, 2025. With a current census...
ACHC-Accredited Hospice in San Gabriel
Hospice Business for Sale – San Gabriel, CA This ACHC-accredited hospice business, located in San Gabriel, California, offers a turnkey opportunity for buyers with healthcare experience. Established as a California C-Corporation, this agency is fully compliant, with recent accreditation through February...
Turnkey Hospice – No 36-Month Rule
IN CONTRACT An established, CDPH-accredited hospice agency, structured as a clean California C-Corporation, is now available for acquisition. Located in Los Angeles County, it serves an approved GSA covering Los Angeles, Orange, and Ventura Counties. Office: 1,100 sq. ft. | $2,500/month | Open lease...
Hospice Agency – Sherman Oaks, Los Angeles County
We are pleased to present a hospice agency opportunity located in the desirable Sherman Oaks region of Los Angeles County. This California Subchapter S-Corporation operates from a 650 sq. ft. office space under a three-year lease at $1,344 per month. The office is fully relocatable, providing operational...
Hospice with VA Contract & 15–20 Census
Offered at $1,200,000, this fully licensed and CHAP-accredited hospice agency serves Los Angeles and Orange County from its Riverside County office. The agency maintains a current patient census of 15–20, supported by an experienced team and key leadership who will remain post-closing to ensure operational...
Rare Orange County 3 Location Auto Body Repair
The Company is a well-established, multi-location auto body repair Business specializing in collision repair, painting, and body work. Operations span three fully equipped facilities in high-demand Orange County markets, enabling organized workflow, strong production capacity, and efficient throughput....
Non-Standard Insurance Agency w/Multiple Revenue
Founded by a minority entrepreneur, the agency was established in the 1990s with a mission to provide accessible insurance solutions and empower underserved clients. The agency addressed a significant market gap and tailored products for the Hispanic community. By focusing on educating clients via personalized...
Independent Music Equipment E-Com Store HQ
The Company is a well-established musical instrument retailer with a strong national reputation among manufacturers, dealers, and customers. It is a well-run, respected operation known for authenticity, specialized product knowledge, and exceptional customer service. Founded in the early 2000’s as a...
Non-Emergency Medical Transportation
Asking Type: Asset Sale Location: Southern California Reason for Sale: Passing of a family member UPDATE: final stage of contracts ready to be signed 2 logistic companies and one major healthcare provider (estimate potential income of $2million per year on multi year contract) A well-established...
$636K Rev – Wellness Media Brand
This company is a leading digital media brand focused on personal growth, wellness, and modern lifestyle content. It produces a top-ranked podcast supported by a highly engaged global audience. Over nearly a decade, it has expanded into multiple revenue streams including advertising, social partnerships,...
Established CPA firm with Large Team
This established Los Angeles area CPA firm has achieved 24% year-over-year growth and built a strong reputation for delivering high-level technical expertise, proactive client service, and steady profitability. Operating from two offices in affluent markets, the firm is powered by a highly skilled onshore...
Profitable Montessori-Future of Early Childhood Ed
This is the second of two schools for sale by the owners. Having envisioned improving Montessori education by addressing the significant lack of modern and authentic preschool options in the Greater Los Angeles area through acquisitions, the Sellers initially purchased four schools. This school...
45% Cashflow and Growing CPA firm in Orange County
--Strong Financials: $2.1M projected 2025 revenue; 3-year average growth of 18% per year; cash flow to owner 45-50%. --Real-Estate Niche: Deep relationships with developers, contractors, and investors; demand for ongoing tax strategy and financial-advisory support. --Elite Team & Culture: Credentialed,...
Virtual Book of Business with Premium Clients - CA
This well-curated book of business presents a rare opportunity for a buyer seeking exceptional profitability and a seamless transition. The client base has been carefully selected to align with the firm’s culture. It is comprised of appreciative, long-term clients who value individualized attention...
AI, VR and AR Training Solutions Company for Sale
The Company, with over 15 years of expertise in virtual reality (VR), augmented reality (AR), metaverse, and artificial intelligence (AI), is dedicated to transforming workforce performance across industries such as manufacturing, aviation, healthcare, defense, oil & gas, and pharmaceuticals. Their...
World-Class Restoration & Sales Of Luxury Cars
**NOTE TO BUYERS: Buyers need to have at least $2.5 M available. There is no financing available. This is a lifestyle business. Established in 1989, the business is a premier restoration, sales, consignment, and service facility specializing in rare and investment-grade classic automobiles, with...
Licensed Medicare Certified and JC Accredited HHA
Home Health Care Agency serving Seniors in Ventura and North-West Los Angeles Counties. The agency offers Home Health Care services including patients in their place of residence. With a mission to provide excellent care, enhance quality of life, ensure privacy and dignity, the agency delivers premium,...
Gene Therapy, Cell Therapy, Regulatory Consulting
Founded in 2011, the Company is a niche consulting and advisory firm serving in cell therapy, gene and gene-modified cell therapies, other regenerative medicines, tissue engineering, and cell-based drug discovery. The company’s core focus is to improve cell & gene therapy innovations by providing consulting...
Tips for Buying A Business In Southern California
Understand the Local Market Dynamics
Southern California is a diverse region with unique economic drivers, ranging from entertainment and technology to tourism and manufacturing. Before you buy a business, spend time researching the specific area and industry you’re considering. Look at local demographics, market trends, and economic indicators. Understanding competition, customer preferences, and regulatory requirements in cities like Los Angeles, San Diego, or Orange County can provide you with a decisive advantage and help you select an opportunity with solid long-term prospects.
Conduct Thorough Due Diligence
The success of your acquisition heavily depends on comprehensive due diligence. Go beyond financial statements: review leases, employee contracts, customer lists, vendor agreements, and any existing liabilities or legal issues. In Southern California, be especially mindful of regional concerns such as environmental regulations or zoning laws that could impact the business. Engage trusted professionals—accountants, attorneys, and business brokers—to uncover red flags, validate the business’s true value, and ensure all paperwork is in order before you commit.
Negotiate Terms to Fit Your Goals
When buying a business, the offer isn’t just about the price. Carefully negotiate terms such as seller financing, training periods, and transition support. In the competitive Southern California market, being flexible and creative with your deal structure—like staggered payments or earn-outs—can give you an edge over other buyers. Aim for terms that protect your interests while facilitating a smooth transition and maximizing your chances for success in your new venture.
Browse By Locations In California
- Los Angeles County, CA
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- Alameda County, CA
- Riverside County, CA
- Sacramento County, CA
- Contra Costa County, CA
- San Bernardino County, CA
- Los Angeles, CA
- San Francisco, CA
- San Diego, CA
- Sacramento, CA
- San Jose, CA
- Riverside, CA
- Long Beach, CA
- Irvine, CA
- Oakland, CA
- Fresno, CA
